Search results for "naphthalene"

showing 10 items of 267 documents

Synthesis of molecularly uniform model oligomers for 1,5-naphthalene diisocyanate and 1,4-butanediol based polyurethanes by using the 3,5-di-tert-but…

1997

A modified benzyloxycarbonyl (BOC) protective group, the 3,5-di-tert-butyl substituted BOC (3,5-tBBOC) group, was introduced to the stepwise synthesis of molecularly uniform oligourethanes based on 1,5-naphthalene diisocyanate (NDI) and 1,4-butanediol (BDO) for the protection of the amino functions of the starting material 1,5-naphthalene-diamine (NDA). The tert-butyl substituents of the 3,5-tBBOC group significantly improved the solubility of the intermediate products in the oligourethane synthesis. Thus, applying this modified protective group, reactions could be carried out, which were not possible with the conventional BOC group, due to the insolubility of the compounds in all suitable …

Telechelic polymerPolymers and PlasticsOrganic ChemistryChemical modification14-ButanediolCondensed Matter PhysicsOligomerchemistry.chemical_compoundEnd-groupchemistryPolymer chemistryMaterials ChemistryOrganic chemistryPhysical and Theoretical ChemistrySolubilityNaphthalenePolyurethane
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The anion impact on the self-assembly of naphthalene diimide diimidazolium salts

2017

Naphthalene diimide diimidazolium salts differing in the anion nature were synthesized and their properties as well as their self-assembly behaviour were investigated. In particular, we took into consideration the N,N′-bis-(1-octyl-3-propylimidazolium)-naphthalene diimide cations and anions differing in size, shape and coordination abilities like [I−], [BF4−] and [NTf2−]. After determination of thermal behaviour, using differential scanning calorimetry and thermal gravimetric analysis, the electrochemical stability and redox properties were assessed using cyclic voltammetry. The self-assembly behaviour of the salts was investigated using concentration and temperature-dependent spectroscopic…

Thermogravimetric analysiselectrochemical stabilityInorganic chemistry02 engineering and technology010402 general chemistryElectrochemistryNaphthalene diimide01 natural sciencesRedoxCatalysischemistry.chemical_compoundDifferential scanning calorimetryDiimideredox propertiesMaterials Chemistryhermal gravimetric analysisIsodesmic reactiondiimidazolium saltGeneral Chemistryself assemblySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyFluorescence0104 chemical scienceschemistryCyclic voltammetry0210 nano-technologyhermal gravimetric analysis;electrochemical stability;redox properties
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Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptos…

2001

In a search for retinoic acid (RA) receptor ligands endowed with potent apoptotic activity, a series of novel arotinoids were prepared. Because the stereochemistry of the C9-alkenyl portion of natural 9-cis-RA and the olefinic moiety of the previously synthesized isoxazole retinoid 4 seems to have particular importance for their apoptotic activity, novel retinoid analogues with a restricted or, vice versa, a larger flexibility in this region were designed and prepared. The new compounds were evaluated in vitro for their ability to activate natural retinoid receptors and for their differentiation-inducing activity. Cytotoxic and apoptotic activities were, in addition, evaluated. In general, …

Transcriptional ActivationProgrammed cell deathTetrahydronaphthalenesmedicine.drug_classReceptors Retinoic AcidRetinoic acidAntineoplastic AgentsApoptosisBenzoateschemistry.chemical_compoundInhibitory Concentration 50RetinoidsDrug DiscoverymedicineTumor Cells CulturedHumansRetinoidIsoxazoleCytotoxicityReceptorCell DifferentiationIsoxazolesIn vitroDrug Resistance MultipleBiochemistrychemistryApoptosisDrug Resistance NeoplasmMolecular MedicineDrug Screening Assays AntitumorCell DivisionJournal of medicinal chemistry
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ChemInform Abstract: Mono(cyclopentadienyl) Complexes of the Rare-Earth Metals

2010

I. Introduction 1953II. Overview of Synthesis, Structure, and Properties 1954A. Synthetic Methods 1954B. Ligands and Structures 1955III. Halo Complexes 1956A. General 1956B. Divalent Halo Complexes 1956C. Trivalent Halo Complexes 1957IV. Chalcogenido Complexes 1958A. General 1958B. Divalent Chalcogenido Complexes 1958C. Trivalent Chalcogenido Complexes 1959V. Pnicogenido Complexes 1960A. General 1960B. Divalent Amido and Phosphido Complexes 1960C. Trivalent Pnicogenido Complexes 19611. Bis(amido) Complexes 19612. Mixed Halo and Chalcogenido Complexes 1962VI. Hydrocarbyl and Silyl Complexes 1963A. General 1963B. Divalent Complexes 19631. Metallacarbaboranes 19632. Bimetallic Naphthalene Comp…

Trischemistry.chemical_classificationchemistry.chemical_compoundchemistrySilylationCyclopentadienyl complexArylPolymer chemistryGeneral MedicineBimetallic stripAlkylNaphthaleneDivalentChemInform
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Antileukemic ancistrobenomine B and related 5,1′-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius

2017

A striking feature of the metabolite pattern of the Southeast Asian liana Ancistrocladus tectorius (Ancistrocladaceae) is the predominance of 5,1′-coupled naphthylisoquinoline alkaloids. About 20 alkaloids of this coupling type have so far been discovered in this plant species. Here, we report on the isolation of four new 5,1′-linked naphthylisoquinolines from the twigs and stems of A. tectorius. Two of them, the ancistrobenomines B (5) and C (6), belong to the very rare group of alkaloids with a fully dehydrogenated isoquinoline portion. Likewise unusual for naphthylisoquinoline alkaloids is the presence of a hydroxymethylene group at C-3. Within the large class of meanwhile ca. 180 such n…

Trypanosoma brucei rhodesienseCircular dichroismStereochemistryMetabolitePlasmodium falciparumNaphthalenesSoutheast asian01 natural sciencesAntimalarialsMagnoliopsidachemistry.chemical_compoundAlkaloidsCell Line TumorDrug DiscoveryHumansIsoquinolinePharmacologyMolecular StructurePlant Stemsbiology010405 organic chemistryTrypanosoma brucei rhodesiensePlasmodium falciparumGeneral MedicineIsoquinolinesbiology.organism_classificationAntineoplastic Agents Phytogenic0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryAncistrocladaceaeTwo-dimensional nuclear magnetic resonance spectroscopyFitoterapia
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Wet-chemical approach for the cell-adhesive modification of polytetrafluoroethylene

2011

Polytetrafluoroethylene (PTFE), a frequently utilized polymer for the fabrication of synthetic vascular grafts, was surface-modified by means of a wet-chemical process. The inherently non-cell-adhesive polymer does not support cellular attachment, a prerequisite for the endothelialization of luminal surface grafts in small diameter applications. To impart the material with cell-adhesive properties a treatment with sodium-naphthalene provided a basis for the subsequent immobilization of the adhesion promoting RGD-peptide using a hydroxy- and amine-reactive crosslinker. Successful conjugation was shown with cell culture experiments which demonstrated excellent endothelial cell growth on the m…

Umbilical VeinsMaterials scienceSmall diameterPolymersSurface PropertiesCellCell Culture TechniquesBiomedical EngineeringBioengineeringNaphthalenesBiomaterialschemistry.chemical_compoundCell AdhesionmedicineHumansComposite materialPolytetrafluoroethylenechemistry.chemical_classificationPolytetrafluoroethyleneSodiumEndothelial CellsPolymerAdhesionCross-Linking Reagentsmedicine.anatomical_structureChemical engineeringchemistryCell cultureAdsorptionAdhesiveOligopeptidesEndothelial cell growthBiomedical Materials
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Theoretical calculations on the valence electronic structure of naphthalocyanine: comparison with experimental photoemission data

1993

Abstract We present a theoretical investigation of the electronic structure of metal-free 2,3-naphthalocyanine (2,3-H2Nc) using the valence effective Hamiltonian (VEH) technique. The VEH-DOVS curves obtained for 2,3-H2Nc are correlated with those calculated for naphthalene molecule and a one-to-one correspondence is found. From the electronic structure standpoint, naphthalocyanine has to be viewed as formed by joining four naphthalene moieties to the central carbon-nitrogen ring. An excellent quantitative agreement is found between VEH-DOVS curves and experimental photoemission data.

Valence (chemistry)Condensed matter physicsNaphthalocyanineChemistryMechanical EngineeringMetals and AlloysElectronic structureCondensed Matter PhysicsMolecular physicsElectronic Optical and Magnetic Materialssymbols.namesakechemistry.chemical_compoundMechanics of MaterialsMaterials ChemistrysymbolsDensity of statesMoleculeHamiltonian (quantum mechanics)Electronic band structureNaphthaleneSynthetic Metals
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Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia.

2016

Transmembrane anion transporters (anionophores) have potential for new modes of biological activity, including therapeutic applications. In particular they might replace the activity of defective anion channels in conditions such as cystic fibrosis. However, data on the biological effects of anionophores are scarce, and it remains uncertain whether such molecules are fundamentally toxic. Here, we report a biological study of an extensive series of powerful anion carriers. Fifteen anionophores were assayed in single cells by monitoring anion transport in real time through fluorescence emission from halide-sensitive yellow fluorescent protein. A bis-(p-nitrophenyl)ureidodecalin shows especial…

Yellow fluorescent proteinpotencyGeneral Chemical Engineeringsynthetic anion carriersCystic Fibrosis Transmembrane Conductance Regulator01 natural sciencesMadin Darby Canine Kidney CellsCell membranedeliverabilityta116Drug CarriersbiologyMolecular StructureChemistryBiological activitypersistenceCystic fibrosis transmembrane conductance regulatorTransmembrane proteinanionophoresmedicine.anatomical_structureBiochemistryPhosphatidylcholinesSteroidsChlorineAnionsCell SurvivalNaphthalenesta3111010402 general chemistryDogsBacterial ProteinsCyclohexanesmedicineAnimalsHumansIon transporterCell ProliferationIon Transport010405 organic chemistryCell MembranetoxicityTransporterEpithelial CellsHydrogen BondingGeneral ChemistryRats Inbred F3440104 chemical sciencesElectrophysiological PhenomenaLuminescent ProteinsMicroscopy FluorescenceCell cultureDrug Designbiology.proteinHeLa CellsNature chemistry
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Energy transfer between polyamine chains bearing naphthalene terminal units and k3[Co(CN)6]: An example of a molecular photoreactor

2002

Molecular photoreactors consisting of polyamine chains (receptors) bearing terminal naphthalene units (antennae) are described. The receptors are used to bind the substrate hexacyanocobaltate(III) and the antennae to transfer energy to the complex and thus promote a photoaquation reaction.

animal structuresBearing (mechanical)ChemistryEnergy transferSubstrate (chemistry)macromolecular substancesGeneral ChemistryPhotochemistrylaw.inventionchemistry.chemical_compoundTerminal (electronics)lawbiological sciencespolycyclic compoundssense organsPolyamineNaphthalene
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CCDC 825207: Experimental Crystal Structure Determination

2012

Related Article: J.Ferrando-Soria, D.Cangussu, M.Eslava, Y.Journaux, R.Lescouezec, M.Julve, F.Lloret, J.Pasan, C.Ruiz-Perez, E.Lhotel, C.Paulsen, E.Pardo|2011|Chem.-Eur.J.|17|12482|doi:10.1002/chem.201101459

catena-((mu3-(M)-22'-bis([carboxylato(oxidanidyl)methylidene]amino)-11'-binaphthalene)-tris(dimethyl sulfoxide)-copper(ii)-manganese(ii) dimethyl sulfoxide solvate trihydrate)Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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