Search results for "naro"

showing 10 items of 171 documents

Coronarografia diagnostica: evoluzione temporale in relazione ai progressi della PTCA

2002

Coronarografia diagnostica PTCA
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Coronarografia diagnostica e conseguenti scelte terapeutiche dopo l’avvento degli stent alla rapamicina: approccio attuale ed evoluzione degli ultimi…

2003

Coronarografia diagnostica stent rapamicina terapia
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Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia

2017

Abstract Ethnopharmacological relevance Ancient mediterranean diet was characterized by consuming the spontaneous forms of Cynara cardunculus L. (CCL), commonly called artichoke. Cultivated and/or spontaneous forms of CC studies have demonstrated that methanol extract of CCL flower and/or cynaropicrin showed remarkable anti-proliferative activity in vitro models of leukocyte cancer cell. Aim of the study Chronic myeloid leukemia (CML) is associated with a reciprocal translocation of the long arms of chromosomes 9 and 22 generating the BCR/ABL fusion gene, translated in the p210 BCR/ABL oncoprotein kinase. This chimeric protein is the target of a kinase inhibitor, imatinib, but the developme…

Cynara cardunculus L.Sesquiterpene0301 basic medicineSettore MED/06 - Oncologia MedicaFusion Proteins bcr-ablPharmacologyAntineoplastic AgentLactoneschemistry.chemical_compound0302 clinical medicinehemic and lymphatic diseasesDrug DiscoveryK562 cellABLChemistryChronic myeloid leukemiabreakpoint cluster regionMyeloid leukemiaLactoneCynaropicrinImatinib resistantChemotherapy Adjuvant030220 oncology & carcinogenesisImatinib MesylateChronic myeloid leukemia; Cynara cardunculus L.; Imatinib resistant; K562 cells; P210BCR/ABLoncoprotein; Antineoplastic Agents; Antineoplastic Agents Phytogenic; Cell Survival; Chemotherapy Adjuvant; Cynara; Drug Resistance Neoplasm; Fusion Proteins bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Lactones; Leukemia Myelogenous Chronic BCR-ABL Positive; Plant Extracts; Sesquiterpenes; Pharmacology; Drug Discovery3003 Pharmaceutical ScienceSesquiterpenesHumanmedicine.drugCell SurvivalAntineoplastic AgentsCynaraPlant Extract03 medical and health sciencesLeukemia Myelogenous Chronic BCR-ABL PositivemedicineHumansViability assayneoplasmsPharmacologyPlant ExtractsCell growthDrug Discovery3003 Pharmaceutical ScienceImatinibAntineoplastic Agents PhytogenicP210BCR/ABLoncoprotein030104 developmental biologyDrug Resistance NeoplasmCancer researchK562 CellsK562 cellsJournal of Ethnopharmacology
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Artichoke, Cynarin and Cyanidin Downregulate the Expression of Inducible Nitric Oxide Synthase in Human Coronary Smooth Muscle Cells

2014

Artichoke (Cynara scolymus L.) is one of the world’s oldest medicinal plants with multiple health benefits. We have previously shown that artichoke leaf extracts and artichoke flavonoids upregulate the gene expression of endothelial-type nitric oxide synthase (eNOS) in human endothelial cells. Whereas NO produced by the eNOS is a vasoprotective molecule, NO derived from the inducible iNOS plays a pro-inflammatory role in the vasculature. The present study was aimed to investigate the effects of artichoke on iNOS expression in human coronary artery smooth muscle cells (HCASMC). Incubation of HCASMC with a cytokine mixture led to an induction of iNOS mRNA expression. This iNOS induction was c…

Cynara scolymus L.nitric oxide; inducible NO synthase; vascular smooth muscle cells; artichoke; <i>Cynara scolymus</i> L.Myocytes Smooth MuscleCyanidinDown-RegulationNitric Oxide Synthase Type IIPharmaceutical ScienceCynarosidePharmacologyMuscle Smooth VascularArticleAnalytical ChemistryNitric oxideAnthocyaninslcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryEnosnitric oxideCynara scolymusDrug DiscoveryGene expressionHumansvascular smooth muscle cellsPhysical and Theoretical ChemistryPromoter Regions GeneticCells CulturedbiologyPlant Extractsinducible NO synthaseOrganic Chemistrybiology.organism_classificationCoronary VesselsVasoprotectivePlant LeavesNitric oxide synthaseGene Expression RegulationchemistryBiochemistryCinnamatesChemistry (miscellaneous)biology.proteinMolecular MedicineLuteolinartichokeMolecules
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STRATEGIE PENALI ED ANALISI ECONOMICA DELLA CRIMINALITÀ D'IMPRESA

DIRITTO PENALE CRIMINALITÀ D'IMPRESA CRIMINALITÀ ORGANIZZATA RICICLAGGIO DEL DENARO RESPONSABILITÀ DEGLI ENTI CONCORSO ESTERNO IN ASSOCIAZIONE A DELINQUERE ECONOMIC ANALYSIS OF LAW WHITE COLLAR CRIMESettore IUS/17 - Diritto Penale
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"Fuggire in boscaglia oscura". Osservazioni sul contrasto tra città e campagna nella Polonia rinascimentale

2018

Deep understanding of the notion concerning the opposition between cultural world represented by the city and nature connected with the life in the country was captured in Titians painting from 1511 depicting St. Anthonys miracle, taking place at the meeting of those two spaces. This sophisticated contrast, characteristic of the Italian Renaissance, was not reflected in Poland where the cities and their court culture were less representative. Mass contact of Polish students, visiting particularly Padua in the Renaissance, with the culture of Venetian villas, had a great impact mainly on ideological attempts to reflect humanistic models present in literaturę, art and lifestyle developing at …

Daniele BarbaroZamoyskiBernardo MorandoTizianoAlvise Cornaro
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Antropologia del denaro. Linguaggio, valore e ontologia sociale.

2014

Denaro Marx Searle langue Saussure moneta antropologiaSettore M-FIL/05 - Filosofia E Teoria Dei Linguaggi
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Stalinismi musiikissa : narodnost-käsite Neuvostoliiton musiikkipolitiikan diskursseissa 1930-luvulla

2016

Tässä maisterintutkielmassa tarkasteltiin yhden sosialistisen realismin alakäsitteen, narodnostin, merkitystä ja asemaa Neuvostoliiton musiikkipolitiikassa 1930-luvulla. Narodnost-käsitteen merkitystä selvitettiin suhteessa 1930-luvun Neuvostoliiton laajempiin poliittisiin diskursseihin, mikä toi esille Neuvostoliiton virallisen taidesuuntauksen muotoutumisen yhteyden tuon ajan historialliseen ja poliittiseen kontekstiin. Käsitteen määrittelyssä hyödynnettiin kahta historian ja kielen suhdetta tarkastelevaa teoreettista viitekehystä, diskurssintutkimusta ja käsitehistoriaa. Näiden teorioiden pohjalta luotiin lähestymistapa, jossa käsitteiden nähdään muodostuvan diskursseista. Näin ollen käs…

Diskurssintutkimus1930-lukusosialistinen realismikäsitehistoriamusiikkistalinismimusiikkipolitiikkanarodnost
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Travail posté et maladies cérébro- et cardiovasculaires : revue critique et synthèse des preuves épidémiologiques

2013

National audience; Une revue critique de la littérature a été menée sur le lien entre travail posté (TP) et survenue de maladies cérébro- et cardiovasculaires (MCCV). Dans plusieurs études de bonne qualité, le TP est associé à une augmentation modeste mais significative du risque de maladies cardiaques ischémiques fatales et non fatales. Les conclusions sont moins claires pour le lien avec la mortalité cardiovasculaire ischémique et les pathologies cérébrovasculaires. Sur le plan de la causalité, des biais de sélection difficiles à prendre en compte sur le plan méthodologique ne peuvent être écartés pour expliquer ces associations observées. Lien causal ou marqueur socio-économique ? Cette …

EPIDEMIOLOGIECHRONOBIOLOGIE[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologySYSTEME NERVEUX CENTRALFACTEUR DE RISQUETRAVAIL DE NUITHORAIRE DE TRAVAILINFARCTUSCOEURCORONAROPATHIE[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemTRAVAIL POSTECERVEAUROTATION DES POSTESHORAIRE ATYPIQUE[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyBIAIS[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemSYSTEME NERVEUX[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemDOSE-EFFETAPPAREIL CARDIOVASCULAIREMORTALITEACCIDENT VASCULAIRE CEREBRAL[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie[ SDV.NEU.NB ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieORGANISATION DU TRAVAIL
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Negocjacje w Unii Europejskiej na tle negocjacji międzynarodowych

2019

Celem niniejszego artykułu jest wskazanie zasadniczych cech negocjacji w UE na tle klasycznych negocjacji międzynarodowych. Pomimo założenia, że nie należy stawiać znaku równości między negocjacjami unijnymi a międzynarodowymi, to ich komparatystyka jest jak najbardziej uzasadniona, nie tylko z racji międzynarodowego charakteru integracji europejskiej, ale dlatego, że pozwala ona uchwycić wiele istotnych cech, właściwości i atrybutów negocjacji europejskich, które wynikają z natury UE, zwłaszcza w kontekście bezprecedensowej w historii stosunków międzynarodowych instytucjonalizacji procesów integracji. Artykuł składa się z dwóch części, dotyczących odpowiednio negocjacji międzynarodowych i …

EU Member States strategiesEU negotiationsnegocjacje unijnenegocjacje międzynarodowestrategie państw członkowskichinternational negotiations
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