Search results for "nations"
showing 10 items of 483 documents
Urban development and evolution of Valencian seaside destinations
2018
Mass tourism activity entails resource consumption and land uses usually difficult to be managed in a satisfactory way by urban planners. In practice, urbanism becomes a key tool in the des...
Gonadotrophin-releasing hormone analogue or dienogest plus estradiol valerate to prevent pain recurrence after laparoscopic surgery for endometriosis…
2015
Objectives To evaluate the efficacy of dienogest + estradiol valerate (E2V) and gonadotrophin-releasing hormone analogue (GnRH-a) in reducing recurrence of pain in patients with chronic pelvic pain due to laparoscopically diagnosed and treated endometriosis. Design Multi-center, prospective, randomized study. Setting Three university departments of obstetrics and gynecology in Italy. Population Seventy-eight women who underwent laparoscopic surgery for endometriosis combined with chronic pelvic pain. Methods Post-operative administration of dienogest + E2V for 9 months (group 1) or GnRH-a monthly for 6 months (group 2). Main outcome measures A visual analogue scale was used to test intensit…
Derecho de gentes antiguo y contemporáneo
2018
Confronto tra la tradizione del diritto delle genti e quello che si può considerare come la sua attualizzazione contemporanea, che viene individuata nella nozione di "jus cogens".
Presence phenomena in parkinsonian disorders: Phenomenology and neuropsychological correlates.
2020
Introduction The feeling of a presence that occurs in the absence of objectively identifiable stimuli is common in parkinsonian disorders. Although previously considered benign and insignificant, recent evidence suggests that presence phenomena may act as the gateway to more severe hallucinations and dementia. Despite this, we still know relatively little about these phenomena. Objective To examine parkinsonian disorder patients' subjective experience of presence phenomena, and retrospectively analyse their cognitive correlates, in order to elucidate the emergence of information processing deficits in parkinsonian disorders. Methods/design 25 patients who endorsed presence phenomena were as…
När barnet blir expert: Förklaringar av ord och procedurer i det digitala spelet Growtopia
2019
The ability to explain word meanings is central to a child’s language development and socialisation into different domains of language use. In previous research explanations have been shown to be linked to cognitive and linguistic development as well as academic language and discursive skills. This paper analyses what kinds of linguistic and discursive competences are put to use in explanation activities in interactions between an 8-year-old bilingual child (Albin) and his mother around a digital game. The data comes from a larger data set of video-recordings and field observation of children’s interactions around games. The analysis focuses on explanation sequences in which the child expli…
In Vitro Expression of the Endothelial Phenotype: Comparative Study of Primary Isolated Cells and Cell Lines, Including the Novel Cell Line HPMEC-ST1…
2002
Endothelial cell lines are commonly used in in vitro studies to avoid problems associated with the use of primary endothelial cells such as the presence of contaminating cells, the difficulty in obtaining larger numbers of cells, as well as the progressive loss of cell viability and expression of endothelial markers in the course of in vitro propagation. We have analyzed the characteristics defining distinctive endothelial phenotypes in the cell lines EA.hy926, ECV304, EVLC2, HAEND, HMEC-1, ISO-HAS-1 and a cell line recently generated in our laboratory, HPMEC-ST1.6R, and have compared these phenotypes with those found in primary human endothelial cells isolated from umbilical vein (HUVEC), …
[Hemostatic effectiveness of TachoSil® patches in radiofrequency assisted minor hepatic resection].
2011
Aim. Intra- and postoperative bleeding represents an extremely serious and frequent complication of hepatic surgery. The aim of this study was to evaluate the effectiveness of TachoSil (R) to improve hemostasis in radiofrequency assisted minor hepatic resection. Methods. Between July 2008 and June 2010, 31 patients underwent radiofrequency assisted minor hepatic resection. At the end of the liver resection a sponge of TachoSil (R) was applied on the liver. Results. The mean intraoperative bleeding from the liver was 56.1 mL (range 0-300 mL). No patients received intra- and postoperative blood transfusion. Surgical drains were removed between the first and the sixth-eight postoperative day. …
The mobility network of European tourists: a longitudinal study and a comparison with geo-located Twitter data
2018
Purpose This paper aims to provide a network study of the structural and dynamical characteristics of tourism flows in Europe from 1995 to 2012. Design/methodology/approach Travels in Europe were studied by following the network science research paradigm and by focusing on the whole network of intra-European tourism destinations. Network analysis was used to map and reveal the pattern of connections between states as shaped by bilateral tourism flows. Data were provided by the United Nations World Tourism Organization, and the data were integrated with tourism data available from national statistical offices of the individual countries, when necessary. Findings For 2012, results obtained f…
Inhalation solutions — Which ones may be mixed? Physico-chemical compatibility of drug solutions in nebulizers — Update 2013
2014
AbstractMany patients suffering from chronic respiratory diseases rely on inhalation therapy with nebulizers. About 25% of patients who need to inhale several different drugs per day save time by mixing them for simultaneous inhalation. This review presents a comprehensive overview of the available data concerning physico-chemical compatibility of commonly mixed nebulizer solutions and suspensions. Information is based on our in vitro studies and a thorough literature search.Results indicate that many nebulizer solutions/suspensions are mixable without provoking incompatibilities. However, certain excipients contained in some of the tested drug products could be identified as a reason for i…
New Potential Therapeutic Approach for the Treatment of B-Cell Malignancies Using Chlorambucil/Hydroxychloroquine-Loaded Anti-CD20 Nanoparticles
2013
Current B-cell disorder treatments take advantage of dose-intensive chemotherapy regimens and immunotherapy via use of monoclonal antibodies. Unfortunately, they may lead to insufficient tumor distribution of therapeutic agents, and often cause adverse effects on patients. In this contribution, we propose a novel therapeutic approach in which relatively high doses of Hydroxychloroquine and Chlorambucil were loaded into biodegradable nanoparticles coated with an anti-CD20 antibody. We demonstrate their ability to effectively target and internalize in tumor B-cells. Moreover, these nanoparticles were able to kill not only p53 mutated/deleted lymphoma cell lines expressing a low amount of CD20…