Search results for "naval"
showing 10 items of 153 documents
The effect of age on mitogen responsive T cell precursors in human beings is completely restored by interleukin-2.
1992
Abstract It is well known that the function of T lymphocytes is significantly impaired by advancing age. In the present study, attempts have been made to further characterize the T cell impairment of elderly subjects. Thus, we have performed limiting dilution microculture analysis to evaluate the precursor frequency of T lymphocytes responding to a mitogenic stimulus in old and young subjects. Furthermore we have evaluated the activity of recombinant interleukin-2 (rIL-2) on these cells. The results demonstrate that in older subjects the frequency of these precursors is significantly decreased. The in vitro treatment with rIL-2 increased the frequency of mitogen responsive T lymphocyte prec…
Applying Artificial Intelligence Methods to Detect and Classify Fish Calls from the Northern Gulf of Mexico
2021
Passive acoustic monitoring is a method that is commonly used to collect long-term data on soniferous animal presence and abundance. However, these large datasets require substantial effort for manual analysis
L'archivio del cantiere navale di Palermo
2015
Il cantiere navale di Palermo nasce all’interno di un disegno organico che ha come protagonista l’impero industria- le della più importante famiglia imprenditoriale del XIX secolo in Sicilia, i Florio. L’impresa nasce con lo scopo di garantire alla produzione isolana un ruolo nel disegno politico e nei piani economici del nuovo Regno d’Italia. In questa prima fase, il cantiere navale è caratterizzato da valenze fortemente identitarie legate al territorio urbano e alle espressioni culturali della borghesia di ne ‘800 a Palermo. Il passaggio dello stabilimento navale ad uno dei più potenti gruppi industriali italiani, facente capo ad una dinastia familiare del settentrione d’Italia, determina…
Separation of chitosomes and secretory vesicles from the ?slime? variant of Neurospora crassa
1987
Cells from the “slime” variant of Neurospora crassa were broken in isotonic conditions by use of triethanolamine buffer plus EDTA. After removal of large membranous structures by low-speed centrifugation, chitosomes and secretory vesicles were separated by means of gel filtration, precipitation of membranous contaminants with Concanavalin A, and centrifugation in sucrose or glycerol gradients. Polypeptidic composition of fractions enriched in secretory vesicles or chitosomes was found to be distinct. By these criteria we concluded that chitosomes and secretory vesicles represent different populations of microvesicles. Both microvesicular populations appeared free of endoplasmic reticulum an…
The structural effect between the output module and chromophore-binding domain is a two-way street via the hairpin extension.
2022
AbstractSignal transduction typically starts with either ligand binding or cofactor activation, eventually affecting biological activities in the cell. In red light-sensing phytochromes, isomerization of the bilin chromophore results in regulation of the activity of diverse output modules. During this process, several structural elements and chemical events influence signal propagation. In our study, we have studied the full-length bacteriophytochrome from Deinococcus radiodurans as well as a previously generated optogenetic tool where the native histidine kinase output module has been replaced with an adenylate cyclase. We show that the composition of the output module influences the stabi…
Influence of Wind on Suspended Matter in the Water of the Albufera of Valencia (Spain)
2021
Wind is one of the factors that has a great influence on suspended matter in lakes, especially in shallow lagoons. In order to know how wind affects the water in Albufera of Valencia, a shallow coastal lagoon, the measured variables of turbidity and transparency have been correlated with the estimates by processing Sentinel-2 satellite images with the Sen2Cor processor. Data from four years of study show that most of them are light to gentle easterly breezes and moderate to fresh westerly breezes. The results obtained show significant correlations between the measured variables and those obtained from the satellite images for total suspended matter and water transparency and with the averag…
The Impact of Grain Size Composition and Organic Matter Content on Magnetic Susceptibility of Anthropogenically Transformed Bottom Sediments, as Exem…
2018
The article presents the results of an analysis of the surface layer of bottom sediments in the naval harbour in Hel. During field work conducted in June 2013, 54 sediment samples were collected. The aim of the study was to examine magnetic susceptibility of harbour sediment as a parameter determining the degree of anthropopressure. As part of laboratory tests, grain size analysis was performed in order to determine organic matter content and magnetic susceptibility of the sediment. The study also measured the impact of environmental factors on fluctuations in the other studied parameters. The results demonstrate increased dynamics of sedimentary environment in the open part of the naval ha…
Back to the oligomeric state: pH-induced dissolution of concanavalin A amyloid-like fibrils into non-native oligomers
2016
The subtle interplay between long range electrostatic forces, hydrophobic interactions and short range protein-protein interactions regulates the onset/evolution of protein aggregation processes as well as the stability of protein supramolecular structures. Using a combination of FTIR spectroscopy, light scattering and advanced imaging, we present evidence on the main role of electrostatic forces in the formation and stability of amyloid-like fibrils formed from concanavalin A (ConA), a protein showing structural homology with the human serum amyloid protein. At high protein concentration, where protein-protein interactions cannot be neglected, we highlight a thermal-induced aggregation pat…
Improving the Downwind Sail Design Process by Means of a Novel FSI Approach
2021
The process of designing a sail can be a challenging task because of the difficulties in predicting the real aerodynamic performance. This is especially true in the case of downwind sails, where the evaluation of the real shapes and aerodynamic forces can be very complex because of turbulent and detached flows and the high-deformable behavior of structures. Of course, numerical methods are very useful and reliable tools to investigate sail performances, and their use, also as a result of the exponential growth of computational resources at a very low cost, is spreading more and more, even in not highly competitive fields. This paper presents a new methodology to support sail designers in ev…
Detecting Protein Aggregation on Cells Surface: Concanavalin A Oligomers Formation
2009
A number of neurodegenerative diseases involve protein aggregation and amyloid formation. Recently evidence has emerged indicating small-transient prefibrillar oligomers as the primary pathogenic agents. Noteworthy, strict analogies exist between the behaviour of cells in culture treated with misfolded non-pathogenic proteins and in pathologic conditions, this instance together with the observation that the oligomers and fibrils are characterised by common structural features suggest that common mechanisms for cytotoxicity could exists and have to be perused in common interactions involved in aggregation.We here report an experimental study on ConcanavalinA (ConA) aggregation and its effect…