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showing 10 items of 1983 documents
The effects of course length on freestyle swimming speed in elite female and male swimmers - a comparison of swimmers at national and international l…
2013
Abstract Freestyle swimming performance over 50 m, 100 m, 200 m, 400 m, 800 m and 1,500 m was compared on short (25 m) and long (50 m) course for 92,196 national swimmers (i.e. annual high score list Switzerland) and 1,104 international swimmers (i.e. finalists FINA World Championships) from 2000 to 2012. National and international swimmers of both sexes were on average 2.0 ± 0.6% faster on short than on long course. Sex-related differences in swimming speed were greater on short than on long course for international and national swimmers from 50 m to 800 m. Freestyle swimming performance improved across years for international swimmers in both short- and long-course whereas only male natio…
Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release
2022
Coxsackievirus A9 (CVA9), an enterovirus, is a common cause of pediatric aseptic meningitis and neonatal sepsis. During cell entry, enterovirus capsids undergo conformational changes leading to expansion, formation of large pores, externalization of VP1 N termini, and loss of the lipid factor from VP1. Factors such as receptor binding, heat, and acidic pH can trigger capsid expansion in some enteroviruses. Here, we show that fatty acid-free bovine serum albumin or neutral endosomal ionic conditions can independently prime CVA9 for expansion and genome release. Our results showed that CVA9 treatment with albumin or endosomal ions generated a heterogeneous population of virions, which could b…
Serological Follow-Up Study Indicates High Seasonal Coronavirus Infection and Reinfection Rates in Early Childhood
2022
Seasonal human coronaviruses (HCoVs) cause respiratory infections, especially in children. Currently, the knowledge on early childhood seasonal coronavirus infections and the duration of antibody levels following the first infections is limited. Here we analyzed serological follow-up samples to estimate the rate of primary infection and reinfection(s) caused by seasonal coronaviruses in early childhood. Serum specimens were collected from 140 children at ages of 13, 24, and 36 months (1, 2, and 3 years), and IgG antibody levels against recombinant HCoV nucleoproteins (N) were measured by enzyme immunoassay (EIA). Altogether, 84% (118/140) of the children were seropositive for at least one s…
Impact on Air Quality of the COVID-19 Lockdown in the Urban Area of Palermo (Italy).
2020
At the end of 2019, the first cases of coronavirus disease (COVID-19) were reported in Wuhan, China. Thereafter, the number of infected people increased rapidly, and the outbreak turned into a national crisis, with infected individuals all over the country. The COVID-19 global pandemic produced extreme changes in human behavior that affected air quality. Human mobility and production activities decreased significantly, and many regions recorded significant reductions in air pollution. The goal of our investigation was to evaluate the impact of the COVID-19 lockdown on the concentrations of the main air pollutants in the urban area of Palermo (Italy). In this study, the trends in the average…
COVID-19 Infection Process in Italy and Spain: Are the Data Talking?
2020
Background: COVID-19 has spread successfully worldwide in a matter of weeks. After the example of China, all the affected countries are taking hard-confinement measures to control the infection and to gain some time to diminish the big amount of cases that arrive to hospital. Although the measures in China reduced the percentages of new cases, this is not seen in other countries that have taken similar measures, such as Italy and Spain. Now we are in the middle of a battle trying to prevent the healthcare system from collapsing while it effectively responds to the needs of patients who are infected and require hospitalization. Methods: Using China as a mirror of what could happen in our cou…
Prevalence of SARS-CoV-2-IgG Antibodies in Children with CKD or Immunosuppression
2021
Coronavirus disease 2019 (COVID-19) rapidly spread from China as a pandemic, with Italy one of the most affected countries worldwide. Unlike adults, children have a milder presentation of COVID-19, even when affected by CKD or on immunosuppressive therapy for glomerulopathies and kidney
Exposing Empirical Links between COVID-19 Situation Report and Available Data: The Case of Nigeria
2020
Ever since the index case of COVID-19 was announced in Nigeria, the number of confirmed cases has gradually increased to 46,140 (about 4.5% of total confirmed cases in Africa) as the time of writing this article. This seemingly low number of confirmed cases has provoked heated debates among researchers. This cross-sectional study explores the Nigerian COVID-19 report to expose some links between the number of confirmed cases, testing, and some environmental conditions. The findings reveal that there is no state in Nigeria which has up to 12 confirmed cases per 10,000 population. That means, the number of confirmed COVID-19 cases is less than 0.15% of the population of people across each sta…
The Performative University: ‘Targets’, ‘Terror’ and ‘Taking Back Freedom’ in Academia
2020
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. This special issue assembles eight papers which provide insights into the working lives of early career to more senior academics, from several different countries. The first common theme which emerges is around the predominance of ‘targets’, enacting aspects of quantification and the ideal of perfect control and fabrication. The second theme is about the ensuing precarious evocation of ‘terror’ impacting on mental well-being, albeit enacted in diverse ways. Furthermore, several papers highlight a particular type of response, beyond complicity to…