Search results for "need"

showing 10 items of 854 documents

The prognostic value of sentinel lymph node micrometastases in patients with invasive breast carcinoma

2016

The prognostic value of sentinel lymph node micrometastases in invasive breast cancer patients is still widely debated. Even if, in the absence of unequivocal guidelines, the axillary lynphadenectomy is not still performed in the routine clinical care of these patients.We have retrospectively analyzed 746 patients with operable invasive breast cancer and clinically negative axillary lymph nodes. These patients underwent conservative surgery or total mastectomy with sentinel lymph node biopsy. Patients with micrometastases in the sentinel lymph node treated with axillary dissection has been checked and the involvement of the remaining lymph nodes analyzed. Patients with micrometastases in th…

AdultNeoplasms Hormone-DependentBiopsy Fine-NeedleBreast carcinomaBreast NeoplasmsHumansRadionuclide ImagingTechnetium Tc 99m Aggregated AlbuminMastectomyAgedRetrospective StudiesAged 80 and overSentinel Lymph Node BiopsyCarcinoma Ductal BreastMicrometaseMiddle AgedPrognosisCombined Modality TherapyCarcinoma LobularNeoplasm MicrometastasisLymphatic MetastasisBreast carcinoma; Micrometases; Sentinel lymph node; SurgeryAxillaLymph Node ExcisionFemaleSurgeryNeoplasm Recurrence LocalRadiopharmaceuticalsSentinel lymph node
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Kinin receptor status in normal and inflammed gastric mucosa

1997

No documented studies have been reported on the presence of B1 and B2 kinin receptors in the mammalian gastric mucosa. This first study aimed to immunolocalise sites of B1 and B2 kinin receptors in the human pyloric gastric mucosa and to evaluate its role in gastritis. Biopsies were obtained from patients with dyspepsia during endoscopic examination of the patient. The diagnosis and grading of the gastritis was performed on histological examination. Sections were immunostained for both B1 and B2 receptors using rabbit anti-human B1 and B2 kinin receptor antibodies. Control tissue was obtained from partial gastrectomy specimens, following surgical excision of the antrum for duodenal ulcers. …

AdultReceptor StatusPathologymedicine.medical_specialtyReceptor Bradykinin B2Molecular Sequence DataInflammationBiologyReceptor Bradykinin B1EpitheliumAntibody SpecificityGastroscopyPyloric AntrummedicineGastric mucosaAnimalsHumansAmino Acid SequenceDyspepsiaReceptorAntrumBradykinin Receptor AntagonistsPharmacologyReceptors BradykininBiopsy NeedleKininImmunohistochemistryPrecipitin TestsEpitheliummedicine.anatomical_structureGastric MucosaGastritisRabbitsmedicine.symptomGastritisFluorescein-5-isothiocyanateImmunopharmacology
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Information resources used by patients with inflammatory bowel disease: Satisfaction, expectations and information gaps.

2015

Abstract Background and purpose Information received by IBD patients about their disease is of particular importance. The objective of the study was to determine the information resources these patients used, together with their perceived information gaps and expected preferences. Patients and methods A prospective, observational, cross-sectional study conducted on IBD patients attending 13 Spanish hospitals during 2008. Patients completed a semi-structured 52-question survey. Results Survey was adequately completed by 379 of 385 patients (98%), of whom 57% had Crohn's disease and 43% ulcerative colitis. Mean patient age was 37.9 years (range, 16–76 years). Gastroenterologists were the most…

Adultmedicine.medical_specialtyAdolescentGeneral PracticeInformation Seeking BehaviorInformation needsDiseaseInflammatory bowel diseaseNurse's RoleYoung AdultPatient Education as TopicPatient ageSurveys and QuestionnairesmedicineHumansProspective StudiesPhysician's RoleAgedInternetHepatologybusiness.industryGastroenterologyMiddle Agedmedicine.diseaseInflammatory Bowel DiseasesUlcerative colitisSurgerySelf-Help GroupsCross-Sectional StudiesPatient SatisfactionFamily medicineObservational studybusinessGastroenterologia y hepatologia
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Risk of thromboembolism with thrombopoietin receptor agonists in adult patients with thrombocytopenia: systematic review and meta-analysis of randomi…

2012

Background and objective: Thrombopoietin receptor (TPOr) agonists (romiplostim and eltrombopag) are a new approach for the treatment of thrombocytopenia-associated conditions. They promote megakaryocyte differentiation, proliferation and platelet production. In the European Union, both are orphan drugs with an indication restricted to splenectomized immune thrombocytopenic purpura patients who are refractory to other treatments. Due to increasing platelet counts, these drugs may represent a risk for thromboembolic complications. We analyzed whether TPOr agonists affect thromboembolisms occurrence in adult thrombocytopenic patients. Materials and methods: We conducted a systematic review and…

Adultmedicine.medical_specialtyMegakaryocyte differentiationRecombinant Fusion ProteinsEltrombopagReceptors FcBenzoateslaw.inventionchemistry.chemical_compoundRandomized controlled triallawRisk FactorsInternal medicineHematologic AgentsThromboembolismmedicinemedia_common.cataloged_instanceHumansEuropean unionmedia_commonRandomized Controlled Trials as TopicRomiplostimbusiness.industryGeneral MedicineNumber needed to harmThrombocytopeniaSurgeryHydrazineschemistryThrombopoietinMeta-analysisRelative riskPyrazolesbusinessReceptors Thrombopoietinmedicine.drugMedicina clinica
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A Patient With Toxoplasmosis as a Cause of Submental Lymphadenopathy.

2019

Submental mass secondary to toxoplasmosis is a rare condition and physicians rarely consider its diagnosis. The presented case reports a 43-year-old woman referred with a constant, painless, edema located in the submental area for 2 weeks. Diagnosis of toxoplasmosis was established by the positive serological finding after an accurate medical history of the infectious disease specialist (the patient had eaten raw meat). The patient underwent antimicrobial therapy with resolution of lymphadenopathy. According to review of literature, the article aims to remind clinicians, maxillofacial surgeons, and otolaryngologists that a neck mass can be related to the infectious cause with involving of l…

Adultmedicine.medical_specialtyNeck massLymphadenopathyFacial lymphadenopathy oral disease toxoplasmosisToxoplasmosiInfectious disease specialist03 medical and health sciences0302 clinical medicineBiopsymedicineEdemaHumansMedical historyFacial lymphadenopathy030223 otorhinolaryngologyLymph nodemedicine.diagnostic_testbusiness.industryOral disease030206 dentistryGeneral Medicinemedicine.diseaseDermatologyToxoplasmosisSettore MED/32 - AudiologiaSubmental lymphadenopathySettore MED/31 - Otorinolaringoiatriamedicine.anatomical_structureOtorhinolaryngologyNeedle biopsySurgeryFemalemedicine.symptombusinessNeckToxoplasmosisHumanThe Journal of craniofacial surgery
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Clinical Care Conditions and Needs of Palliative Care Patients from Five Italian Regions: Preliminary Data of the DEMETRA Project

2020

In order to plan the right palliative care for patients and their families, it is essential to have detailed information about patients&rsquo

Adultmedicine.medical_specialtyPalliative careStreLeadership and Managementlcsh:MedicineNetworkHealth InformaticsSymptom assessmentassessment of healthcare needsArticlestress03 medical and health sciences0302 clinical medicineHealth Information ManagementmedicineInterRAI palliative care030212 general & internal medicineClinical careFrail olderbusiness.industryHealth Policylcsh:RCancerAssessment of healthcare needmedicine.diseaseComorbidityStress.Chronic disease030220 oncology & carcinogenesisFamily medicinePalliative careObservational studyEmotionalbusinessHealthcare
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Uterine leiomyoma metastasis as a first sign of breast cancer

1998

Uterine metastases from extragenital cancer are rarely reported in the literature. More frequently, the female genital tract is involved by direct extension from an adjacent pelvic organ. A 37-year-old woman had a myoma of the uterine wall and hypermenorrhea. The mass was laparoscopically enucleated, and frozen section examination was performed because it was macroscopically suspicious for sarcomatoid degeneration. The final diagnosis was metastatic carcinoma in the uterus of probable breast origin.

Adultmedicine.medical_specialtyPathologyUterusAntineoplastic AgentsBreast NeoplasmsMetastatic carcinomaMetastasisFatal OutcomeBreast cancermedicineHumansGynecologyFrozen section procedureUterine leiomyomaLeiomyomabusiness.industryBiopsy NeedleObstetrics and GynecologyCancerMyomamedicine.diseaseImmunohistochemistrymedicine.anatomical_structureChemotherapy AdjuvantLymphatic MetastasisUterine NeoplasmsFemaleLaparoscopyRadiotherapy AdjuvantbusinessThe Journal of the American Association of Gynecologic Laparoscopists
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Is avoidance of surgery possible in patients with perimenopausal ovarian tumors using transvaginal ultrasound and duplex color Doppler sonography?

1993

A total of 108 cases of small perimenopausal ovarian tumors (largest diameter, less than 7 cm) were evaluated by transvaginal sonography and duplex color Doppler sonography; 101 had criteria for benignity and 7 for malignancy. All cysts were punctured and aspirated to avoid unnecessary surgery (benign cases) and establish the cytologic diagnosis as well as to avoid the risk of leakage (malignant cases). Recurrence rate of benign punctured cysts was 25% within 1 year of follow up. No difference in recurrent rate was seen between pre- and postmenopausal patients (19 of 56 cases in the premenopausal group, and five of 28 cases in the postmenopausal group). The larger the cyst, the greater the …

Adultmedicine.medical_specialtyPuncturesSuctionMalignancyDiagnosis DifferentialRecurrencemedicineHumansRadiology Nuclear Medicine and imagingIn patientCystAgedUltrasonographyOvarian NeoplasmsRadiological and Ultrasound Technologybusiness.industryBenignityBiopsy NeedleUltrasoundColor dopplerMiddle Agedmedicine.diseaseSurgeryMenopauseOvarian CystsBloodDuplex (building)FemaleMenopausebusinessFollow-Up StudiesJournal of Ultrasound in Medicine
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Community-dwelling older adults and their informal carers call for more attention to psychosocial needs - Interview study on unmet care needs in thre…

2022

Background: Unmet care needs are usually defined in terms of receiving sufficient help in instrumental activities and activities of daily living. Research on unmet needs is mostly based on quantitative data. Older persons’ and informal carers’ views and experiences have received less attention. Methods: In this paper, we rely on a definition of unmet needs which includes both unmet needs due to insufficient care and those situations where informal carers experience undue strain. Using theory-driven content analysis, we examine community-dwelling older adults’ and their informal carers’ experiences of unmet needs: what kind of unmet needs they have, why and in which ways these needs are left…

Aged 80 and overAgingHealth (social science)tarpeetunmet needspsykososiaalinen tukipsychosocial needsinformal care3141 Health care scienceomaishoitajatCaregiversActivities of Daily LivingHumansIndependent LivingGeriatrics and GerontologyomaishoitohaastattelututkimusRespite CareGerontologyhealth care economics and organizationsikääntyneetQualitative ResearchAgedArchives of gerontology and geriatrics
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Taisnīga atlīdzība sabiedrības vajadzībām nepieciešamā nekustamā īpašuma atsavināšanas likuma kontekstā

2019

Sabiedrības vajadzībām nepieciešamā nekustamā īpašuma atsavināšanas likums paredz nekustamā īpašuma atsavināšanu sabiedrības vajadzībām labprātīgā vai piespiedu kārtā, saņemot taisnīgu atlīdzību. Pētījuma mērķis ir analizēt labprātīgas un piespiedu nekustamā īpašuma atsavināšanas sabiedrības vajadzībām procesa ietekmi uz taisnīgas atlīdzības noteikšanu nekustamā īpašuma īpašniekam. Iegūtie rezultāti liecina, ka slēdzot līgumu par labprātīgu nekustamā īpašuma atsavināšanu sabiedrības vajadzībām, nekustamā īpašuma īpašniekam ir lielākas iespējas iegūt taisnīgu atlīdzību Sabiedrības vajadzībām nepieciešamā nekustamā īpašuma atsavināšanas likuma kontekstā.

AlienationFair compensationPublic needsImmovable propertyJuridiskā zinātne
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