Search results for "neurolupus"

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Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus

2021

Background: The aim was to evaluate the diagnostic potential of serum neurofilament light chain (sNfL) measurements in patients with neuropsychiatric systemic lupus erythematosus (NPSLE). Methods: sNfL levels were determined by single molecule array assay in a retrospective cross-sectional cohort of 144 patients with systemic lupus erythematosus (SLE). After log-transformation of sNfL levels, mean sNfL levels were compared between NPSLE patients and SLE patients without neuropsychiatric disease using Student’s t test. Furthermore, the association of different neuropsychiatric manifestations with sNfL levels was assessed using a one-way analysis of variance (ANOVA) with post hoc analysis. As…

medicine.medical_specialtyNeurofilament lightCentral nervous systemGastroenterologychemistry.chemical_compoundInternal medicinePost-hoc analysismedicineRC346-429Original ResearchPharmacologyCreatininebusiness.industrymedicine.anatomical_structureneurofilament light chainNeurologychemistryCohortBiomarker (medicine)biomarkerMultiple linear regression analysisNeurology (clinical)Neurology. Diseases of the nervous systemCNSbusinessNeuropsychiatric diseaseneurolupusNPSLETherapeutic Advances in Neurological Disorders

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PEPhysical Sciences and Engineering
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LSLife Sciences
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