Search results for "neurophysiol"

Neurobiologie und System-Theorie eines visuellen Muster-Erkennungsmechanismus bei Kröten

1973

Quantitative behavioral experiments have shown that the toad uses mainly two types of gestalt information in prey/enemy discrimination: pattern extension in the direction of movement promotes, in general, the signal value prey, while extension perpendicular to the direction of movement promotes that of enemy. Registrations from single fibers and single cells at different stages on the visual path showed that the object extension perpendicular to the direction of movement is chiefly analysed by means of the retinal and thalamus pretectal nerve nets, whereas the extension in the direction of movement is analysed mostly by certain tectal nerve nets. Further neurobiological findings indicated t…

Machine learning for a combined electroencephalographic anesthesia index to detect awareness under anesthesia

2020

Spontaneous electroencephalogram (EEG) and auditory evoked potentials (AEP) have been suggested to monitor the level of consciousness during anesthesia. As both signals reflect different neuronal pathways, a combination of parameters from both signals may provide broader information about the brain status during anesthesia. Appropriate parameter selection and combination to a single index is crucial to take advantage of this potential. The field of machine learning offers algorithms for both parameter selection and combination. In this study, several established machine learning approaches including a method for the selection of suitable signal parameters and classification algorithms are a…

Altered processing of sensory stimuli in patients with migraine.

2014

Migraine is a cyclic disorder, in which functional and morphological brain changes fluctuate over time, culminating periodically in an attack. In the migrainous brain, temporal processing of external stimuli and sequential recruitment of neuronal networks are often dysfunctional. These changes reflect complex CNS dysfunction patterns. Assessment of multimodal evoked potentials and nociceptive reflex responses can reveal altered patterns of the brain's electrophysiological activity, thereby aiding our understanding of the pathophysiology of migraine. In this Review, we summarize the most important findings on temporal processing of evoked and reflex responses in migraine. Considering these d…

Satisfaction with and reliability of in-hospital video-EEG monitoring systems in epilepsy diagnosis – A German multicenter experience

2021

OBJECTIVE: To analyze satisfaction with and reliability of video-electroencephalography-monitoring systems (VEMS) in epilepsy diagnostics.; METHODS: A survey was conducted between December 2020 and January 2021 among German epilepsy centers using well-established customer satisfaction (CS) and quality assurance metrics.; RESULTS: Among 16 participating centers, CS with VEMS was low, with only 13% of customers actively recommending their system. Only 50% of users were satisfied with the overall performance of their VEMS, and a low 18% were satisfied with the manufacturer's customer service. User interface, software stability, lack of regular updates, and missing customer-oriented improvement…

Imaging synaptic zinc release in living nervous tissue

2001

Zinc enriched neurons have a pool of synaptic vesicles which contain free or loosely-bound zinc ions. The movement of the vesicular zinc ions into the synaptic clefts has been previously studied by microdialysis, fluorescence postmortem staining for zinc and radioactive zinc isotope. In this study the zinc fluorescence probe N-6-metoxy-p-toluensulfonamide quinoline (TSQ) has been applied as a tracer of synaptic release of zinc ions. This fluorochrome permeates cell membranes and when exposed to living brain slices gives rise to a staining pattern similar to that seen with autometallography. In the living brain slices, fluorescence emission persists after exposure to calcium saturated ethyle…

Neuropsychological Approaches to Visually-Induced Vection: an Overview and Evaluation of Neuroimaging and Neurophysiological Studies

2020

Abstract Moving visual stimuli can elicit the sensation of self-motion in stationary observers, a phenomenon commonly referred to as vection. Despite the long history of vection research, the neuro-cognitive processes underlying vection have only recently gained increasing attention. Various neuropsychological techniques such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) have been used to investigate the temporal and spatial characteristics of the neuro-cognitive processing during vection in healthy participants. These neuropsychological studies allow for the identification of different neuro-cognitive correlates of vection, which (a) will help to unravel …

Movement Perception in the Colliculus Superior

1977

Summary Neurophysiological measurements on cats' colliculus superior show results which are dependent on the movement of visual stimuli and movement of the background as well as on the movement of stimulus and background n!lative to each other. The movement dependent problems involved in pattern recognition by space time filters as regards resolution of details, distortion and eye movement are outlined in principle.

L'attention auditive: fonctions psychologiques et bases neurophysiologiques.

2006

The central control of oriented locomotion in insects - towards a neurobiological model

2010

A neurobiological model for the higher control of oriented locomotion in insects is developed here. It is based on studies in a genetic model insect, the fruit fly Drosophila melangaster. Reference is made to other insects, where respective functions are not yet studied in Drosophila. Flies can walk swiftly with up to 16 steps per second, each leg, on almost any substrate and in any orientation to the gravity vector. To bring about this astounding maneuverability and agility the central complex within the insect brain derives directional commands for the leg coordination centers in the thoracic nervous system. Neuroanatomical information is taken into account with regard to the general flow…

A model study for the progressive disruption of CA1 firing properties during Alzheimer’s disease

2011

Several independent studies show that β-Amyloid (Aβ) peptides accumulation, one of the characteristic hallmark of Alzheimer’s Disease (AD), can affect the normal neuronal activity in different ways causing an increase or a decrease in neuronal membrane excitability. For example, experimental evidence for a negative impact on neuronal membrane in animal models of AD has been obtained in dual patch recordings in rat hippocampal tissue slices, in which Aβ blocked K channels in pyramidal cell dendrites, causing an increase in dendritic membrane excitability. The resulting increased Ca2+ influx and excitoxicity may lead to dendritic degeneration. However, further experimental evidence suggests t…