Search results for "nomo"
showing 10 items of 500 documents
Development of a nomogram to estimate the quality of life in asthmatic children using the Childhood Asthma Control Test
2016
Background: Pediatric Asthma Quality of Life Questionnaire (PAQLQ) provides detailed information on QoL in asthmatic children, whereas Childhood Asthma Control Test (C-ACT) Questionnaire is the most validated instrument for asthma control. No study assessed the relationship between C-ACT and QoL in children by means of those instruments. The aim of this study was to determine whether a QoL estimation is possible using the C-ACT questionnaire in asthmatic children. Methods: Medical history, spirometry, C-ACT, and PAQLQ were assessed in 144 (60% male) outpatient asthmatic children from September 2011 to November 2014. A generalized linear model (GLM) for the prediction of PAQLQ was obtained t…
A model-based approach for assessing bronchodilator responsiveness in children: The conventional cutoff revisited
2020
An increase in FEV1 >=12% has been proposed in international guidelines as a clue to airway reversibility for diagnosing asthma in both adults and children. However, the validity of this cut-off has been questioned in the pediatric population. The aim of this study was to provide evidence that different cut-off values in BDR may be associated with better performance in discriminating among outpatient children with naïve asthma (A) and without asthma (NA). We compared three approaches: i) the conventional cutoff (12%); ii) the cut-off estimated by Youden's criteria; and iii) the cut-off based on a model-driven approach. we found that the conventional cut-off of 12% showed poor sensitivity in…
The value of Phosphohistone H3 as a cell proliferation marker in oral squamous cell carcinoma. A comparative study with Ki-67 and the mitotic activit…
2022
The Phosphohistone H3 (PHH3) antibody is recognized as a biomarker of cell proliferation, specific for cells in mitosis, of prognostic value in different malignant neoplasms, however it has been poorly studied in oral squamous cell carcinoma (OSCC). The main objective of this study was to evaluate the immunoexpression of the PHH3 in the OSCC, through the correlation with the immunoexpression of Ki-67, the mitotic activity index (MAI), histological grading, clinical-morphological parameters and the rate of survival. The study sample consisted of 62 cases of OSCC diagnosed in the Pathological Anatomy Laboratory of the Faculty of Dentistry, University of the Republic (Uruguay). In each of them…
Attractors for non-autonomous retarded lattice dynamical systems
2015
AbstractIn this paperwe study a non-autonomous lattice dynamical system with delay. Under rather general growth and dissipative conditions on the nonlinear term,we define a non-autonomous dynamical system and prove the existence of a pullback attractor for such system as well. Both multivalued and single-valued cases are considered.
The thymus at the crossroad of neuroimmune interactions.
2006
The numerous relationships existing between the nervous and the immune systems suggest that the neural networks present in the intrathymic microenvironment may influence T-cell development. We previously reported that thymic neural-crest-derived stromal cells are involved in a neural differentiation pathway and are able to produce neurotrophic factors and neurokines that are in turn able to increase and/or modulate thymic-stromal cell neuronal phenotype. We also showed that EGF promotes a neural phenotype in thymic epithelial cells by enhancing the expression of neuronal-specific markers, neurotransmitters, and neuropoietic cytokines, such as IL-6 and CNTF. More recently we showed that the …
Mini-drones swarms and their potential in conflict situations
2021
Drones are currently used for a wide range of operations, such as border surveillance, general surveillance, reconnaissance, transport, aerial photography, traffic control, earth observation, communications, broadcasting, and armed attacks. This paper examines the swarming and associated abilities to overwhelm a combatant as well as bring extra functionality by means of extra sensors spread throughout the swarm. The strategy of stealth is becoming increasingly less effective. Combatants can not only sense them, but can also successfully destroy them (although this cannot be said for nano-drones). For mini-drones, objectives can be enhanced by the strategy of overwhelming. peerReviewed
A Neural Multi-Agent Architecture for an Autonomous Mobile Robot Control
1999
The aim of this paper is to introduce a multi-agent architecture for an autonomous robot control oriented to obtain high design modularity and high parallelism of decision processes. A multi-agent approach allows us to design several specialized agents and each of them is optimized in order to solve a single part of the whole task. Each agent is able to cooperate with other agent exchanging information, so the robot is able to make the appropriate policy of management to reach a prefixed goal. We tested the proposed architecture with a simple application: an autonomous mobile robot performs object retrieval tasks into unknown structured environments. The robot is not given a priori map of t…
An original control strategy of storage systems for the frequency stability of autonomous grids with renewable power generation
2021
This work examines the operation of the autonomous power system of a geographical island assuming the integration of significant generation shares from renewable energy sources and the installation of the required storage systems. The frequency stability of the system is investigated considering different operating conditions, in terms of load demand and renewable power generation. The main focus of the work is an original control strategy specifically designed for power converters interfacing storage units to the grid. The proposed strategy is based on an extended frequency droop control, which selects specific droop settings depending on the operating mode—charge or discharge—of the stora…
Impact on Immune Tolerance induced by Medullary Thymic Epithelial Cells and Limbal Stem Cells
Un año y medio de estatuto del trabajo autonomo y su infradesarrollo : y en eso llegó una gran crisis económica
2008
El trabajo autónomo tiene una notable implantación en España y cumple una relativamente amplia funcionalidad en nuestro sistema económico y social. En el conjunto del tejido empresarial, es absolutamente hegemónica la figura del autónomo que no dispone de asalariados a su servicio, junto con el que emplea hasta dos trabajadores por cuenta ajena. Antes de la aprobación parlamentaria de la Ley 20/2007, su regulación resultaba muy fragmentaria, deficiente y obsoleta, sin atender a las profundas transformaciones que se han sucedido tras la llegada del posfordismo a este sector. Con la entrada en vigor de dicha norma, España dispone de una ley-marco, pionera en la Unión Europea y seguramente en …