Search results for "normal"
showing 10 items of 2571 documents
Fostering antioxidant defences: up-regulation of antioxidant genes or antioxidant supplementation?
2007
Vitamins have traditionally been considered as food components that are required in the normal diet to prevent deficiencies. However, a newer concept of the function of vitamins in nutrition has taken them beyond simply prevention of deficiency symptoms. This concept considers that many vitamins, when taken in relatively larges doses, have important functions beyond preventing deficiencies. Linus Pauling was instrumental in putting forward this concept, particularly for vitamin C. Thus, relatively high intakes of vitamins, and in particular vitamins C and E which are antioxidants, are considered to be healthy for the human population. This may be true in some special situations such as, for…
Experimental studies on continuous speech recognition using neural architectures with “adaptive” hidden activation functions
2010
The choice of hidden non-linearity in a feed-forward multi-layer perceptron (MLP) architecture is crucial to obtain good generalization capability and better performance. Nonetheless, little attention has been paid to this aspect in the ASR field. In this work, we present some initial, yet promising, studies toward improving ASR performance by adopting hidden activation functions that can be automatically learned from the data and change shape during training. This adaptive capability is achieved through the use of orthonormal Hermite polynomials. The “adaptive” MLP is used in two neural architectures that generate phone posterior estimates, namely, a standalone configuration and a hierarch…
Digitalisation of municipal healthcare collaboration with volunteers: a case study applying normalization process theory
2021
Abstract Background Increasing use of volunteers in healthcare requires structured collaboration between healthcare services and volunteers. The aim of this research was to explore critical issues and strategies in the implementation process of a digital solution for collaboration with and coordination of volunteers in municipal healthcare services. Methods Qualitative data collection was used to study implementation of a digital system for collaboration with volunteers in three Norwegian municipalities. Three rounds of interviews were conducted with healthcare employees from a volunteer centre and from municipality healthcare units in three municipalities: before implementation, and 6 and …
Chronic Adult Hydrocephalus
1974
Knowledge of Wallerian degeneration began in 1852 and, following experimental research on degeneration and regeneration of interrupted nerves, surgeons realized that reinnervation of end organs depended on growth of axons through the interrupted area of nerve. Therefore surgeons tried to reanastomose the stumps. Failures of reinnervation could not be blamed on lack of axoplasma metabolism and flow from cell body to suture line because the clinical observation of amputation neuromas and their constant recurrence demonstrated the unfailing delivery of axoplasma by the nerve cell body; at times to the deep concern of the surgeon, and the constant pain of the patient. The electron microscope sh…
On the influences of vegetation biomass on COSMO-Skymed X-band
2011
The knowledge of spatial and temporal variability of land cover is important to manage water resources for yield forecasting, water stress prediction, irrigation water management and flood protection. Cloud cover dramatically reduces the temporal resolution of optical data thus limiting their operational use; in addition, the spatial resolution is often inadequate for applications in heterogeneous areas. On the other hand, algorithms based on Synthetic Aperture Radar (SAR) implemented to retrieve vegetation parameters are not yet fully validated. New SAR missions (COSMO-Skymed and Terrasar-X) may represent a suitable source of data for operational uses due to the high spatial and temporal r…
OpenMolcas: From Source Code to Insight
2019
In this article we describe the OpenMolcas environment and invite the computational chemistry community to collaborate. The open-source project already includes a large number of new developments realized during the transition from the commercial MOLCAS product to the open-source platform. The paper initially describes the technical details of the new software development platform. This is followed by brief presentations of many new methods, implementations, and features of the OpenMolcas program suite. These developments include novel wave function methods such as stochastic complete active space self-consistent field, density matrix renormalization group (DMRG) methods, and hybrid multico…
Structure of longitudinal chromomagnetic fields in high energy collisions
2014
We compute expectation values of spatial Wilson loops in the forward light cone of high-energy collisions. We consider ensembles of gauge field configurations generated from a classical Gaussian effective action as well as solutions of high-energy renormalization group evolution with fixed and running coupling. The initial fields correspond to a color field condensate exhibiting domain-like structure over distance scales of order the saturation scale. At later times universal scaling emerges at large distances for all ensembles, with a nontrivial critical exponent. Finally, we compare the results for the Wilson loop to the two-point correlator of magnetic fields.
Informing, engaging, mobilizing or interacting: Searching for a European model of web campaigning
2011
This study presents data from content analyses of the websites of all parties that stood in the 2009 European parliamentary elections in France, Germany, Great Britain and Poland. It cross-nationally examines the main functions of the websites, the adoption of Web 1.0 and Web 2.0 features, and the political and cultural factors that determine parties’ online communication. The findings show that while the main website function varies across countries, Web 1.0 is still the dominant mode of campaigning. Moreover, offline inequalities within and between nations determine differences in parties’ individual online strategies: specifically, major parties in states with long histories of democrac…
Two ways to handle dependent uncertainties in multi-criteria decision problems☆
2009
Abstract We consider multi-criteria group decision-making problems, where the decision makers (DMs) want to identify their most preferred alternative(s) based on uncertain or inaccurate criteria measurements. In many real-life problems the uncertainties may be dependent. In this paper, we focus on multicriteria decision-making (MCDM) problems where the criteria and their uncertainties are computed using a stochastic simulation model. The model is based on decision variables and stochastic parameters with given distributions. The simulation model determines for the criteria a joint probability distribution, which quantifies the uncertainties and their dependencies. We present and compare two…
Clinical Utility of a Unique Genome-Wide DNA Methylation Signature for KMT2A-Related Syndrome
2022
Wiedemann–Steiner syndrome (WDSTS) is a Mendelian syndromic intellectual disability (ID) condition associated with hypertrichosis cubiti, short stature, and characteristic facies caused by pathogenic variants in the KMT2A gene. Clinical features can be inconclusive in mild and unusual WDSTS presentations with variable ID (mild to severe), facies (typical or not) and other associated malformations (bone, cerebral, renal, cardiac and ophthalmological anomalies). Interpretation and classification of rare KMT2A variants can be challenging. A genome-wide DNA methylation episignature for KMT2A-related syndrome could allow functional classification of variants and provide insights into the pathoph…