Search results for "note"
showing 10 items of 10709 documents
Towards oxalate-bridged iron(ii), cobalt(ii), nickel(ii) and zinc(ii) complexes through oxotris(oxalato)niobate(v): an open air non-oxidizing synthet…
2018
Four compounds with the formula [M2(dmphen)4(μ-C2O4)](ClO4)2·2dmso [M = Fe (1), Co (2) and Zn (4); dmphen = 2,9-dimethyl-1,10-phenanthroline] and [Ni2(dmphen)4(μ-C2O4)]3[NbO(C2O4)3]2·16H2O (3) have been synthesized using the tris(oxalato)oxoniobate(V) complex anion as the oxalate source, and their structures have been determined by single crystal X-ray diffraction. X-ray quality crystals of highly insoluble oxalate-bridged species were obtained by taking advantage of the slow release of oxalate by the tris(oxalato)oxoniobate(V) complex anion. The structures of 1–4 all contain oxalate-bridged dimetal(II) units with didentate dmphen molecules acting as end-cap ligands; electroneutrality is ac…
Maturation of a Key Resource – The Germanium-68/Gallium-68 Generator: Development and New Insights
2011
(68)Ge/(68)Ga radionuclide generators have been investigated for almost fifty years, since the cyclotron-independent availability of positron emitting (68)Ga via the (68)Ge/(68)Ga system had always attracted researches working in basic nuclear chemistry as well as radiopharmaceutical chemistry. However, it took decades and generations of research (and researchers) to finally reach a level of (68)Ge/(68)Ga radionuclide generator designs adequate to the modern requirements of radiometal labelling chemistry. Nevertheless, most of the existing commercial generator systems address aspects of (68)Ge breakthrough and safe synthesis of (68)Ga radiopharmaceuticals by adopting eluate post-processing …
Atrane complexes chemistry as a tool for obtaining trimodal UVM-7-like porous silica
2018
[EN] The use of atrane complexes as hydrolytic precursors enables the homogeneous incorporation of manganese (25Si/Mn48) throughout the porous walls of the nanoparticles of a surfactant-templated bimodal mesoporous silica (UVM-7). The subsequent leaching of the manganese nanodomains allows adding controlled microporosity to the host silica framework. The resulting final silica material presents three pore systems structured at different length scales: interparticle textural-type macroporosity (ca. 43.2nm), ordered intraparticle mesoporosity (ca. 2.63nm; after template removal), and well-dispersed microporosity (< 2nm; as consequence of the lixiviation of the Mn-rich domains). The good dispe…
Pyrene-Capped CdSe@ZnS Nanoparticles as Sensitive Flexible Oxygen Sensors in Non-Aqueous Media**
2014
A flexible, highly sensitive sensor of oxygen in non-aqueous solvents is described. It consists of CdSe/ZnS nanoparticles decorated with a considerable number of pyrene units, thus making the formation of the pyrene excimer possible. The emission of the pyrene excimer and that of the nanoparticle are suitably separated from each other and also from the excitation wavelength. This sensor can be applied as a ratiometric oxygen sensor by using the linear response of the pyrene excimer lifetime combined with the linear response of the nanoparticle excited state lifetime. This nanohybrid has been assayed in seven media with different dielectric constants and viscosities over the whole oxygen con…
Orientation-Dependent Handedness of Chiral Plasmons on Nanosphere Dimers: How to Turn a Right Hand into a Left Hand
2016
Optical activity, which is used as a discriminator of chiral enantiomers, is demonstrated to be orientation dependent on individual, and nominally achiral, plasmonic nanosphere dimers. Through measurements of their giant Raman optical activity, we demonstrate that L/R-handed enantiomers can be continuously turned into their R/L-handed mirror images without passing through an achiral state. The primitive uniaxial multipolar response, with demonstrable broken parity and time reversal symmetry, reproduces the observations as resonant Raman scattering on plasmons that carry angular momentum. The analysis underscores that chirality does not have a quantitative continuous measure and recognizes t…
The Chorioallantoic Membrane Assay in Nanotoxicological Research—An Alternative for In Vivo Experimentation
2020
Nanomaterials unveil many applicational possibilities for technical and medical purposes, which range from imaging techniques to the use as drug carriers. Prior to any human application, analysis of undesired effects and characterization of their toxicological profile is mandatory. To address this topic, animal models, and rodent models in particular, are most frequently used. However, as the reproducibility and transferability to the human organism of animal experimental data is increasingly questioned and the awareness of animal welfare in society increases at the same time, methodological alternatives are urgently required. The chorioallantoic membrane (CAM) assay is an increasingly popu…
La investigación crítica de las representaciones sociales de la ciencia: nanotecnologías, democratización del conocimiento científico y par
2013
El planteamiento del capítulo señala la importancia y centralidad de la investigación social de la cara oculta de la ciencia, de sus aplicaciones técnicas y de los procesos de participación ciudadana en la decisión sobre sus usos sociales. También que dicha reflexión es clave para entender el papel que los usos sociales de la ciencia pueden estar jugando para incrementar, no ya en el bienestar individual y colectivo, sino en las desigualdades sociales, económicas y ecológicas que comporta la actual globalización neoliberal. En términos de participación ciudadana, la tesis de fondo sostiene que en el actual sistema capitalista no se puede habla de sociedades democráticas, con rigor científic…
Kompensācija cietušajam par nodarīto kaitējumu kriminālprocesā
2015
Mūsdienās aizvien ir aktuāla morālā kaitējuma kompensācijas noteikšana kriminālprocesā, it sevišķi tāpēc, ka morālam kaitējumam nepastāv precīzi nosakāms naudas ekvivalents. Darba mērķis ir izveidot universālu, ilgspējīgu morālā kaitējuma noteikšanas koncepciju, skaidri noteikt kritērijus, kuri tiesnešiem jāņem vērā, lemjot par kaitējuma kompensācijas apmēru, turklāt izpētīt arī praktiskos jautājumus, kas saistās ar kompensācijas pieteikšanu. Pētījuma rezultātā izstrādāta ilgspējīga morālā kaitējuma koncepcija, kurā noteikti rekomendējoši, taču aptuveni kompensācijas piešķiršanas apmēri, kā arī piedāvāti vairāki Kriminālprocesa likuma grozījumi.
Maksātnespējas procesa administratora rīcības rezultātā radīto zaudējumu atlīdzināšanas pienākums.
2020
Lai kreditoriem radītais zaudējumu apmērs juridiskas vai fiziskas personas maksātnespējas pasludināšanas brīdī neturpinātu palielināties arī pēc maksātnespējas pasludināšanas, par parādnieka pārstāvēttiesīgo personu tiek iecelts maksātnespējas procesa administrators. Lai gan maksātnespējas procesa administrators ir juridiskās nozares profesionālis, praksē rodas situācijas, kad maksātnespējas procesa administratora rīcības rezultātā tiek nodarīts kaitējums kreditoriem vai trešajām personām. Tomēr tiesību aktos nav expresis verbis noteikts, ka maksātnespējas procesa administratora civiltiesiskā atbildība būtu pielīdzināma komercsabiedrības valdes locekļa civiltiesiskai atbildībai. Autore darb…
Prevention of Dominant IgG Adsorption on Nanocarriers in IgG‐Enriched Blood Plasma by Clusterin Precoating
2019
Abstract Nanocarriers for medical applications must work reliably within organisms, independent of the individual differences in the blood proteome. Variation in the blood proteome, such as immunoglobulin levels, is a result of environmental, nutrition, and constitution conditions. This variation, however, should not influence the behavior of nanocarriers in biological media. The composition of the protein corona is investigated to understand the influence varying immunoglobulin levels in the blood plasma have on the interactions with nanocarriers. Specifically, the composition of the nanocarriers' coronas is analyzed after incubation in plasma with normal or elevated immunoglobulin G (IgG)…