Search results for "nov"
showing 10 items of 6155 documents
Neuromuscular performance in voluntary bilateral and unilateral contraction and during electrical stimulation in men at different ages.
1995
A group of 33 men divided into three different age groups, M30 years (n = 11), M50 years (n = 12) and M70 years (n = 10) volunteered as subjects for examination of their maximal voluntary isometric bilateral and unilateral forces and force-time curves of the knee extensor muscle group as well as electromyogram activity of the vastus lateralis, vastus medialis and rectus femoris muscles of the right and/or left leg contractions. Electrical stimulation (ES) of 50 Hz was also given by two surface tin electrodes for each subject and each leg separately with the maximal tolerable intensity for recording the isometric force evoked. The maximal force produced by the voluntary isometric unilateral …
The development of involuntary and voluntary attention from childhood to adulthood: A combined behavioral and event-related potential study
2006
Abstract Objective This study investigated auditory involuntary and voluntary attention in children aged 6–8, 10–12 and young adults. The strength of distracting stimuli (20% and 5% pitch changes) and the amount of allocation of attention were varied. Methods In an auditory distraction paradigm event-related potentials (ERPs) and behavioral data were measured from subjects either performing a sound duration discrimination task or watching a silent video. Results Pitch changed sounds caused prolonged reaction times and decreased hit rates in all age groups. Larger distractors (20%) caused stronger distraction in children, but not in adults. The amplitudes of mismatch negativity (MMN), P3a, a…
T cells involved in psoriasis vulgaris belong to the Th1 subset
1994
Although the pathogenesis of psoriasis vulgaris is still unknown, several characteristics point to an immunologically mediated process. Epidermal psoriatic lesions are characterized by a hyperproliferation of keratinocytes and an infiltration of T lymphocytes and granulocytes. Because the former may be mediated in part by lymphokines secreted by T cells, we have focused our interest on the in vivo and in vitro cytokine secretion patterns of T lymphocytes from psoriatic lesions. In five patients T lymphocytes were obtained from epidermal specimens. The cells were propagated with lectin and irradiated feeder cells and subsequently cloned by limiting dilution. The resulting T-cell clones were …
Poorly differentiated synovial sarcoma: A case report
2001
Poorly differentiated synovial sarcoma is a rare soft tissue tumor. We studied a case arising in the pleural cavity of a young subject, characterised by the presence of spindle cell, small cell, and large epithelioid cell areas. We performed stains for mucosubstances and analysed the expression of cytokeratins 5/6, 7, 8, 18, 19, CEA, CD34, Ber-Ep4 and calretinin to characterize the phenotype of this neoplasm. We furthermore assessed immunohistochemically the presence of p53, Bcl-2, Bax and caspase 3, four apoptotic markers, to evaluate a relationship between apoptotic activity and the behaviour of this tumor. Our findings showed a strong presence of calretinin, p53 and Bcl-2 in all three ar…
klebsiella pneumoniae-reactive t cells in blood and synovial fluid of patients with ankylosing spondylitis comparison with hla–b27 + healthy control …
1995
Objective To study the frequency of Klebsiella pneumoniae-responsive T cells in the peripheral blood (PB) of ankylosing spondylitis (AS) patients compared with that in healthy HLA-B27+ donors, and to examine T lymphocyte clones (TLC) derived from AS patient synovial fluid (SF) for the presence of Klebsiella reactivity. Methods Limiting dilution analysis of PB T cells in 8 patients with active AS and in 8 HLA-B27+ healthy subjects was used to determine the frequency of PB T cells responsive to K pneumoniae and Escherichia coli GroEL. SF T cells from a patient with active AS were cloned, and 125 TLC were characterized in proliferation assays. Results There were fewer T cells in the PB of AS p…
The relationship of personality traits to substance abuse in patients with bipolar disorder
2007
AbstractPurposeThe aim of this study is to determine if personality traits contribute to the likelihood of substance abuse in Bipolar Disorder (BD).Subjects/materials and methodsFifty-nine patients meeting DSM-IV criteria for BD: 20 without any history of Substance Related Disorder (SRD), 21 with a lifetime history of SRD but without current SRD, and 18 with current SRD. Patients filled out the TCI, the differences were analyzed by ANOVA and the likelihood was obtained by Multinomial Logistic Regression.ResultsOnly Novelty Seeking (NS) is statistically different between the groups. Patients with BD with current SRD have higher rates in NS than those with past SRD, and those without a histor…
Infant information processing and family history of specific language impairment: converging evidence for RAP deficits from two paradigms
2007
An infant's ability to process auditory signals presented in rapid succession (i.e. rapid auditory processing abilities [RAP]) has been shown to predict differences in language outcomes in toddlers and preschool children. Early deficits in RAP abilities may serve as a behavioral marker for language-based learning disabilities. The purpose of this study is to determine if performance on infant information processing measures designed to tap RAP and global processing skills differ as a function of family history of specific language impairment (SLI) and/or the particular demand characteristics of the paradigm used. Seventeen 6- to 9-month-old infants from families with a history of specific l…
Neural net classification of REM sleep based on spectral measures as compared to nonlinear measures
2001
In various studies the implementation of nonlinear and nonconventional measures has significantly improved EEG (electroencephalogram) analyses as compared to using conventional parameters alone. A neural network algorithm well approved in our laboratory for the automatic recognition of rapid eye movement (REM) sleep was investigated in this regard. Originally based on a broad range of spectral power inputs, we additionally supplied the nonlinear measures of the largest Lyapunov exponent and correlation dimension as well as the nonconventional stochastic measures of spectral entropy and entropy of amplitudes. No improvement in the detection of REM sleep could be achieved by the inclusion of …
Nonlinear analysis of continuous ECG during sleep II. Dynamical measures
2000
The hypothesis that cardiac rhythms are associated with chaotic dynamics implicating a healthy flexibility has motivated the investigation of continuous ECG with methods of nonlinear system theory. Sleep is known to be associated with modulations of the sympathetic and parasympathetic control of cardiac dynamics. Thus, the differentiation of ECG signals recorded during different sleep stages can serve to determine the usefulness of nonlinear measures in discriminating ECG states in general. For this purpose the following six nonlinear measures were implemented: correlation dimension D2, Lyapunov exponent L1. Kolmogorov entropy K2, as well as three measures derived from the analysis of unsta…
Surrogate data analysis of sleep electroencephalograms reveals evidence for nonlinearity
1996
We tested the hypothesis of whether sleep electroencephalographic (EEG) signals of different time windows (164 s, 82 s, 41 s and 20.5 s) are in accordance with linear stochastic models. For this purpose we analyzed the all-night sleep electroencephalogram of a healthy subject and corresponding Gaussian-rescaled phase randomized surrogates with a battery of five non-linear measures. The following nonlinear measures were implemented: largest Lyapunov exponent L1, correlation dimension D2, and the Green-Savit measures delta 2, delta 4 and delta 6. The hypothesis of linear stochastic data was rejected with high statistical significance. L1 and D2 yielded the most pronounced effects, while the G…