Search results for "novel"

showing 10 items of 684 documents

Two novel amino acid substitutions in highly conserved regions of prion protein (PrP) and a high frequency of a scrapie protective variant in native …

2019

Background Polymorphisms of the prion protein gene may influence scrapie susceptibility in small ruminants through modified protein conformation. At least 47 amino acid substitutions and 19 silent polymorphisms have been described in goat PRNP reported from several countries. The objective of this study was to investigate PRNP polymorphisms of native Ethiopian goat breeds and compare the results with other goat breeds. Results The analysis of the prion protein gene PRNP in 229 goats belonging to three of the main Ethiopian native goat breeds showed a remarkably high frequency (> 34.6%) of p.(Asn146Ser) in these breeds, a variant involved in scrapie resistance in Cyprus. In addition, two nov…

Genotype040301 veterinary sciencesanimal diseasesScrapieBiologyPrion ProteinPrion ProteinsPRNP0403 veterinary science03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoProtein structureEthiopian native goats; novel polymorphismsGoat DiseaseAnimalsGenetic Predisposition to DiseasePrion proteinGene030304 developmental biologyGeneticschemistry.chemical_classification0303 health sciencesGenetic diversityPrPlcsh:Veterinary medicineGoat DiseasesPolymorphism GeneticGeneral VeterinaryAnimalGoatsEthiopian native goatnovel polymorphism04 agricultural and veterinary sciencesGeneral Medicinenervous system diseasesAmino acidchemistryAmino Acid SubstitutionGoatlcsh:SF600-1100PRNPEthiopiaPrion ProteinsResearch ArticleScrapie
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Recensione a: F. DI LEGAMI, Le novelle di Gentile Sermini, Padova 2009 (in «Studi Medievali», n.s., 53,2, 2012)

2012

Si tratta di una recensione al vol. di Flora Di Legami, Le novelle di Gentile Sermini, pubblicato a Padova nel 2009, che presenta la prima analisi completa e approfondita della raccolta novellistica di Gentile Sermini, scrittore senese della prima metà del sec. XV.

Gentile Sermininovellistica italianaSettore L-FIL-LET/10 - Letteratura Italiana
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La tentazione del moderno. Gesualdo Bufalino e il romanzo europeo del primo Novecento

2020

The work of Gesualdo Bufalino relies on a permanent dialogue with the great modernist models of European fiction. A whole network of allusions, innuendos and micro-quotations from the great novels of Mann, Kafka, Proust, Musil, Joyce, Woolf, is scattered among the pages of Diceria dell’untore, a novel which was conceived as a “serious game” using previous textual materials and recombining them in order to create a new architecture of meaning. In Bufalino’s following books as well, the central position assigned to the Ego coexists with a plot in which the inner experiences of the characters count more than the objective facts. There is an urgency of truth and meaning. The fact that this trut…

Gesualdo Bufalino modernist novel Mann Kafka Proust quote intertextualitySettore L-FIL-LET/11 - Letteratura Italiana Contemporanea
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"Non giucando ... ma novellando": Primi appunti per una lettura comunitaria del Decameron

2015

Giovanni Boccaccio

Giovanni Boccaccio Decameron gioco novellaSettore L-FIL-LET/14 - Critica Letteraria E Letterature ComparateSettore L-FIL-LET/10 - Letteratura Italiana
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A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia

2000

Winterpacht, Andreas, Katja Hilbert, Christiane Stelzer, Thorsten Schweikardt, Heinz Decker, Hugo Segerer, Jürgen Spranger, and Bernhard Zabel. A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia. Physiol. Genomics 2: 9–12, 2000.—Fibroblast growth factor receptor 3 (FGFR3) is a glycoprotein that belongs to the family of tyrosine kinase receptors. Specific mutations in the FGFR3 gene are associated with autosomal dominant human skeletal disorders such as hypochondroplasia, achondroplasia, and thanatophoric dysplasia. Hypochondroplasia (HCH), the mildest form of this group of short-limbed dwarfism disorders, results in ∼60% of cases from a mut…

GlycosylationGlycosylationPhysiologyDNA Mutational AnalysisHypochondroplasiaOsteochondrodysplasiasReceptor tyrosine kinaseMicechemistry.chemical_compoundGeneticsmedicineAnimalsHumansPoint MutationReceptor Fibroblast Growth Factor Type 3N-Glycosylation SiteGeneticschemistry.chemical_classificationBinding SitesBase SequencebiologyInfantDNAProtein-Tyrosine Kinasesmedicine.diseaseReceptors Fibroblast Growth FactorMolecular biologyProtein Structure TertiaryMice Inbred C57BLAmino Acid SubstitutionchemistryFibroblast growth factor receptorMutationbiology.proteinFemaleGlycoproteinNovel mutationPhysiological Genomics
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La novela gráfica como recurso didáctico en tiempos de pandemia: una propuesta intercultural para dinamizar la asignatura de Conversación del Grado e…

2022

El azote pandémico ha marcado un implacable punto de inflexión en la escena educativa. Concretamente, en la R. P. China, contexto en el que se inserta la presente experiencia, la docencia en línea ha pasado a ser la tónica de una parte significativa del profesorado hispanohablante sin opción de regreso. Dicha coyuntura, además de dificultar la enseñanza de una asignatura eminentemente comunicativa como Conversación, plantea la imperiosa necesidad de redefinir el proceso didáctico al abrazo de propuestas que, por un lado, comulguen con la identidad del alumnado meta y, por otro, estimulen su participación activa en el aula virtual. El presente artículo contextualiza y desgrana la propuesta d…

Graphic novelPeople’s Republic of ChinaRepública Popular ChinaIntercultural communicative competenceCompetencia comunicativa interculturalCOVID-19UNESCO:PEDAGOGÍANovela gráficaForo de profesores de E/LE
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Prevalence and 30-Day Mortality in Hospitalized Patients With Covid-19 and Prior Lung Diseases.

2021

Patients with pre-existing respiratory diseases in the setting of COVID-19 may have a greater risk of severe complications and even death.A retrospective, multicenter, cohort study with 5847 COVID-19 patients admitted to hospitals. Patients were separated in two groups, with/without previous lung disease. Evaluation of factors associated with survival and secondary composite end-point such as ICU admission and respiratory support, were explored.1,271 patients (22%) had a previous lung disease, mostly COPD. All-cause mortality occurred in 376 patients with lung disease (29.5%) and in 819 patients without (17.9%) (Previous lung disease is a risk factor for mortality in patients with COVID-19.…

HOPE-COVID-19 Health Outcome Predictive Evaluation for COVID-19Respiratory diseasesOriginal30-Day mortalityenfermedades respiratoriasACE2 angiotensin converting enzyme IIlaw.invention0302 clinical medicineCQ/HCQ chloroquine/hydroxychloroquinelawCOPDrespiratory diseasesPrognosisICU intensive care unitIntensive care unitSTROBE strengthening the reporting of observational studies in epidemiologypronósticomedicine.anatomical_structureEPOCCohort studyPulmonary and Respiratory Medicinemedicine.medical_specialty30-day mortalityRT-PCR real time reverse transcriptase-polymerase chain reactionSARS-CoV-2 severe acute respiratory syndrome coronavirus 2WHO World Health OrganizationMERS middle east respiratory syndrome03 medical and health sciencesInternal medicinemedicineCOPDCOVID-19 2019 novel coronavirusRisk factorIQR interquartile rangeLungmortalidad a 30 díasbusiness.industryFEV1 forced expiratory volume in one secondCOVID-19Retrospective cohort studymedicine.diseaseHR hazard ratioICS inhaled corticosteroidsCI confidence intervalCoronavirusCOPD chronic obstructive pulmonary disease030228 respiratory systemRespiratory failureILD interstitial lung diseaseMiddle East respiratory syndromeprognosisHFNC high flow nasal cannulabusiness
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Novel Food Processing and Extraction Technologies of High-Added Value Compounds from Plant Materials

2018

Some functional foods contain biologically active compounds (BAC) that can be derived from various biological sources (fruits, vegetables, medicinal plants, wastes, and by-products). Global food markets demand foods from plant materials that are “safe”, “fresh”, “natural”, and with “nutritional value” while processed in sustainable ways. Functional foods commonly incorporate some plant extract(s) rich with BACs produced by conventional extraction. This approach implies negative thermal influences on extraction yield and quality with a large expenditure of organic solvents and energy. On the other hand, sustainable extractions, such as microwav…

Health (social science)Novel foodReviewPlant ScienceRaw materiallcsh:Chemical technologyHealth Professions (miscellaneous)Microbiologyfunctional food0404 agricultural biotechnologyFunctional foodAdded valuelcsh:TP1-1185extractbusiness.industryExtraction (chemistry)Industrial scalefood and beverages04 agricultural and veterinary sciencesPulp and paper industry040401 food sciencefunctional food ; extract ; biological active compounds ; innovative technologySupercritical fluidbiological active compoundsFood processingEnvironmental sciencebusinessinnovative technologyFood ScienceFoods
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Is there any novelty on the horizon of heart failure management in internal medicine? The evaluation of body fluid accumulation

2009

Heart Failureheart failure management body fluidBody fluidmedicine.medical_specialtybusiness.industryNoveltymedicine.diseaseBody FluidsDiagnosis DifferentialHeart failureEmergency MedicineInternal MedicinemedicineHumansMedical emergencybusinessIntensive care medicineInternal and Emergency Medicine
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The Sickle and the Piano. A Distant Reading of Work in the Nineteenth Century Romanian Novel

2020

This article conducts a semantic search of The Digital Museum of the Romanian Novel: The 19th Century (MDRR), through which the authors attempt to identify the occurrences of several key concepts for class and labour imagery in the nineteenth-century Romanian novel, such as “muncă” [labour/work], “muncitor” [labourer/worker], “țăran” [peasant], “funcționar” [civil servant], alongside two main words that strikingly point out to a dissemblance of representation of work: “seceră” [sickle] and “pian” [piano]. The authors show that physical work is underrepresented in the Romanian novel between 1844 and 1900, and that novelists prefer to participate to the rise of the novel through representing …

HistoryGeneral Arts and Humanitiesmedia_common.quotation_subjectRomanianPianolcsh:Literature (General)realismGeneral Social Sciencesnineteenth century fictionlcsh:PN1-6790language.human_languageVisual artslabourWork (electrical)workromanian novelReading (process)languagemedia_commonMetacritic Journal for Comparative Studies and Theory
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