Search results for "nuclei"
showing 10 items of 1273 documents
Redox signaling in acute pancreatitis
2015
Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium, cathepsins, pH disorders, autophagy, and cell death, particularly necrosis. This review focuses on the new role of redox signaling in acute pancreatitis. Oxidative stress and redox status are involved in the onset of acute pancreatitis and also in the development of the systemic inflammatory response, being glutathione depletion, xanthine oxidase activation, and thiol oxidation in proteins critical features of the disease in the pancreas. On th…
Transient cortical circuits match spontaneous and sensory-driven activity during development.
2020
At the earliest developmental stages, spontaneous activity synchronizes local and large-scale cortical networks. These networks form the functional template for the establishment of global thalamocortical networks and cortical architecture. The earliest connections are established autonomously. However, activity from the sensory periphery reshapes these circuits as soon as afferents reach the cortex. The early-generated, largely transient neurons of the subplate play a key role in integrating spontaneous and sensory-driven activity. Early pathological conditions—such as hypoxia, inflammation, or exposure to pharmacological compounds—alter spontaneous activity patterns, which subsequently in…
Regular theta-firing neurons in the nucleus incertus during sustained hippocampal activation
2015
This paper describes the existence of theta-coupled neuronal activity in the nucleus incertus (NI). Theta rhythm is relevant for cognitive processes such as spatial navigation and memory processing, and can be recorded in a number of structures related to the hippocampal activation including the NI. Strong evidence supports the role of this tegmental nucleus in neural circuits integrating behavioural activation with the hippocampal theta rhythm. Theta oscillations have been recorded in the local field potential of the NI, highly coupled to the hippocampal waves, although no rhythmical activity has been reported in neurons of this nucleus. The present work analyses the neuronal activity in t…
βDelayed γRay spectroscopy of heavy neutron rich nuclei “south” of lead
2009
Relativistic projectile fragmentation of a 208Pb primary beam has been used to produce neutron-rich nuclei with proton-holes relative to the Z = 82 shell closure, i.e., “south” of Pb. βDelayed γRay spectroscopy allows to investigate the structural properties of such nuclei with A ~ 195 → 205. The current work presents transitions de-exciting excited states in 204Au, which are the first spectroscopic information on this N = 125 isotone. Agramunt Ros, Jorge, Jorge.Agramunt@ific.uv.es ; Algora, Alejandro, Alejandro.Algora@ific.uv.es ; Molina Palacios, Francisco Manuel, Francisco.Molina@ific.uv.es ; Rubio Barroso, Berta, Berta.Rubio@ific.uv.es
Precision mass measurements of neutron-rich nuclei between N=50 and 82
2012
Our knowledge of binding energies of neutron-rich nuclei has experienced a major revision during the last five years due to the introduction of Penning-trap based mass measurements. New mass values for nearly 300 nuclides produced in fission with uncertainties of 10 keV or less have become available. The data produced at three Penning trap facilities at Jyvaskyla, CERN-ISOLDE and Argonne cover all isotopic chains from Ni to Pr, except iodine. In this talk some of this data is reviewed and applied using the mass differentials such as two-neutron binding energy and odd-even staggering to probe their sensitivity on changes in nuclear structure and on the strength of the N=82 shell gap and asso…
Disentangling decaying isomers and searching for signatures of collective excitations in β decay
2019
6 pags., 3 figs., 1 tab. -- 27th International Nuclear Physics Conference (INPC2019) 29 July - 2 August 2019, Glasgow, UK
Population of neutron-rich nuclei around 48ca with deep inelastic collisions
2009
The deep inelastic reaction 48Ca+64Ni at 6 MeV/A has been studied using the CLARA–PRISMA setup. Angular distributions for pure elastic scattering and total cross-sections of the most relevant transfer channels have been measured. The experimental results are compared with predictions from a semiclassical model, showing good agreement for the presently analyzed few neutrons transfer channels. The decay of the most intense reaction products has also been studied, giving indications of the population of states with very short lifetimes. Gadea Raga, Andrés, Gadea.Andres@ific.uv.es
NATURAL SELECTION AND THE ORGAN-SPECIFIC DIFFERENTIATION OF HIV-1 V3 HYPERVARIABLE REGION
2004
The existence of organ-specific HIV-1 populations within infected hosts has been studied for many years; nonetheless results reported by different authors are somewhat discrepant. To tackle this problem, we used a population genetics approach to analyze previously published data from the V3 hypervariable region of the envelope env gene. Our results are compatible with a population subdivision by organs in 95% of individuals analyzed at autopsy. In addition, populations infecting the nervous system and testicles clearly appear as differentiated subsets of the so-called macrophage-tropic variants. Liver and kidney may harbor differentiated populations as well. Although it is widely accepted t…
Asymptotic normalization coefficients and continuum coupling in mirror nuclei
2012
Background: An asymptotic normalization coefficient (ANC) characterizes the asymptotic form of a one-nucleon overlap integral required for description of nucleon-removal reactions. Purpose: We investigate the impact of the particle continuum on proton and neutron ANCs for mirror systems from $p$- and $sd$-shell regions. Method: We use the real-energy and complex-energy continuum shell model approaches. Results: We studied the general structure of the single-particle ANCs as a function of the binding energy and orbital angular momentum. We computed ANCs in mirror nuclei for different physical situations, including capture reactions to weakly-bound and unbound states. Conclusions: We demonstr…
Neutron-proton pairing correlations in a single l-shell model
2017
The long standing problem of neutron-proton pairing correlations is revisited by employing the Hartree-Fock-Bogoliubov formalism with neutron-proton mixing in both the particle-hole and particle-hole channels. We compare numerical calculations performed within this method with an exact pairing model based on the $SO(8)$ algebra. The neutron-proton mixing is included in our calculations by performing rotations in the isospin space using the isocranking technique.