Search results for "nuclide"
showing 10 items of 397 documents
Maturation of a Key Resource – The Germanium-68/Gallium-68 Generator: Development and New Insights
2011
(68)Ge/(68)Ga radionuclide generators have been investigated for almost fifty years, since the cyclotron-independent availability of positron emitting (68)Ga via the (68)Ge/(68)Ga system had always attracted researches working in basic nuclear chemistry as well as radiopharmaceutical chemistry. However, it took decades and generations of research (and researchers) to finally reach a level of (68)Ge/(68)Ga radionuclide generator designs adequate to the modern requirements of radiometal labelling chemistry. Nevertheless, most of the existing commercial generator systems address aspects of (68)Ge breakthrough and safe synthesis of (68)Ga radiopharmaceuticals by adopting eluate post-processing …
Intrinsic backgrounds from Rn and Kr in the XENON100 experiment
2018
In this paper, we describe the XENON100 data analyses used to assess the target-intrinsic background sources radon ([InlineMediaObject not available: see fulltext.]), thoron ([InlineMediaObject not available: see fulltext.]) and krypton ([InlineMediaObject not available: see fulltext.]). We detail the event selections of high-energy alpha particles and decay-specific delayed coincidences. We derive distributions of the individual radionuclides inside the detector and quantify their abundances during the main three science runs of the experiment over a period of ∼4years, from January 2010 to January 2014. We compare our results to external measurements of radon emanation and krypton concentr…
A no-carrier-added 72Se/72As radionuclide generator based on distillation
2004
Abstract Arsenic-72 is a positron emitting isotope with promising properties for syntheses of 72As-labelled radiopharmaceuticals for future application in positron emission tomography. This work describes the radiochemical separation of no-carrier-added 72Se from cyclotron irradiated germanium targets and the development of a 72Se/72As radionuclide generator, avoiding the addition of any selenium carrier. Using a vertical quartz tube device, no-carrier-added 72As is nearly quantitatively released from various chloride salt solutions containing 72Se within 10 min at a temperature of 100 °C in an HCl gas flow. The kinetics of the 72Se/72As isotope generator has been studied in relation to tem…
A distinct section of the early bronze age society? Stable isotope investigations of burials in settlement pits and multiple inhumations of the Úněti…
2015
OBJECTIVES: Inhumations in so-called settlement pits and multiple interments are subordinate burial practices of the Early Bronze Age Unětice culture in central Germany (2200-1700/1650 BC). The majority of the Unětice population was entombed as single inhumations in rectangular grave pits with a normative position of the body. The goal of the study was to test archaeological hypotheses that the deviant burials may represent socially distinct or nonlocal individuals. MATERIALS AND METHODS: The study comprised up to two teeth and one bone each of 74 human individuals from eight sites and faunal comparative samples. The inhumations included regular, deviant burials in so-called settlement or s…
Analysis of radionuclide concentration in air released through the stack of a radiopharmaceutical production facility based on a medical cyclotron
2015
Abstract Positron emitting radionuclides are increasingly used in medical diagnostics and the number of radiopharmaceutical production facilities have been estimated to be growing worldwide. During the process of production and/or patient administration of radiopharmaceuticals, an amount of these radionuclides might become airborne and escape into the environment. Therefore, the analysis of radionuclide concentration in the air released to the stack is a very important issue to evaluate the dose to the population living around the plant. To this end, sampling and measurement of radionuclide concentration in air released through the stack of a Nuclear Medicine Center (NMC), provided with a c…
Somatostatin and Somatostatin Receptors: From Signaling to Clinical Applications in Neuroendocrine Neoplasms
2021
Neuroendocrine neoplasms (NENs) are heterogeneous neoplasms which arise from neuroendocrine cells that are distributed widely throughout the body. Although heterogenous, many of them share their ability to overexpress somatostatin receptors (SSTR) on their cell surface. Due to this, SSTR and somatostatin have been a large subject of interest in the discovery of potential biomarkers and treatment options for the disease. The aim of this review is to describe the molecular characteristics of somatostatin and somatostatin receptors and its application in diagnosis and therapy on patients with NENs as well as the use in the near future of somatostatin antagonists.
Antarctic erosion history reconstructed by Terre Adélie moraine geochronology
2020
AbstractWe report apatite fission-track and 10Be terrestrial cosmogenic nuclide (TCN) dating of 14 moraine boulders originating from inland Terre Adélie, East Antarctica. These data show cooling of the Proterozoic Terre Adélie craton at < ~120°C between 350 and 300 Ma, suggesting > 4 km temperate glacial erosion during the Late Palaeozoic Ice Age, followed by nearly null Mesozoic erosion and low glacial erosion (< 2 km) in the Cenozoic. Based on glacial flux maps, the origin of the boulders may be located ~400 km upstream. Preliminary TCN (10Be) datings of moraine boulders cluster within the last 30 ka. Cosmogenic ages from the Lacroix Nunatak suggest a main deglaciation after the …
Mediterranean Tertiary lamproites derived from multiple source components in postcollisional geodynamics
2008
Abstract In the Mediterranean area, lamproitic provinces in Spain, Italy, Serbia and Macedonia have uniform geological, geochemical and petrographic characteristics. Mediterranean lamproites are SiO2-rich lamproites, characterized by relatively low CaO, Al2O3 and Na2O, and high K2O/Al2O3 and Mg-number. They are enriched in LILE relative to HFSE and in Pb, and show depletion in Ti, Nb and Ta. Mediterranean lamproites show huge regional variation of Sr, Nd and 207Pb/204Pb isotopic values, with 87Sr/86Sr range of 0.707–0.722, eNd range from −13 to −3, and 207Pb/204Pb range of 15.62–15.79. Lamproitic rocks are derived from melts with three components involved in their origin, characterized by c…
Orogenic vs anorogenic lamproites in a single volcanicprovince: Mediterranean-type lamproites from Turkey
2008
Lamproites are mantle-derived ultrapotassic volcanic rocks, derived from phlogopite-bearing harzburgitic source. The origin of the metasomatism which enriched their mantle source is either an old event with a metasomatic component derived from the convecting mantle, or is a more recent introduction of an already aged metasomatic component. Together with different trace element signatures, this view serves for a general distinction between anorogenic and orogenic lamproites worldwide. In Turkey, lamproitic volcanism resulted from interplay of subduction/collisional and postcollisional/extensional regime since Miocene until Pliocene, in the Western Anatolia-Aegean and Kirka-Afyon-Isparta regi…
Improved discrimination of subglacial and periglacial erosion using10Be concentration measurements in subglacial and supraglacial sediment load of th…
2015
Deciphering the complex interplays between climate, uplift and erosion is not straightforward and estimating present-day erosion rates can provide useful insights. Glaciers are thought to be powerful erosional agents, but most published ‘glacial’ erosion rates combine periglacial, subglacial and proglacial erosion processes. Within a glaciated catchment, sediments found in subglacial streams originate either from glacial erosion of substratum or from the rock walls above the glacier that contribute to the supraglacial load. Terrestrial cosmogenic nuclides (TCN) are produced by interactions between cosmic ray particles and element targets at the surface of the Earth, but their concentration …