Search results for "oak"
showing 10 items of 181 documents
Efficient Consecutive Synthesis of Ethyl-2-(4-Aminophenoxy) Acetate, a Precursor for Dual GK and PPARγ Activators, X-ray Structure, Hirshfeld Analysi…
2022
Herein, we report a facile synthesis of ethyl-2-(4-aminophenoxy)acetate 4 as a building synthon for novel dual hypoglycemic agents. This building template was synthesized by alkylation of 4-nitrophenol with ethyl bromo-acetate followed by selective reduction of the nitro group. This reduction methoddoes not require nascent hydrogen or any reaction complexity; it goes easily via consecutive reaction in NH4Cl/Fe to yield our target synthon as very pure crystals. This product was characterized by 1HNMR, 13CNMR, COSY, NOESY NMR spectroscopy, and elemental analysis. Additionally, its structure was studied and approved by X-ray single crystal structure determination. The unit cell parameters are …
Anomalous performance enhancement effects in Ruthenium-based Dye Sensitized Solar Cells
2017
Dye Sensitized Solar Cells (DSSCs) are nowadays more and more employed since they present lower production costs than traditional silicon photovoltaic devices. An interesting phenomenon affecting such devices consists in the fact that current density-voltage (J-V) characteristic can depend on the history of the cell prior to the measurement, which often can be assimilated to an anomalous hysteresis effect. In this work, we study such phenomenon on Ruthenium-based DSSCs through a series of measurements performed after applying different values of external electrical field to the cell. The measurements have been carried out both under simulated sunlight (AM1.5G - 1000 W/m2) and in the dark. W…
Radioactivity control strategy for the JUNO detector
2021
JUNO is a massive liquid scintillator detector with a primary scientific goal of determining the neutrino mass ordering by studying the oscillated anti-neutrino flux coming from two nuclear power plants at 53 km distance. The expected signal anti-neutrino interaction rate is only 60 counts per day (cpd), therefore a careful control of the background sources due to radioactivity is critical. In particular, natural radioactivity present in all materials and in the environment represents a serious issue that could impair the sensitivity of the experiment if appropriate countermeasures were not foreseen. In this paper we discuss the background reduction strategies undertaken by the JUNO collabo…
Detailed spectroscopy of the neutron-deficient bismuth isotopes ¹⁹³,¹⁹⁵Bi
2015
Two experiments aiming to study the shape coexistence and competing structures in 193Bi and 195Bi isotopes have been performed at the Accelerator laboratory of the University of Jyv askyl a, Finland (JYFL). Many new states have been found, hugely extending the previously known level schemes for both isotopes. The i13=2 bands were extended up to I = 45/2+ in both the 193;195Bi isotopes. In case of 193Bi, the I = 31/2+ member of the i13=2 band was found to de-excite also to a long-lived isomeric state. This link determines the energy of the isomeric state to be 2350(1) keV and suggests a spin and parity of 29/2+. The half-life of the isomeric state was measured to be 85(3) s. A level structur…
γ decay of excited states in 198Rn identified using correlated radioactive decay
1999
The low-lying level structure of the neutron-deficient isotope 198Rn has been studied for the first time, using the 166Er(36Ar,4n) reaction at a beam energy of 175 MeV. Evaporation residues were selected using an in-flight gas-filled separator, RITU, and implanted at the focal plane into a 16-element position-sensitive, passivated ion-implanted planar silicon detector. Prompt γ rays in 198Rn were observed at the target position using the JUROSPHERE array of 24 Compton-suppressed germanium detectors, and were identified by the subsequent radioactive decay of associated recoiling ions in the silicon detector. Isotopic assignments of the nuclei produced were made on the basis of the energy and…
Interpretation of gut microbiota data in the ‘eye of the beholder’: A commentary and re‐evaluation of data from ‘Impacts of radiation exposure on the…
2021
1.Evidence that exposure to environmental pollutants can alter the gut microbiota composition of wildlife includes studies of rodents exposed to radionuclides. 2.Antwis et al. (2021) used amplicon sequencing to characterise the gut microbiota of four species of rodent (Myodes glareolus, Apodemus agrarius, A. flavicollis and A. sylvaticus) inhabiting the Chernobyl Exclusion Zone (CEZ) to examine possible changes in gut bacteria (microbiota) and gut fungi (mycobiota) associated with exposure to radionuclides and whether the sample type (from caecum or faeces) affected the analysis. 3.The conclusions derived from the analyses of gut mycobiota are based on data that represent a mixture of inges…
Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (…
2022
Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedure for the reaction of β-dicarbonyl compounds (ethylacetoacetate, 5,5-dimethyl-1,3-cyclohexadione or 1,3-cyclohexadionone) with N,N-dimethylformamide dimethylacetal, followed by addition of 2-hydrazinyl-4,6-disubstituted-s-triazine either in ethanol-acetic acid or neat acetic acid to afford a novel pyrazole and pyrazole-fused cycloalkanone systems. The synthetic protocol proved to be efficient, with a shorter reaction time and high chemical yield with broad substrates. The new pyrazolyl-s-triazine derivatives were tested against the following cell lines: MCF-7 (breast cancer); MDA-MB-231 (tr…
Synthesis and biological evaluation of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepine and its cycloalkane and cycloa…
2021
Derivatives of the new ring system benzo[f]pyrimido[1,2-d][1,2,3]triazolo[1,5-a][1,4]diazepinone and its cycloalkane and cycloalkene condensed analogues have been conveniently synthesized through a three-step reaction sequence. An atom-economical, one-pot, three-step cascade process engaging five reactive centers (amide, amine, carbonyl, azide, and alkyne) has been performed for the synthesis of alicyclic derivatives of quinazolinotriazolobenzodiazepine using cyclohexane, cyclohexene, and norbornene β-amino amides. The stereochemistry and relative configurations of the synthesized compounds were determined by 1D and 2D NMR spectroscopy and X-ray crystallography. The reaction was also perfor…
Synthesis, Characterization, and Cytotoxicity of New Spirooxindoles Engrafted Furan Structural Motif as a Potential Anticancer Agent
2022
A new series of spirooxindoles based on ethylene derivatives having furan aryl moiety are reported. The new hybrids were achieved via [3 + 2] cycloaddition reaction as an economic one-step efficient approach. The final constructed spirooxindoles have four contiguous asymmetric carbon centers. The structure of 3a is exclusively confirmed using X-ray single crystal diffraction. The supramolecular structure of 3a is controlled by O···H, H···H, and C···C intermolecular contacts. It includes layered molecules interconnected weak C–H···O (2.675 Å), H···H (2.269 Å), and relatively short Cl···Br interhalogen interactions [3.4500(11)Å]. Using Hirshfeld analysis, the percentages of these intermolecul…