Search results for "observation"

showing 10 items of 1586 documents

Exercise and sport in the treatment of haemophilic patients: a systematic review

2008

Summary. In haemophiliacs, the physical condition, muscular strength, aerobic resistance, anaerobic resistance and proprioception have all diminished. Muscle atrophy and instability, being more vulnerable to stressful motor demands, increase the risk of lesion and establish a vicious circle that is hard to break: pain, immobility, atrophy, articular instability and repeated bleeding episodes. In haemophilia, physical and/or sporting activities were not recommended until the seventies. Nowadays, the overall policy is to recommend certain physical activities, especially swimming, to improve the patients quality of life, thanks to prophylaxis programmes. The objective of this study is to perfo…

Malemedicine.medical_specialtymedicine.medical_treatmentCINAHLHemophilia APhysical strengthHaemophiliaAtrophyPhysical medicine and rehabilitationQuality of lifeHemarthrosisHumansMedicineExercisePhysical Therapy ModalitiesGenetics (clinical)Rehabilitationbusiness.industryHematologyGeneral Medicinemedicine.diseasePhysical therapyObservational studybusinessAnaerobic exerciseSportsHaemophilia
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Decreased postural control in people with moderate hearing loss

2018

Balance is a complex process that involves multiple sensory integrations. The auditory, visual, and vestibular systems are the main contributors. Hearing loss or hearing impairment may induce inappropriate postural strategies that could affect balance and therefore increase the risk of falling. The aim of this study was to understand whether hearing loss could influence balance, cervical posture, and muscle activation in the cervical region. Thirteen patients (61 ± 13 years; 161.8 ± 11.0 cm; 70.5 ± 15.9 kg) with moderate hearing loss (Right ear −60 ± 21 dB; Left ear −61 ± 24 dB) underwent: an audiometric examination, a postural examination (with open and closed eyes) through a stabilometric…

Malemedicine.medical_specialtyrange of movementHearing lossfallPostureObservational StudySensory system7000ElectromyographyAudiologyPostural control03 medical and health sciences0302 clinical medicineEMGAudiometryfallsAccelerometrymedicineotorhinolaryngologic diseasesHumans030212 general & internal medicineHearing LossPostural BalanceBalance (ability)AgedVestibular systemCross-Sectional Studiemedicine.diagnostic_testbusiness.industryElectromyographyGeneral Medicinehearing loMiddle AgedSagittal planeEMG; falls; hearing loss; posture; range of movement; Accelerometry; Aged; Audiometry; Cross-Sectional Studies; Electromyography; Female; Head; Hearing Loss; Humans; Male; Middle Aged; Neck; Postural Balance; Posturemedicine.anatomical_structureCross-Sectional StudiesFemalemedicine.symptombusinessFalling (sensation)Head030217 neurology & neurosurgeryNeckResearch ArticleHuman
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Patient-centered and clinical outcomes of mandibular overdentures retained with the locator system: A prospective observational study

2017

Whether clinical or demographic variables affect the perception of treatment in terms of quality of life and satisfaction is unknown.The purpose of this prospective study was to make an evidence-based assessment of the treatment outcomes (patient- and clinically based) of locator-retained mandibular overdentures.This prospective observational study assessed patients with edentulism who had worn mandibular overdentures supported by 2 implants and retained by the locator system for at least 1 year of functional life (N=80). Medical histories were reviewed, and patients underwent oral examinations. Prosthetic clinical outcomes and patient well-being were registered using the Oral Health Impact…

Malemedicine.medical_treatmentDenture Complete LowerDentistryOral HealthMandibleAffect (psychology)Prosthesis03 medical and health sciences0302 clinical medicinePatient satisfactionQuality of lifeSurveys and QuestionnairesDenture RebasingHumansJaw EdentulousMedicineProspective StudiesDenture DesignProspective cohort studySurvival analysisAgedDental ImplantsEdentulismbusiness.industry030206 dentistryDenture Overlaymedicine.diseaseDenture RetentionSurvival Analysisstomatognathic diseasesTreatment OutcomePatient SatisfactionSpainQuality of LifeFemaleObservational studyDental Prosthesis Implant-SupportedOral Surgerybusiness030217 neurology & neurosurgeryFollow-Up StudiesThe Journal of Prosthetic Dentistry
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Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease

2021

OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need fo…

Malemedicine.medical_treatmentpulmonary complicationsRESPIRATORY-DISTRESS-SYNDROMECritical Care and Intensive Care MedicineCASE-FATALITY0302 clinical medicineRisk FactorsBrain Injuries TraumaticMulticenter Studies as TopicHospital MortalityProspective StudiesSimplified Acute Physiology ScoreStrokePOPULATIONSimplified Acute Physiology ScoreAge FactorsANEURYSMAL SUBARACHNOID HEMORRHAGEMiddle AgedHemorrhagic StrokeIntensive Care UnitsObservational Studies as TopicAnesthesiaBreathingFemalemedicine.symptomVentilator WeaningCohort studyAdultTRAUMATIC BRAIN-INJURYPressure support ventilationmechanical ventilationprognosis factorsACUTE LUNG INJURY03 medical and health sciencesmedicineHumansAgedIschemic StrokeMechanical ventilationNoninvasive Ventilationbusiness.industryMORTALITYneurologic patientsOrgan dysfunction030208 emergency & critical care medicineLength of Staymedicine.diseaseTRENDSRespiration Artificial030228 respiratory systemEtiologyNEUROCRITICAL CARENervous System DiseasesTracheotomybusinessCritical Care Medicine
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Injectable Versus Oral First-Line Disease-Modifying Therapies: Results from the Italian MS Register

2021

AbstractThe current study aims to compare injectable and oral first-line disease-modifying therapies (DMTs) for time to first relapse, time to confirmed disability progression (CDP), and time to discontinuation using a cohort of relapsing remitting multiple sclerosis (RRMS) patients, with data extracted from the Italian MS Register. This multicenter, observational, retrospectively acquired, and propensity-adjusted cohort study utilized RRMS-naïve patients from the Italian MS Register who started either injectable or oral first-line DMTs between January 1, 2010, and December 31, 2017, to evaluate the impact on disability outcomes in patients. Enrolled patients were divided into two groups, n…

Maleoral DMTsoral DMTAdministration OralDiseaseRelapsing-RemittingCohort Studies0302 clinical medicineImmunologicinjectable DMTPharmacology (medical)030212 general & internal medicineRegistriesSubcutaneousMiddle AgedItalyEDSS score; injectable DMTs; Multiple sclerosis; oral DMTs; real-world setting; Adjuvants Immunologic; Administration Oral; Adult; Cohort Studies; Female; Follow-Up Studies; Glatiramer Acetate; Humans; Immunologic Factors; Injections Subcutaneous; Interferon-beta; Italy; Male; Middle Aged; Multiple Sclerosis Relapsing-Remitting; Retrospective Studies; RegistriesAdministrationCohortSettore MED/26 - NeurologiaOriginal ArticleFemaleNeurosurgeryCohort studyOralAdultmedicine.medical_specialtyEDSS scoreInjections SubcutaneousLower riskInjectionsMultiple sclerosis03 medical and health sciencesMultiple Sclerosis Relapsing-RemittingAdjuvants ImmunologicInternal medicinereal-world settingmedicineHumansImmunologic FactorsMultiple sclerosiAdjuvantsinjectable DMTsRetrospective StudiesPharmacologybusiness.industryMultiple sclerosisGlatiramer AcetateInterferon-betamedicine.diseaseDiscontinuationObservational studyNeurology (clinical)business030217 neurology & neurosurgeryFollow-Up Studies
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Drug‐refractory myasthenia gravis: Clinical characteristics, treatments, and outcome

2022

[Objective] To describe the clinical characteristics and outcomes in patients with refractory myasthenia gravis (MG) and to determine the effectiveness and side effects of the drugs used for their treatment.

Maleprogressive multifocal leukoencepdiarrheacholinergic receptorplasma exchangemiddle agedadultimmunologic factornauseaanemiahypertrichosisageddrug withdrawaldiabetes mellitusdisease severityTRIALsafetycorticosteroidhypertensionImmunologyMiastenia gravismethotrexateArticlebulbar paralysispancytopeniaMuscular DiseasescompulsionMyasthenia Gravischolinesterase inhibitorcross-sectional studyHumansImmunologic FactorshumanRITUXIMABarthralgiaNeurologíaMalalties muscularsAgedRetrospective Studiesmyasthenia gravisleukopeniaabdominal painDrug testingmajor clinical studyCross-Sectional StudiesDrug side effectscyclophosphamideobservational studyNeurology (clinical)immunoglobulinFEATURESefficacyclinical outcomeelectrophysiological procedurescomputer assisted tomographyDOUBLE-BLINDTratamiento médicorituximabOutcome Assessment Health CareImmunologiamuscle specific tyrosine kinaseRegistriestacrolimusazathioprineMedicamentoGeneral Neurosciencenephrotoxicitygeneral condition deteriorationhyperplasiatrialMiddle Agedliver toxicitydrug toxicityunclassified drugfemaleEfectes secundaris dels medicamentsSAFETYFemaledouble-blindheadacheblindnessAdultAssaigs clínics de medicamentsmalefeaturesfollow uppneumoniacyclosporinemycophenolate mofetilprotein tyrosine kinaseimmunosuppressive agentallergyalopeciaEFFICACYclinical featureosteopeniaSpainprednisonehyperglycemiaautoantibodyFollow-Up Studies
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Impact of tiotropium + olodaterol on physical functioning in COPD: results of an open-label observational study

2016

Rüdiger Sauer,1 Michaela Hänsel,2 Roland Buhl,3 Roman A Rubin,4 Marcel Frey,5 Thomas Glaab2,3 1Lung Centre Ulm, Ulm, Germany; 2Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany; 3Pulmonary Department, Mainz University Hospital, Mainz, Germany; 4Pulmonary Specialist Practice, Wiesbaden, Germany; 5Biometrics, Alcedis GmbH, Gießen, Germany Background: Maintaining and improving physical functioning is key to mitigating the cycle of deconditioning associated with chronic obstructive pulmonary disease (COPD). We evaluated the impact of free combination of the long-acting anticholinergic tiotropium plus the long-acting β2-agonist ol…

Malereal-worldTime FactorsnoninterventionalHealth StatusSeverity of Illness IndexCholinergic AntagonistsPulmonary Disease Chronic Obstructivechemistry.chemical_compound0302 clinical medicinetiotropiumDeconditioningPhysical functioningSurveys and QuestionnairesProspective Studies030212 general & internal medicineLungOriginal ResearchCOPDOlodaterolGeneral MedicineTiotropium bromideMiddle AgedBronchodilator AgentsDrug CombinationsTreatment OutcomeFemalemedicine.drugmedicine.medical_specialtymedicine.drug_classInternational Journal of Chronic Obstructive Pulmonary Diseasechronic obstructive pulmonary disease03 medical and health sciencesAdministration InhalationSeverity of illnessmedicineAnticholinergicphysical functioningHumansTiotropium BromideIntensive care medicineAdrenergic beta-2 Receptor AgonistsAgedolodaterolbusiness.industryNebulizers and VaporizersRecovery of Functionmedicine.diseaseBenzoxazines030228 respiratory systemchemistryPhysical therapyObservational studybusinessInternational Journal of Chronic Obstructive Pulmonary Disease
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Predicting domain-specific actions in expert table tennis players activates the semantic brain network.

2018

Motor expertise acquired during long-term training in sports enables top athletes to predict the outcomes of domain-specific actions better than nonexperts do. However, whether expert players encode actions, in addition to the concrete sensorimotor level, also at a more abstract, conceptual level, remains unclear. The present study manipulated the congruence between body kinematics and the subsequent ball trajectory in videos of an expert player performing table tennis serves. By using functional magnetic resonance imaging, the brain activity was evaluated in expert and nonexpert table tennis players during their predictions on the fate of the ball trajectory in congruent versus incongruent…

Malesemantic expectationBrain activity and meditationMiddle temporal gyruspeilisolutaction observationtoiminnallinen magneettikuvaus0302 clinical medicinehavainnointiSemantic memoryMirror neuronCerebral CortexBrain Mappingmedicine.diagnostic_test05 social sciencesMagnetic Resonance ImagingBiomechanical PhenomenaSemanticsmedicine.anatomical_structureNeurologytable tennis playerVisual PerceptionFemalemirror neuron systemSensorimotor CortexPsychologyCognitive psychologyAdultCognitive NeuroscienceVentromedial prefrontal cortex050105 experimental psychologyAngular gyrus03 medical and health sciencesYoung AdultpelaajatmedicineHumans0501 psychology and cognitive sciencesaction anticipationennakointiMirror NeuronsRacquet SportspöytätennisAnticipation Psychologicalfunctional magnetic resonance imagingAction observationNerve NetFunctional magnetic resonance imaginghuman activities030217 neurology & neurosurgeryPsychomotor PerformanceNeuroImage
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Teacher-student interaction and lower secondary school students’ situational engagement

2018

BACKGROUND Prior research has shown that engagement plays a significant role in students' academic learning. AIMS The present study sought to expand the current understanding of students' engagement by examining how situational engagement during a particular lesson is associated with the observed teacher-student classroom interactions (i.e., emotional support, instructional support, and classroom organization) in the same lesson. SAMPLE The participants were 709 Grade 7 students (47.7% girls) from 59 classrooms in 26 lower secondary schools and 51 teachers. METHODS The data consisted of 155 video-recorded lessons (90 language arts and 65 mathematics lessons) coded using the Classroom Assess…

Maleteacher–student interactionAdolescentAcademic learningAcademic achievementluokkatyöskentelyEducationComputingMilieux_COMPUTERSANDEDUCATIONDevelopmental and Educational PsychologyMathematics educationHumans0501 psychology and cognitive sciencesInterpersonal Relationsta516situational engagementSituational ethicsStudentslower secondary schoolopettaja-oppilassuhdeta515Class (computer programming)Language artsSchools4. Education05 social sciences050301 educationSocial SupportsitoutuminenHelp-seekingEmotional engagementobservationsAdolescent BehaviorObservational studyFemaleSchool TeachersyläkouluPsychology0503 education050104 developmental & child psychologyFollow-Up StudiesBritish Journal of Educational Psychology
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Safety of endovascular treatment in acute stroke patients taking oral anticoagulants

2017

International journal of stroke 12(4), 412-415 (2017). doi:10.1177/1747493016677986

Maletherapeutic use [Anticoagulants]medicine.medical_specialtyMedizinAdministration Oral030204 cardiovascular system & hematologyBrain IschemiaBrain ischemia03 medical and health sciences0302 clinical medicineetiology [Intracranial Hemorrhages]Modified Rankin ScaleInterquartile rangeAntithromboticmedicineHumansThrombolytic Therapyddc:610Prospective StudiesRegistriesadverse effects [Anticoagulants]Prospective cohort studyStrokeAgedAged 80 and overbusiness.industryConfoundingAnticoagulantsmethods [Thrombolytic Therapy]complications [Brain Ischemia]Middle Agedmedicine.diseasedrug therapy [Stroke]Surgerysurgery [Stroke]StrokeTreatment Outcomeadministration & dosage [Anticoagulants]Neurologydrug therapy [Brain Ischemia]FemaleObservational studydrug therapy [Intracranial Hemorrhages]businessIntracranial Hemorrhages030217 neurology & neurosurgery
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