Search results for "observation"
showing 10 items of 1586 documents
Related versus unrelated donor transplantation for high risk (HiRi) acute myeloid leukemia (AML) in first complete remission (CR1)
2007
Abstract Allogeneic hematopoietic stem cell transplantation (allo-SCT) from an HLA-identical sibling donor (SIB) is considered the preferred postremission therapy for younger patients with HiRi AML in CR1. The role of allo-SCT from volunteer unrelated donors (VUDs) is less clear and randomized controlled trials addressing this issue do not exist. We performed an observational landmark analysis on parallel cohorts of patients aged <60 years with AML in CR1 and HiRi cytogenetics who had been enrolled into the AML Cooperative Group (AMLCG) 1999 trial. 2347 patients were evaluable for the present update. 243/2347 patients were <60 years of age and had unfavorable cytogenetics [com…
Tea Consumption and Risk of Cancer
2020
Tea is one of the most widely consumed beverages, but its association with cancer risk remains controversial and unclear. We performed an umbrella review to clarify and determine the associations between tea consumption and various types of cancer by summarizing and recalculating the existing meta-analyses. Meta-analyses of observational studies reporting associations between tea consumption and cancer risk were searched on PubMed and Embase. Associations found to be statistically significant were further classified into levels of evidence (convincing, suggestive, or weak), based on P value, between-study heterogeneity, prediction intervals, and small study effects. Sixty-four observational…
Virtual Clinical and Precision Medicine Tumor Boards-Cloud-Based Platform-Mediated Implementation of Multidisciplinary Reviews Among Oncology Centers…
2021
Background Multidisciplinary tumor boards play a pivotal role in the patient-centered clinical management and in the decision-making process to provide best evidence-based, diagnostic, and therapeutic care to patients with cancer. Among the barriers to achieve an efficient multidisciplinary tumor board, lack of time and geographical distance play a major role. Therefore, the elaboration of an efficient virtual multidisciplinary tumor board (VMTB) is a key point to successfully obtain an oncology team and implement a network among health professionals and institutions. This need is stronger than ever during the COVID-19 pandemic. Objective This paper presents a research protocol for an obse…
The Relevance of Online Social Relationships Among the Elderly: How Using the Web Could Enhance Quality of Life?
2020
This observational study analyzes the impact of Internet use on the quality of life and well-being of the elderly. Specifically, it seeks to understand and clarify the effects of Internet use on relationships in terms of self-esteem, life satisfaction, and Online and Offline Social Support in a sample of senior and elderly Italian people (over 60 years of age). A cohort of 271 elderly people (133 males and 138 females) aged between 60 and 94 years old participated in the study: 236 were Internet Users while the other 35 were Non-Internet Users. The results showed that the time elderly people spend online has a negative effect on their perception of Offline Social Support (Offline Emotional …
Mapping accretion variability in NGC 2264
2014
Our study aims at characterizing the accretion properties of several hundred members of the star-forming region NGC 2264 (3Myr). We performed a deep u,g,r,i mapping of the cluster with CFHT/MegaCam, and monitored the simultaneous u+r variability of its members over a baseline of two weeks. Stellar parameters are determined homogeneously for about 750 monitored young objects, 40% of which are accreting T Tauri stars. Accretion properties and accretion variability are investigated and characterized from UV excess measurements. Non-accreting members of the cluster define the reference UV emission level over which flux excess is detected and measured. Cone search capability for table J/A+A/570/…
X-ray sources in NGC 752
2008
While observational evidence shows that most of the decline in a star's X-ray activity occurs between the age of the Hyades (~8x10^8yr) and that of the Sun, very little is known about the evolution of stellar activity between these ages. To gain information on the typical level of coronal activity at a star's intermediate age, we studied the X-ray emission from stars in the 1.9Gyr old open cluster NGC 752. We analysed a ~140ks Chandraobservation of NGC 752 and a ~50ks XMM-Newtonobservation of the same cluster. We detected 262 X-ray sources in the Chandra data and 145 sources in the XMM-Newton observation. Around 90% of the catalogued cluster members within Chandra's field-of-view are detect…
Gamma Vel cluster membership and IMF
2016
Understanding the properties of young open clusters, such as the Initial Mass Function (IMF), star formation history and dynamic evolution, is crucial to obtain reliable theoretical predictions of the mechanisms involved in the star formation process. We want to obtain a list, as complete as possible, of confirmed members of the young open cluster Gamma Velorum, with the aim of deriving general cluster properties such as the IMF. We used all available spectroscopic membership indicators within the Gaia-ESO public archive together with literature photometry and X-ray data and, for each method, we derived the most complete list of candidate cluster members. Then, we considered photometry, gra…
Acoustic and optical variations during rapid downward motion episodes in the deep north-western Mediterranean Sea
2011
An Acoustic Doppler Current Profiler (ADCP) was moored at the deep-sea site of the ANTARES neutrino telescope near Toulon, France, thus providing a unique opportunity to compare high-resolution acoustic and optical observations between 70 and 170 m above the sea bed at 2475 m. The ADCP measured downward vertical currents of magnitudes up to 0.03 m s-1 in late winter and early spring 2006. In the same period, observations were made of enhanced levels of acoustic reflection, interpreted as suspended particles including zooplankton, by a factor of about 10 and of horizontal currents reaching 0.35 m s-1. These observations coincided with high light levels detected by the telescope, interpreted …
The ANTARES telescope neutrino alert system
2012
The ANTARES telescope has the capability to detect neutrinos produced in astrophysical transient sources. Potential sources include gamma-ray bursts, core collapse supernovae, and flaring active galactic nuclei. To enhance the sensitivity of ANTARES to such sources, a new detection method based on coincident observations of neutrinos and optical signals has been developed. A fast online muon track reconstruction is used to trigger a network of small automatic optical telescopes. Such alerts are generated for special events, such as two or more neutrinos, coincident in time and direction, or single neutrinos of very high energy.
Fluorescence explorer (FLEX): An optimised payload to map vegetation photosynthesis from space
2006
The FLuorescence EXplorer (FLEX) mission proposes to launch a satellite for the global monitoring of steady-state chlorophyll fluorescence in terrestrial vegetation. Fluorescence is a sensitive probe of photosynthetic function in both healthy and physiologically perturbed vegetation, and a powerful non-invasive tool to track the status, resilience, and recovery of photochemical processes and moreover provides important information on overall photosynthetic performance with implications for related carbon sequestration. The early responsiveness of fluorescence to atmospheric, soil and plant water balance, as well as to atmospheric chemistry and human intervention in land usage makes it an ob…