Search results for "observational study"

showing 6 items of 776 documents

Omalizumab outcomes for up to 6 years in pediatric patients with severe persistent allergic asthma

2021

BACKGROUND: Various studies have assessed omalizumab outcomes in the clinical practice setting but follow-up and/or number of patients included were limited. We aim to describe the long-term outcomes of pediatric patients with severe persistent allergic asthma receiving omalizumab in the largest real-life cohort reported to date. METHODS: ANCHORS was a multicenter, observational, retrospective cohort study conducted in 25 Pediatric Allergy and Pulmonology units in Spain. We collected data of patients < 18 years and initiating omalizumab between 2006 and 2018, from the year prior to omalizumab initiation to discontinuation or last available follow-up. The primary outcome was the evolution of…

severe asthmamedicine.medical_specialtyPediatricsImmunology*real lifeOmalizumabhumanized monoclonal antibodiesOmalizumab*adolescentsAntibodies Monoclonal HumanizedAnti-asthmatic Agent03 medical and health sciences0302 clinical medicinechildrenreal lifeInternal medicinemedicine*anti-asthmatic agents*childrenHumansImmunology and AllergyChildren adolescents anti-asthmatic agents humanized monoclonal antibodies observational study omalizumab real-life severe asthmaAnti-Asthmatic Agentsadolescents030212 general & internal medicineChildAdverse effectRetrospective Studiesbusiness.industryasthmatic agents*observational studyanti&#8208Retrospective cohort studyAsthmaDiscontinuation*omalizumabTreatment OutcomePulmonology030228 respiratory system*humanized monoclonal antibodies*severe asthmaSevere persistent allergic asthmaPediatrics Perinatology and Child HealthCohortomalizumabobservational studyObservational studybusinessmedicine.drugPediatric Allergy and Immunology
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bbFISH-ing in the sonication fluid

2019

Abstract By 2030, the annual number of combined total hip and knee arthroplasty is estimated to reach 3.5 to 4 million in the US alone. In the context of a constant increase of the number of primary and revision total hip and knee arthroplasty, an increased risk of complication is expected. Prosthetic joint infections (PJIs) represent major cause of healthcare expenditure and morbidity. PJI still remain the most common and feared arthroplasty complication. A rapid and correct diagnosis of infection is decisive for a correct therapeutical management. In this setting, the Academic Emergency Hospital Sibiu adopted and implemented, with the beginning of September 2016, a new strategy for the di…

sonicationMaleProsthetic joint infectionmedicine.medical_specialtyPJIProsthesis-Related InfectionsArthroplasty Replacement Hipmedicine.medical_treatmentSonication7100Observational StudydiagnosticContext (language use)biofilm03 medical and health sciences0302 clinical medicineStaphylococcus epidermidisRNA Ribosomal 16SInternal medicineSynovial FluidmedicineHumans030212 general & internal medicineArthroplasty Replacement KneeIn Situ Hybridization FluorescenceAgedAged 80 and overBacteriological Techniquesbiologybusiness.industryRalstonia pickettiimolecular diagnosticBacterial InfectionsGeneral MedicineGold standard (test)Middle Agedbiology.organism_classificationArthroplastyRNA BacterialConnective Tissue030220 oncology & carcinogenesisPositive culturebbFISHFemaleComplicationbusinessResearch ArticleMedicine
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Quality of educational dialogue and association with students’ academic performance

2018

The study used a mixed-methods approach to examine the associations between the quality of educational dialogue and students' academic performance and to analyse what kinds of dialogic teaching patterns of different levels of quality can be identified in classroom lessons. A total of 158 Grade 6 lessons were video-recorded, and the quality of the educational dialogue was assessed using the Classroom Assessment Scoring System-Secondary (CLASS-S) observational instrument. Multilevel modelling indicated that the quality of educational dialogue was positively associated with students’ academic performance (grades) in language arts and physics/chemistry. Qualitative analysis was subsequently use…

teacher-initiatedmedia_common.quotation_subjectstudent-initiatedEducationdialogiQualitative analysisPedagogyDevelopmental and Educational PsychologyMathematics educationComputingMilieux_COMPUTERSANDEDUCATIONta5160501 psychology and cognitive sciencesQuality (business)Chemistry (relationship)Association (psychology)opettaja-oppilassuhdemedia_commonLanguage artsClass (computer programming)Dialogiceducational dialogue05 social sciencesteacher-student interactionsacademic performance050301 educationObservational studyPsychology0503 education050104 developmental & child psychology
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Observed Classroom Quality Profiles of Kindergarten Classrooms in Finland

2012

Research Findings: The aim of the present study was to examine classroom quality profiles of kindergarten classrooms using a person-centered approach and to analyze these patterns in regard to teacher and classroom characteristics. Observations of the domains of Emotional Support, Classroom Organization, and Instructional Support were conducted in 49 Finnish kindergarten classrooms utilizing the Classroom Assessment Scoring System (R. C. Pianta, K. M. LaParo, & B. K. Hamre, 2008 ). In addition, questionnaire data on classroom and teacher characteristics, as well as Early Childhood Classroom Observation Measure (D. Stipek & P. Byler, 2004 ) observational ratings, were used in the analyses. L…

teaching practicesEarly childhood educationmedia_common.quotation_subjectTeaching methodluokkahuoneen laatuclassroom qualityesiopetusResearch findingsohjauskäytänteetLiteracyEducationInter-rater reliabilityDevelopmental and Educational PsychologyMathematics educationProfiling (information science)kindergartenObservational studyQuality (business)ta516Psychologymedia_commonEarly Education and Development
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Zero-Heat-Flux and Esophageal Temperature Monitoring in Orthopedic Surgery: An Observational Study

2021

Judy Munday,1,2 Niall Higgins,1,3 Lee Jones,1,4 Dimitrios Vagenas,4 André Van Zundert,1,5,6 Samantha Keogh1,3 1School of Nursing &amp; Centre for Healthcare Transformation, Faculty of Health, Queensland University of Technology, Kelvin Grove, QLD, Australia; 2Department of Health and Nursing Science, Faculty of Health and Sports Sciences, University of Agder, Grimstad, Norway; 3Royal Brisbane and Women’s Hospital, Herston, QLD, Australia; 4Research Methods Group, Institute of Health and Biomedical Innovation (IHBI), Faculty of Health, Queensland University of Technology, Kelvin Grove, QLD, Australia; 5Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women’s Hosp…

thermoregulationMeasurement methodmedicine.medical_specialtyEsophageal temperatureTemperature monitoringthermometrybusiness.industryJournal of Multidisciplinary HealthcareConcordancespecificityGeneral MedicinePerioperativesensitivityOrthopedic surgerymedicineObservational studyperioperativeBland–Altman plotNuclear medicinebusinessGeneral NursingOriginal ResearchJournal of Multidisciplinary Healthcare
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Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic rev…

2021

AbstractBackgroundMultiple studies regarding the use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in patients with non-compressible torso injuries and uncontrolled haemorrhagic shock were recently published. To date, the clinical evidence of the efficacy of REBOA is still debated. We aimed to conduct a systematic review assessing the clinical efficacy and safety of REBOA in patients with major trauma and uncontrolled haemorrhagic shock.MethodsWe systematically searched MEDLINE (PubMed), EMBASE and CENTRAL up to June 2020. All randomized controlled trials and observational studies that investigated the use of REBOA compared to resuscitative thoracotomy (RT) with/witho…

uncontrolled haemorrhagicmedicine.medical_specialtyRD1-811medicine.medical_treatmentReviewREBOAShock Hemorrhagiclaw.inventionInjury Severity Scorenursingsystematic reviewRandomized controlled trialQuality of lifelawmedicineHumansSystematic review Resuscitative Endovascular Balloon Occlusion of the Aorta Major trauma haemorrhage Resuscitative thoracotomyAdverse effectAortaResuscitative thoracotomybusiness.industryRC86-88.9Major traumaEndovascular ProceduresMedical emergencies. Critical care. Intensive care. First aidBalloon Occlusionmedicine.diseaseSettore MED/45 - Scienze Infermieristiche Generali Cliniche E Pediatrichemajor traumaAmputationMeta-analysisEmergency medicineEmergency MedicineObservational studySurgerybusinessWorld Journal of Emergency Surgery
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