Search results for "obstetric"

The diagnostic protocol of congenital uterine anomalies

2008

Exposure to natalizumab throughout pregnancy: effectiveness and safety in an Italian cohort of women with multiple sclerosis.

2022

ObjectiveAssessing the risk of clinical and radiological reactivation during pregnancy and post partum in women with multiple sclerosis (MS) treated with natalizumab (NTZ) throughout pregnancy (LONG_EXP) compared with women interrupting treatment before (NO_EXP) and within >−30 days and ≤90 days from conception (SHORT_EXP), and describing newborns’ outcomes.MethodsMaternal clinical and radiological outcomes and obstetric and fetal outcomes were retrospectively collected and compared among groups (NO_EXP, SHORT_EXP, LONG_EXP). Predictors of clinical and radiological reactivation were investigated through univariable and multivariable analysis.Results170 eligible pregnancies from 163 women…

Fertility-sparing approach in women affected by stage i and low-grade endometrial carcinoma: An updated overview

2021

Endometrial cancer (EC) is a deleterious condition which strongly affects a woman’s quality of life. Although aggressive interventions should be considered to treat high-grade EC, a conservative approach should be taken into consideration for women wishing to conceive. In this scenario, we present an overview about the EC fertility-sparing approach state of art. Type I EC at low stage is the only histological type which can be addressed with a fertility-sparing approach. Moreover, no myometrium and/or adnexal invasion should be seen, and lymph-vascular space should not be involved. Regarding the pharmaceutical target, progestins, in particular medroxyprogesterone acetate (MPA) or megestrol …

Impact of maternal age on infants' emotional regulation and psychomotor development

2021

AbstractBackgroundMaternal age has progressively increased in industrialized countries. Most studies focus on the consequences of delayed motherhood for women's physical and mental health, but little is known about potential effects on infants' neurodevelopment. This prospective study examines the association between maternal age and offspring neurodevelopment in terms of both psychomotor development (Ages & Stages Questionnaires-3) and emotional competences (Early Childhood Behavior Questionnaire).MethodsWe evaluated a cohort of healthy pregnant women aged 20–41 years and their offspring, assessed at 38 weeks gestation (n= 131) and 24 months after birth (n= 101). Potential age-related …

Disclosure of duplicative studies: damned if you don't

2012

Duplicative publication requires duplicative editorializing. There are many forms of lesser redundancy such as unacknowledged secondary analyses of randomized clinical trials, fragmentation of studies with concurrent submission to various journals, and serial updating of observational studies. These practices result in publication bias. We have revised our instructions to authors to include disclosure of similar articles that are published, in press, or submitted to other journals to the editors upon submission.

Sex differences in obstructive sleep apnoea.

2019

Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status,e.g.menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea–hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and…

Persistent tachypnea of infancy: Follow up at school age

2020

Background Persistent tachypnea of infancy (PTI) is a rare pediatric lung disease of unknown origin. The diagnosis can be made by clinical presentation and chest high resolution computed tomography after exclusion of other causes. Clinical courses beyond infancy have rarely been assessed. Methods Patients included in the Kids Lung Register diagnosed with PTI as infants and now older than 5 years were identified. Initial presentation, extrapulmonary comorbidities, spirometry and clinical outcome were analyzed. Results Thirty-five children older than 5 years with PTI diagnosed as infants were analyzed. At the age of 5 years, 74% of the patients were reported as asymptomatic and did not develo…

The respiratory gas values of the fetal and maternal blood in cartesian nomograms

1966

Respiratory gas values of maternal and fetal blood taken at delivery are represented in two Cartesian nomograms. They are based on data, published by vogel, fischer und thews (1965) and Fischer, Vogel und Thews (1965). The nomograms depict the interdependence of O2 pressure, O2 content, CO2 pressure and CO2 content, established by the O2 and CO2 dissociation curves, as well as by the Bohr effect and the Haldane effect. If two of the values are known, the remaining ones can be read from the nomograms.

Perinatal Database in Germany

1995

By collecting standardized data from up to 600,000 deliveries per year in Germany a nation-wide database has been established in recent years enabling not only regional and overregional quality control, but also the scientific analysis of rare maternal and fetal complication. During the observation period of 10 years the understanding of perinatal risk factors has considerably improved and the perinatal mortality has declined from 9.4 to 6.4 (per 1,000 deliveries). From the huge amount of calculations typical results are presented.

Long term gynaecological cancer survivors in Cote d'Or: health-related quality of life, social and professional reinsertion

2018

IF 2,392 (2017); International audience