Search results for "obstetric"

The course of fatigue in patients with gynecologic and breast cancer

2013

Objective: The objective of this study is to examine the course of fatigue in female cancer patients during the first months after treatment. Methods: We examined a sample of 110 patients suffering from gynecological or breast cancer. Fatigue was assessed with two questionnaires, the Multidimensional Fatigue Inventory (MFI) and the fatigue scale of the quality of life questionnaire European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30). Participants were tested during their stay in the hospital (t1), two weeks after discharge (t2), and three months after discharge (t3). Results: Fatigue in the patients’ sample was markedly higher than the general population reference val…

OP09.10: Hemodynamic effects of sildenafil administration in an animal model of preeclampsia

2011

Wavelet analysis and neural network classifiers to detect mid-sagittal sections for nuchal translucency measurement

2016

We propose a methodology to support the physician in the automatic identification of mid-sagittal sections of the fetus in ultrasound videos acquired during the first trimester of pregnancy. A good mid-sagittal section is a key requirement to make the correct measurement of nuchal translucency which is one of the main marker for screening of chromosomal defects such as trisomy 13, 18 and 21. NT measurement is beyond the scope of this article. The proposed methodology is mainly based on wavelet analysis and neural network classifiers to detect the jawbone and on radial symmetry analysis to detect the choroid plexus. Those steps allow to identify the frames which represent correct mid-sagitta…

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells

2010

Historically, our understanding of molecular genetic aspects of human germ cell development has been limited, at least in part due to inaccessibility of early stages of human development to experimentation. However, the derivation of pluripotent stem cells may provide the necessary human genetic system to study germ cell development. In this study, we compared the potential of human induced pluripotent stem cells (iPSCs), derived from adult and fetal somatic cells to form primordial and meiotic germ cells, relative to human embryonic stem cells. We found that ∼5% of human iPSCs differentiated to primordial germ cells (PGCs) following induction with bone morphogenetic proteins. Furthermore, …

On the use and abuse of register studies: The case of menopausal hormone therapy

2019

Bleeding symptoms at disease presentation and prediction of ensuing bleeding in inherited FVII deficiency.

2012

SummaryIndividuals with inherited factor VII (FVII) deficiency display bleeding phenotypes ranging from mild to severe, with 30% of patients having always been asymptomatic (non-bleeding). In 626 FVII-deficient individuals, by analysing data from the International Factor VII (IF7) Registry and the Seven Treatment Evaluation Registry (STER), we determined whether bleeding type at disease presentation and FVII coagulant activity (FVIIc) predict ensuing bleeds. At disease presentation/diagnosis, 272 (43.5%) individuals were non-bleeding, 277 (44.2%) had minor bleeds, and 77 (12.3%) had major bleeds. During a median nine-year index period (IP) observation, 87.9% of non-bleeding individuals at p…

Spousal support for personal goals and relationship satisfaction among women during the transition to parenthood

2010

The aim of this three-wave cross-lagged longitudinal study was to examine the prospective relationships between women’s goal-related spousal support and their relationship satisfaction during the transition to parenthood. Two-hundred and forty-six Finnish women who were either married or cohabited (45% primiparous; 55% multiparous) filled in questionnaires on personal projects (Little, 1983) and related spousal support, relationship satisfaction (Spanier, 1976), and background data three times: in their early pregnancy; one month before childbirth; and three months after childbirth. Among the primiparous women the results showed a cumulative cycle of goal-related spousal support and relati…

Intrauterine device migration into the bladder with stone formation after radiochemotherapy for cervical cancer: a case report

2020

Intrauterine contraceptive device (IUD) is one of the most frequently used contraceptive methods in the world. It is considered a safe and effective method of contraception. However, uterine perfor...

[Current developments and perspectives on the diagnosis and treatment of urinary incontinence and genital prolapse in women].

2012

As a key area of gynaecology, urogynaecology has undergone impressive changes in the past few years. Together with the high prevalence of functional pelvic floor disorders, modern anaesthesia procedures and the introduction of new, innovative minimally invasive operation techniques have led to a dramatic increase in the number of operations for incontinence and prolapses. The increasingly subtle diagnostic options, such as, e. g., 2D and 3D sonography of the pelvic floor provide unambiguous findings and facilitate decision making. Tension-free vaginal slings in retro-pubic, trans-obturator or single-incision techniques show a high success rate with few complications and have almost complete…

It Is Premature to Use Postmortem Sperm for Reproductive Purposes: a Data-Driven Opinion

2022

AbstractPostmortem sperm retrieval for reproductive purposes is an assisted reproduction procedure that offers women an opportunity to have a child using sperm retrieved from their deceased partners. The ethical issues of this procedure have been discussed in previous works. However, an assessment of the procedure using a scientific perspective is still lacking. Here, we aim to ascertain, using a biological standpoint, whether postmortem sperm should be rescued for reproductive purposes. Data suggest that it is premature to use postmortem sperm for reproductive purposes. This procedure should not be clinically applied until appropriate and comprehensive analyses have been completed. Such an…