Search results for "obstructive sleep apnea."

showing 10 items of 152 documents

Position paper on the management of patients with obstructive sleep apnea and hypertension: joint recommendations by the European Society of Hyperten…

2012

This article is aimed at addressing the current state of the art in epidemiology, pathophysiology, diagnostic procedures and treatment options for appropriate management of obstructive sleep apnea (OSA) in cardiovascular (particularly hypertensive) patients, as well as for the management of cardiovascular diseases (particularly arterial hypertension) in OSA patients. The present document is the result of the work done by a panel of experts participating in the European Union COST (COoperation in Scientific and Technological research) ACTION B26 on OSA, with the endorsement of the European Respiratory Society (ERS) and the European Society of Hypertension (ESH). These recommendations are par…

Societies Scientificmedicine.medical_specialtyPhysiologyArterial hypertension continuous positive airway pressure treatment guidelines hypertension treatment obstructive sleep apnoeaComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioCheyne–Stokes respirationEpidemiologyarterial hypertension continuous positive airway pressure treatment guidelines hypertension treatment obstructive sleep apneaInternal MedicinemedicineHumansmedia_common.cataloged_instanceEuropean unionIntensive care medicinemedia_commonSleep Apnea Obstructivebusiness.industrySleep apneaMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareComorbidityEuropeSurvival RateObstructive sleep apneaBlood pressureHypertensionPractice Guidelines as TopicPosition papermedicine.symptomCardiology and Cardiovascular Medicinebusiness
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Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea.

2012

Background: Intermittent hypoxia and obesity which are two pathological conditions commonly found in patients with obstructive sleep apnea (OSA), potentially enhance cancer progression. Objective: To investigate whether obesity and/or intermittent hypoxia (IH) mimicking OSA affect tumor growth. Methods: A subcutaneous melanoma was induced in 40 mice [22 obese (40–45 g) and 18 lean (20–25 g)] by injecting 106 B16F10 cells in the flank. Nineteen mice (10 obese/9 lean) were subjected to IH (6 h/day for 17 days). A group of 21 mice (12 obese/9 lean) were kept under normoxia. At day 17, tumors were excised, weighed and processed to quantify necrosis and endothelial expression of vascular endothe…

Vascular Endothelial Growth Factor Amedicine.medical_specialtyNecrosisMice ObeseSettore MED/10 - Malattie Dell'Apparato Respiratoriochemistry.chemical_compoundMiceSleep Apnea SyndromesInternal medicineMedicineAnimalsAnimal modelTumor growthObesityHypoxiaMelanomaCancerIntermittent hypoxiabusiness.industryMelanomaSleep apneaSleep apneaCancerIntermittent hypoxiaGeneral Medicinemedicine.diseaseObesityObstructive sleep apneaVascular endothelial growth factorMice Inbred C57BLDisease Models AnimalEndocrinologychemistrymedicine.symptombusinessNeoplasm TransplantationSleep medicine
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<p>Memory performances and personality traits in mothers of children with obstructive sleep apnea syndrome</p>

2019

Background Chronic diseases in pediatric age have been identified as stressful risk factors for parents. Studies on caregivers have documented the impact of chronic parenting stress on emotion and cognition. Aim To investigate the differences between a group of mothers of children affected by obstructive sleep apnea syndrome (OSAS) for at least 4 years and a group of mothers of typically developing children (TDC) in relation to parental stress, self-esteem, locus of control, and memory performances. Methods A group of 86 mothers (mean age 35.6±4.9, ranged between 32 and 41 years) of children with OSAS diagnosis, and a group of 52 mothers of TDC (mean age 35.9±4.2, ranged between 32 and 41 y…

business.industry05 social sciencesRespiratory diseaseCognitionmedicine.disease050105 experimental psychologyStress levelObstructive sleep apnea03 medical and health sciencesPsychiatry and Mental health0302 clinical medicineLocus of controlStress (linguistics)medicine0501 psychology and cognitive sciences030212 general & internal medicineStress conditionsBig Five personality traitsbusinessGeneral PsychologyClinical psychologyPsychology Research and Behavior Management
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Obstructive sleep apnea: arterial oxygen desaturation coincides with increases in systemic oxidative stress markers measured with continuous monitori…

2007

business.industryContinuous monitoringArterial oxygenSleep apneaGlutathionemedicine.diseaseMalondialdehydemedicine.disease_causeBiochemistryObstructive sleep apneachemistry.chemical_compoundchemistryPhysiology (medical)AnesthesiamedicinebusinessOxidative stressFree Radical Biology and Medicine
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Effect of rapid maxillary expansion on sleep apnea-hypopnea syndrome in growing patients. A meta-analysis.

2019

Background Changes produced in the upper airway after rapid maxillary expansion makes this procedure a therapeutic option for treating sleep apnea-hypopnea syndrome (SAHS) in children. The objective of this systematic review and meta-analysis was to analyze the evidence available for the effects of rapid maxillary expansion (RME) on SAHS, analyzing changes produced in oximetric variables: apnea-hypopnea index (AHI); oxygen saturation (SO2); sleep efficiency (SE), total sleep time (TST), percentage of rapid eye movement (REM) phase; and arousal index (AI). Material and Methods An electronic search was conducted in the PubMed, Scopus, Embase, and Cochrane databases, and in grey literature (Op…

business.industrySleep Apnea Hypopnea SyndromeSleep apneaOrthodonticsReview030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseObstructive sleep apnea03 medical and health sciences0302 clinical medicineSample size determinationMeta-analysisAnesthesiaUNESCO::CIENCIAS MÉDICASMedicineRapid maxillary expansionAirwaybusinessGeneral Dentistry030217 neurology & neurosurgeryOxygen saturation (medicine)Journal of clinical and experimental dentistry
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Signal processing procedures for the evaluation of the cardiovascular effects in the obstructive sleep apnea syndrome

2002

A new index, the cross-power index (CPI), is proposed to quantify the severity of obstructive sleep apnea syndrome (OSAS) in terms of its cardiovascular effects. On the basis of the influences that recurring drops in oxygen saturation have on systolic blood pressure variability of OSAS patients, CPI is defined as the integral of the cross-spectrum modulus between systolic blood pressure and oxygen saturation. In a test group of 22 subjects, CPI correctly identified all 15 OSAS patients included in the pool. Moreover, evaluation of CPI in six OSAS patients sleeping with and without a CPAP (continuous positive airway pressure) device demonstrated that CPAP treatment substantially reduced the …

business.industryTest groupmedicine.medical_treatmentHemodynamicsSettore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaBlood pressureAnesthesiaMedicineCpap treatmentPatient treatmentContinuous positive airway pressurebusinessCardiology and Cardiovascular MedicineSoftwareOxygen saturation (medicine)
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Effectiveness of mandibular advancement appliances in treating obstructive sleep apnea syndrome: A systematic review

2015

Objectives/Hypothesis Mandibular advancement devices are an alternative to continuous positive airway pressure for patients with mild or moderate obstructive sleep apnea/hypopnea syndrome (OSAHS). The main aim of this review was to assess the effectiveness of different devices in treating OSAHS, based on polysomnographic measurements such as the apnea/hypopnea index (AHI) and oxygen saturation, and on changes in the upper airway and improvements in the most common symptoms: snoring and somnolence. Their adverse effects were also noted. Study Design Systematic review. Methods Following an exhaustive search in the Medline, Scopus, and Cochrane Library databases, 22 articles published in the p…

business.industrymedicine.medical_treatmentDentistryApneaExcessive daytime sleepiness030206 dentistryCochrane Librarymedicine.diseaserespiratory tract diseasesObstructive sleep apnea03 medical and health sciences0302 clinical medicinestomatognathic systemOtorhinolaryngologymedicineContinuous positive airway pressuremedicine.symptomAirwaybusinessHypopnea030217 neurology & neurosurgerySomnolenceThe Laryngoscope
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Measurement of Pharyngeal Pressure in Patients using Nasal CPAP

1995

In patients with obstructive sleep apnea syndrome (OSAS), nasal continuous positive airway pressure (nCPAP) prevents pharyngeal collapse by applying positive pressure transnasally. Currently there are not objective criteria to determine whether surgical improvement of nasal resistance is necessary in patients undergoing nCPAP treatment. In 16 patients with documented OSAS, inspiratory and expiratory pressures in the pharynx were measured during nCPAP with pressures ranging from 5 to 20 mbar. Identical studies were performed in 12 patients with severe nasal obstruction without OSAS and in eight normal patients. The results of each group were compared to the nasal resistance as measured by a…

business.industrymedicine.medical_treatmentPharynxPositive pressurerespiratory systemmedicine.diseaseObstructive sleep apneaPharyngeal muscles03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureAcoustic rhinometryOtorhinolaryngology030220 oncology & carcinogenesisAnesthesiaotorhinolaryngologic diseasesMedicineIn patientContinuous positive airway pressure030223 otorhinolaryngologybusinessNoseAmerican Journal of Rhinology
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Long-term positive airway pressure therapy is associated with reduced total cholesterol levels in patients with obstructive sleep apnea : data from t…

2020

Background and aim: Obstructive sleep apnea (OSA) is an independent risk factor for dyslipidemia. The current study examined the effects of positive airway pressure (PAP) treatment on lipid status in the European Sleep Apnea Database (ESADA). Methods: The prospective cohort study enrolled 1564 OSA subjects (74% male, mean age 54 ± 11y, body mass index (BMI) 32.7 ± 6.6 kg/m2 and apnea-hypopnea index (AHI) 40.3 ± 24.4 n/h) undergoing PAP therapy for at least three months (mean 377.6 ± 419.5 days). Baseline and follow-up total cholesterol (TC) from nine centers were analyzed. Repeated measures and logistic regression tests (adjusted for age, sex, weight changes, lipid lowering medication, PAP …

cardiovascular riskAdultMalemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato RespiratorioPositive airway pressure03 medical and health sciences0302 clinical medicineInternal medicinePositive airway pressuremedicineCardiovascular risk Cholesterol Hypoxia Sleep apneaHumanspositive airway pressureProspective StudiesRisk factorProspective cohort studyHypoxiaAgedSleep Apnea ObstructiveFramingham Risk ScoreContinuous Positive Airway Pressurebusiness.industryhypoxiaSleep apneaSleep apneacholesterolGeneral MedicineMiddle Agedmedicine.diseasesleep apneaCardiovascular riskObstructive sleep apneaCardiovascular risk ; Cholesterol ; Hypoxia ; Positive airway pressure ; Sleep apnea.Cholesterol030228 respiratory systemPatient ComplianceFemaleHuman medicinebusinessBody mass index030217 neurology & neurosurgeryDyslipidemiaSleep medicine
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Cluster Analysis of Home Polygraphic Recordings in Symptomatic Habitually-Snoring Children: A Precision Medicine Perspective

2022

(1) Background: Sleep-disordered breathing (SDB) is a frequent problem in children. Cluster analyses offer the possibility of identifying homogeneous groups within a large clinical database. The application of cluster analysis to anthropometric and polysomnographic measures in snoring children would enable the detection of distinctive clinically-relevant phenotypes; (2) Methods: We retrospectively collected the results of nocturnal home-based cardiorespiratory polygraphic recordings and anthropometric measurements in 326 habitually-snoring otherwise healthy children. K-medoids clustering was applied to standardized respiratory and anthropometric measures, followed by Silhouette-based statis…

children; cluster analysis; obstructive sleep apnea; polygraphy; sleep apnea; sleep-disordered breathing; snoringpolygraphychildrensleep-disordered breathingGeneral Medicinesleep apneaobstructive sleep apneasnoringcluster analysisJournal of Clinical Medicine
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