Search results for "ocal"

showing 10 items of 5464 documents

Surgical sphincter saving approach and topical nifedipine for chronic anal fissure with hypertonic internal anal sphincter

2020

PURPOSE The role of augmented internal anal sphincter (IAS) tone in the genesis of posterior chronic anal fissure (CAPF) is still unknown. Lateral internal sphincterotomy is the most employed surgical procedure, nevertheless it is burdened by high risk post-operative anal incontinence. The aim of our study is to evaluate results of sphincter saving procedure with post-operative pharmacological sphincterotomy for patients affected by CAPF with IAS hypertonia. Methods: We enrolled 30 patients, undergone fissurectomy and anoplasty with V-Y cutaneous flap advancement; all patients received topical administration of nifedipine 0.3% and lidocaine 1.5% ointment-based therapy before and for 15 days…

medicine.medical_specialtyLidocaineNifedipinemedicine.medical_treatmentAdministration TopicalAnal CanalSurgical FlapsInternal anal sphincterFissurectomyOintmentsMuscle HypertoniaNifedipineMuscle HypertoniamedicineHumansProspective StudiesAnesthetics LocalAnestheticsAnal fissureAnal fissure Anoplasty Fissurectomy Lidocaine Nifedipine Proctology Administration Topical Anal Canal Anesthetics Local Calcium Channel Blockers Chronic Disease Combined Modality Therapy Humans Lidocaine Muscle Hypertonia Ointments Prospective Studies Surgical Flaps Treatment Outcome Fissure in Ano Nifedipinebusiness.industryLidocaineAnal canalAnoplastymedicine.diseaseCalcium Channel BlockersCombined Modality TherapySurgerymedicine.anatomical_structureTreatment OutcomeTopicalLocalAdministrationChronic DiseaseHypertoniaSurgeryFissure in Anomedicine.symptomAnal fissureProctologyLateral internal sphincterotomybusinessmedicine.drug
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Comparison of anesthetic efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine for inferior alveolar nerve b…

2014

Objectives: This study was done to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine with that of 2% lidocaine with 1:80,000 epinephrine during pulpectomy in patients with irreversible pulpitis for inferior alveolar nerve block in mandibular posterior teeth. Material and Methods: Patients with irreversible pulpitis referred to the Department of Conservative Dentistry and Endodontics, K.D. Dental College, randomly received a conventional inferior alveolar nerve block containing 1.8 mL of either 4% articaine with 1:100,000 epinephrine or 2% lidocaine with 1:80,000 epinephrine. After the patient's subjective assessment of lip anesthesia, the absence/presence of pulpal …

medicine.medical_specialtyLidocainebusiness.industryLocal anestheticmedicine.drug_classResearchDentistryOdontologíaInferior alveolar nervemedicine.diseaseEndodonticsArticaine:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOperative Dentistry and EndodonticsEpinephrinestomatognathic systemAnesthesiaAnestheticUNESCO::CIENCIAS MÉDICASmedicinePulpitisbusinessGeneral Dentistrymedicine.drug
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Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

2017

A patient's willingness to cooperate is an absolute precondition for successful awake intubation of the trachea. Whilst drug-sedation of patients can jeopardize their spontaneous breathing, topical anesthesia of the airway is a popular technique. The spray-as-you-go technique represents one of the simplest opportunities to anesthetize the airway mucosa. The application of local anesthetic through the working channel of the flexible endoscope is a widespread practice for anesthetists as well as pulmonologists. There is neither need for additional devices nor special training as a pre-requisite to perform this technique. However, a known clinical problem is the coughing and gagging reflex tha…

medicine.medical_specialtyLidocainemedicine.drug_classmedicine.medical_treatmentGeneral Chemical Engineering030204 cardiovascular system & hematologyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicinePharyngeal reflexAnesthesiologymedicineIntubation IntratrachealIntubationHumansAnesthetics LocalGeneral Immunology and MicrobiologyLocal anestheticbusiness.industryGeneral NeuroscienceLidocaineEndoscopySurgeryOxygen030220 oncology & carcinogenesisAnesthesiaAnestheticBreathingMedicinebusinessAirwaymedicine.drugAnesthesia Local
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Endorektale Sonographie zur präoperativen Beurteilung der Infiltrationstiefe von Rektumtumoren

1990

From June 1987 to February 1990, 142 out of 319 patients with rectal tumours were investigated by ultrasound scanning with the object of ascertaining the depth to which the tumour had infiltrated. This examination proved completely feasible in 130 of these patients (84 men, 46 women, mean age 61.7 [42-84] years). Postoperative histological examination revealed an adenoma (n = 59) or a T1 carcinoma (n = 19), while intrarectal ultrasonography disclosed the same findings in 79 patients (true-positive in 75 cases). A T2-tumour was diagnosed by histological examination in 24 patients, and by ultrasonography in 22 (true-positive in 18 cases). The histological diagnosis of a tumour in stage T3 or …

medicine.medical_specialtyLocal excisionAdenomabusiness.industryUltrasoundGeneral MedicineRectal Tumorsmedicine.diseaseCarcinomaMedicineRadiologyStage (cooking)UltrasonographybusinessInfiltration (medical)DMW - Deutsche Medizinische Wochenschrift
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Die transanale endoskopische mikrochirurgische Behandlung von „low risk“ und „high risk“ Karzinomen der Rektumschleimhaut

1993

Transanal endoscopic microsurgery was performed in 78 patients with rectal carcinoma. Complications were observed in two patients (2.5%), no patient died after local excision. In case of local excised “low risk” T1-carcinoma and tumor free margins no recurrences were observed.

medicine.medical_specialtyLocal excisionbusiness.industrymedicine.medical_treatmentRectal carcinomamedicineMicrosurgerybusinessTumor-Free MarginsSurgery
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Treatment patterns in older patients with locally advanced head and neck squamous cell carcinoma

2021

OBJECTIVES: We aimed to assess patterns of care delivered to older patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC), and to analyze the use of geriatric assessment (GA) and assessment of quality of life (QoL).MATERIALS AND METHODS: Members of the head and neck cancer group and the older task force of the European Organisation for Research and Treatment of Cancer (EORTC), members the European Head and Neck Society and members of national groups in Europe were asked to complete a questionnaire about treatment delivered, use of GA, and QoL assessment in older patients with LA-HNSCC.RESULTS: Investigators from 111 centers replied, including 90 (81.1%) academic cen…

medicine.medical_specialtyLocally advancedMEDLINE03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesmedicineHumans030212 general & internal medicineProspective cohort studyAgedbusiness.industrySquamous Cell Carcinoma of Head and NeckHead and neck cancerCancermedicine.diseaseHead and neck squamous-cell carcinomaCANCERhumanitiesOncologyOropharyngeal CarcinomaHead and Neck Neoplasms030220 oncology & carcinogenesisPhysical therapyCarcinoma Squamous CellQuality of LifeGeriatrics and GerontologybusinessJournal of Geriatric Oncology
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Trend of hospitalized cases of oral cancer in Brazil and its relationship with oral health coverage in public health system between 2009 and 2017

2020

Background This study aimed to analyze the trend in the number of hospitalized cases of oral cancer in Brazil, according to the coverage of oral health services in public health system, and also investigate the influence of healthcare and clinical characteristics on the severity of oral cancer cases. Material and Methods This retrospective study considered the period between 2009 and 2017. Data from the Hospital Registry of Cancer from the National Cancer Institute were used, considering the primary locations C00 to C06. Detailed information including sex, age, alcohol and tobacco use, year of first consultation, and the clinical stage of the cases were also collected. The frequency of hosp…

medicine.medical_specialtyMEDLINEOral HealthDental SpecialtyOral healthLogistic regressionhistologic differentiation03 medical and health sciences0302 clinical medicineHealth caremedicineHumansGeneral DentistryUNESCO:CIENCIAS MÉDICASRetrospective StudiesOral Medicine and Pathologyoral squamous cell carcinoma (oscc)locally advanced diseasebusiness.industryResearchPublic healthCancerRetrospective cohort study030206 dentistrymedicine.diseaseOtorhinolaryngologyFamily medicinecervical lymph node metastasisMouth NeoplasmsSurgeryPublic HealthbusinessBrazilMedicina Oral Patología Oral y Cirugia Bucal
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Surface Topographies of Glaucoma Drainage Devices and Their Influence on Human Tenon Fibroblast Adhesion

2010

PURPOSE. This study was performed to investigate the surface topography of different glaucoma drainage devices and to determine the effects of surface roughness on cell adhesion of cultured human tenon fibroblasts.METHODS. The surface topography of four widely used devices (Ahmed FP7 and Ahmed S-2; New World Medical, Inc., Rancho Cucamonga, CA; Baerveldt BG101-350; Advanced Medical Optics, Irvine, CA; and Molteno S1; Molteno Ophthalmic Ltd., Dunedin, New Zealand) was investigated by scanning electron microscopy, and roughness was quantified by white-light confocal microscopy. Cells were grown for 72 hours on the surfaces of implants affixed to standard culture dishes. The cells were labeled…

medicine.medical_specialtyMaterials scienceScanning electron microscopeConfocalSurface finishProsthesis Designlaw.inventionConfocal microscopylawBone plateMicroscopyCell AdhesionSurface roughnessmedicineHumansFasciaGlaucoma Drainage ImplantsCell adhesionCells CulturedMicroscopy ConfocalFibroblastsSurgeryMicroscopy Electron ScanningCell DivisionProtein BindingBiomedical engineeringInvestigative Opthalmology & Visual Science
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Endoscopic detection of early lower gastrointestinal cancer

2005

The prognosis for patients with malignancies of the lower gastrointestinal tract is strictly dependent on early detection of premalignant and malignant lesions. What should an ideal screening and surveillance colonoscopy be able to accomplish? The technique should allow detection of large but also discrete mucosal alterations. Ideally, endoscopic discrimination between neoplastic and non-neoplastic lesions would be possible during the ongoing procedure. At present, endoscopy can be performed with powerful new endoscopes. Comparable to the rapid development in chip technology, the optical features of the newly designed endoscopes offer resolutions, which allow new surface details to be seen.…

medicine.medical_specialtyMicroscopy ConfocalNarrow-band imagingLower Gastrointestinal TractStaining and Labelingmedicine.diagnostic_testColorectal cancerbusiness.industryGastroenterologyColonoscopyLower Gastrointestinal TractColonoscopymedicine.diseaseChromoendoscopyEndoscopyEarly DiagnosismedicineEndomicroscopyHumansColitis UlcerativeGastrointestinal cancerRadiologyColorectal NeoplasmsbusinessBest Practice & Research Clinical Gastroenterology
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Non‐invasive diagnostic techniques in pigmentary skin disorders and skin cancer

2021

Background Diagnosis of pigmentary skin disorders, pre-cancerous and cancerous skin diseases is traditionally relied on visual assessment. The most widely applied invasive diagnostic technique is the skin biopsy. There have been significant technological advances in non-invasive diagnostic methods for skin disorders. Objective The objective of this article is to discuss different non-invasive diagnostic modalities, used in the diagnosis of pigmentary skin disorders and cutaneous cancers. Methods Comprehensive literature search was performed to screen articles related to non-invasive diagnostic techniques in pigmentary skin disorders and cutaneous cancers. Articles published in journals inde…

medicine.medical_specialtyMicroscopy ConfocalSkin Neoplasmsmedicine.diagnostic_testbusiness.industryNon invasiveMagnetic resonance imagingDermatologymedicine.diseaseSensitivity and SpecificityDermatologyDiagnostic modalitiesClinical trialOptical coherence tomographyBiopsySkin biopsymedicineHumansSkin cancerbusinessSkinUltrasonographyJournal of Cosmetic Dermatology
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