Search results for "ocular"

showing 10 items of 1219 documents

Sensibilidad al contraste tras cirugía de cristalino transparente con lente intraocular multifocal asférica difractiva

2013

PURPOSE: To evaluate distance and near contrast sensitivity (CS) under photopic and mesopic conditions before and after refractive lens exchange (RLE) and implantation of the aspheric AcrySof®ReSTOR® (SN6AD3 model) intraocular lens (IOL). METHODS:Seventy-four eyes of 37 patients after RLE underwent bilateral implantation with the aspheric AcrySof ReSTOR IOL. The patient sample was divided into myopic and hyperopic groups. Monocular uncorrected visual acuity at distance and near (UCVA and UCNVA, respectively) and monocular best corrected visual acuity at distance and near (BCVA and BCNVA, respectively) were measured before and 6 months postoperatively. Monocular CS function was measured at t…

HiperopiaHyperopiaPhacoemulsificationVisual acuityMiopíaLens implantation intraocularImplantación de lentes intraocularesMyopiaAgudeza visualLens cristallineCristalinoFacoemulsificación
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The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance

2005

During the last few years, the endocannabinoid system has emerged as a highly relevant topic in the scientific community. Many different regulatory actions have been attributed to endocannabinoids, and their involvement in several pathophysiological conditions is under intense scrutiny. Cannabinoid receptors, named CB1 receptor and CB2 receptor, first discovered as the molecular targets of the psychotropic component of the plant Cannabis sativa, participate in the physiological modulation of many central and peripheral functions. CB2 receptor is mainly expressed in immune cells, whereas CB1 receptor is the most abundant G protein-coupled receptor expressed in the brain. CB1 receptor is expr…

Hypothalamo-Hypophyseal Systemmedicine.medical_specialtyCannabinoid receptorEndocrinology Diabetes and Metabolismmedicine.medical_treatmentmedia_common.quotation_subjectPituitary-Adrenal SystemEndocrine SystemBiologyEndocrinologyInternal medicineCannabinoid Receptor ModulatorsmedicineCannabinoid receptor type 2ACID AMIDE HYDROLASEAnimalsHumansEndocrine systemMESSENGER-RNA EXPRESSIONVAGAL AFFERENT NEURONSObesityReceptors CannabinoidReceptorCannabinoid Receptor Antagonistsmedia_commonmusculoskeletal neural and ocular physiologyACTIVATED PROTEIN-KINASECENTRAL-NERVOUS-SYSTEMDISTINCT NEURONAL SUBPOPULATIONSAppetiteEndocannabinoid systemCANNABINOID CB1 RECEPTORCORTICOTROPIN-RELEASING-FACTOREndocrinologynervous systemCannabinoid receptor antagonistlipids (amino acids peptides and proteins)PITUITARY-ADRENAL AXISPREIMPLANTATION MOUSE EMBRYOCannabinoidEnergy MetabolismNeurosciencepsychological phenomena and processesEndocannabinoidsEndocrine Reviews
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Tratamiento de las ectasias corneales asociadas a LASIK con anillos intraestromales

2022

INTRODUCCIÓN: La ectasia corneal es una de sus complicaciones más graves de la cirugía LASIK. Está asociada a un adelgazamiento y un progresivo incurvamiento corneal y los anillos intracorneales (ICRS) se han propuesto como opción terapéutica debido a que inducen un aplanamiento. OBJETIVO: Evaluar los cambios producidos por los ICRS en pacientes diagnosticados de ectasias secundarias a LASIK. MATERIAL Y MÉTODOS: Es un estudio retrospectivo donde se incluyeron 26 ojos con ectasia post-LASIK los cuales fueron tratados con ICRS tipo Ferrara (AJL, Vitoria). Se les realizó un examen refractivo (agudeza visual (AV) y la refracción subjetiva). Mediante Pentacam®HR (Oculus: OtikgerateGmbH, Wetzlar,…

ICRS:CIENCIAS MÉDICAS ::Cirugía ::Cirugía ocular [UNESCO]:CIENCIAS MÉDICAS ::Ciencias clínicas::Oftalmología [UNESCO]anillos intraestromalesectasias secundarias a LASIKUNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::OftalmologíaLASIKUNESCO::CIENCIAS MÉDICAS ::Cirugía ::Cirugía ocularectasia corneal
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Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)

2020

According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored al…

ISAR International Severe Asthma RegistrySHARPPediatricsSevere asthmaSA severe asthmaBiologics Oral corticosteroids Real-life Registr Severe asthmaOmalizumabforced expiratory volume in the 1st secondFood &ampGrading of Recommendations Assessmentchronic rhinosinusitis with nasal polyposisFEV1chemistry.chemical_compound0302 clinical medicineQuality of lifeEMAReal WorldEuropean Medicines AgencyBiologics; Oral corticosteroids; Real-life; Registr; Severe asthmaOral corticosteroidsFDA Food & Drug AdministrationImmunology and Allergy030223 otorhinolaryngologySevere Heterogeneous Asthma Research collaborationmusculoskeletal neural and ocular physiologyReal-lifeCRSwNPOCSsBenralizumabDupilumabCRSwNP chronic rhinosinusitis with nasal polyposisGRADESHARP Severe Heterogeneous Asthma Research collaboration Patient-centredSevere Asthma Network in ItalyFDAmedicine.drugPulmonary and Respiratory Medicinelcsh:Immunologic diseases. Allergymedicine.medical_specialtyDrug AdministrationGINA Global Initiative for AsthmaRW Real WorldImmunologymacromolecular substancesRWSettore MED/10 - Malattie Dell'Apparato RespiratorioBiologicsInternational Severe Asthma RegistryISAR03 medical and health sciencesSADisease registrySARP Severe Asthma Research ProgramPatient-centredmedicineAsthmabusiness.industrySettore MED/09 - MEDICINA INTERNASANI Severe Asthma Network in ItalySANIBiological productmedicine.diseaseOCSs Oral CorticoSteroidsGINASARPSevere Asthma Research ProgramFEV1 forced expiratory volume in the 1st second030228 respiratory systemchemistrynervous systemRegistrEMA European Medicines AgencyDevelopment and EvaluationSevere asthma Biologics Oral corticosteroids Real-life Registrbusinesslcsh:RC581-607Global Initiative for AsthmaMepolizumabGRADE Grading of Recommendations Assessment Development and Evaluation
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Noninfectious uveitis: strategies to optimize treatment compliance and adherence.

2015

Noninfectious uveitis includes a heterogenous group of sight-threatening ocular and systemic disorders. Significant progress has been made in the treatment of noninfectious uveitis in recent years, particularly with regard to the effective use of corticosteroids and non-corticosteroid immunosuppressive drugs, including biologic agents. All of these therapeutic approaches are limited, however, by any given patient's ability to comply with and adhere to their prescribed treatment. In fact, compliance and adherence are among the most important patient-related determinants of treatment success. We discuss strategies to optimize compliance and adherence.

Immunosuppressive treatmentmedicine.medical_specialtynoninfectious uveitisbusiness.industryintraocular inflammationimmunosuppressive treatmentReviewcomplianceBiologic AgentsIntraocular inflammationOphthalmologyInfectious uveitisTreatment successTreatment complianceOphthalmologymedicinetherapeutic failureTherapeutic failureadherenceIntensive care medicinebusinessClinical ophthalmology (Auckland, N.Z.)
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"Table 12" of "Measurement of event shape and inclusive distributions at s**(1/2) = 130-GeV and 136-GeV."

1997

Thrust Major distribution. Axis definition is from corrected charged plus neutral particles.

Inclusive133.0genetic structuresmusculoskeletal neural and ocular physiologyE+ E- --> NEUTRAL XE+ E- ScatteringPhysics::Space PhysicsDN/DMAJORHigh Energy Physics::ExperimentE+ E- --> CHARGED XSingle Differential Distributionhuman activities
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Informe de la salud visual y ocular de los países que conforman la Red Epidemiológica Iberoamericana para la Salud Visual y Ocular (REISVO), 2009 y 2…

2015

A pesar de que se han hecho importantes progresos en el cuidado de la salud ocular, la prevalencia de la ceguera evitable sigue siendo inaceptablemente alta en muchos países y comunidades (OMS, 2009). La salud visual es un tema de la agenda política en algunos países; sin embargo, aún no se cuenta con un sistema de información que permita identificar la situación de morbilidad en salud visual en Iberoamérica, para poder priorizar y planificar la orientación de los servicios de atención en optometría y oftalmología. Para que existan planes de salud, deben establecerse líneas de base a través de un diagnóstico epidemiológico y de necesidades de la población; por esta razón, REISVO ha desarrol…

Infants discapacitats sensorialsSalud OcularSalut pública Cooperació internacionalCiencias MédicasUlls Malalties i defectesSalud visualGeneral Medicine
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Retinal Fundus Multi-Disease Image Dataset (RFMiD): A Dataset for Multi-Disease Detection Research

2021

The world faces difficulties in terms of eye care, including treatment, quality of prevention, vision rehabilitation services, and scarcity of trained eye care experts. Early detection and diagnosis of ocular pathologies would enable forestall of visual impairment. One challenge that limits the adoption of computer-aided diagnosis tool by ophthalmologists is the number of sight-threatening rare pathologies, such as central retinal artery occlusion or anterior ischemic optic neuropathy, and others are usually ignored. In the past two decades, many publicly available datasets of color fundus images have been collected with a primary focus on diabetic retinopathy, glaucoma, age-related macular…

Information Systems and Managementgenetic structuresVisual impairmentGlaucomaDiseaseFundus (eye)030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinerare pathology detectionmedicineVision rehabilitationmulti-label classificationretinal fundus imagesbusiness.industryocular diseaseDiabetic retinopathyMacular degenerationmedicine.diseaselcsh:Zeye diseaseslcsh:Bibliography. Library science. Information resourcesComputer Science Applicationsclassification030221 ophthalmology & optometryOptometryCentral retinal artery occlusionsense organsmedicine.symptombusinessInformation SystemsData
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mGluR control of interneuron output regulates feedforward tonic GABAA inhibition in the visual thalamus

2011

Metabotropic glutamate receptors (mGluRs) play a crucial role in regulation of phasic inhibition within the visual thalamus. Here we demonstrate that mGluR-dependent modulation of interneuron GABA release results in dynamic changes in extrasynaptic GABAA receptor (eGABAAR)-dependent tonic inhibition in thalamocortical (TC) neurons of the rat dorsal lateral geniculate nucleus (dLGN). Application of the group I selective mGluR agonist dihydroxyphenylglycine produces a concentration-dependent enhancement of both IPSC frequency and tonic GABAA current (IGABAtonic) that is due to activation of both mGluR1a and mGluR5 subtypes. In contrast, group II/III mGluR activation decreases both IPSC freque…

InterneuronReceptors metabotropic glutamateAction PotentialsMetabotropic glutamate receptors GABA dorsal geniculate neurons ratNeurotransmissionReceptors Metabotropic GlutamateQ1DihydroxyphenylglycineSynaptic TransmissionSettore BIO/09 - Fisiologiagamma-Aminobutyric acidArticlechemistry.chemical_compoundThalamusKidney glomerulusInterneuronsmedicineAnimalsVisual Pathwaysgamma-Aminobutyric AcidChemistryGABAA receptorGeneral Neurosciencemusculoskeletal neural and ocular physiologyNeural InhibitionReceptors GABA-ARatsElectrophysiologymedicine.anatomical_structureInhibitory Postsynaptic Potentialsnervous systemMetabotropic glutamate receptorRC0321GABAergicNeuronNeurosciencemedicine.drug
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Visual and optical performance with hybrid multifocal intraocular lenses

2010

During the past years, the wish to become independent of spectacles has been growing among cataract and presbyopic patients due to many factors, such as the increase in near visual demands, the aesthetic need for a spectacle-free image and ageing of refractive surgery patients, among others. This review assesses recently published studies that analyse visual and optical performance through different metrics of eyes implanted with multifocal intraocular lenses (IOLs), particularly hybrid IOL designs. The published evidence suggests that hybrid multifocal IOLs provide very good outcomes in a number of visual and optical performance parameters. Patients implanted with this type of IOL obtain a…

Intraocular LensesOptical PerformanceVisual acuitygenetic structuresCompensation Comparisonmedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityMethodKeratomileusislaw.inventionGlareLensTratamiento médicoSensitivitylawRefractive surgeryMedicineContrast (vision)MonovisionPostoperative Periodmedia_commonVistaLenses IntraocularMultifocalsGlare (vision)Equipment DesignRefractive ErrorsLens (optics)Bilateral ImplantationApodized Diffractive IolOftalmologíamedicine.symptommedicine.medical_specialtyIn-Situ KeratomileusisRefractivemedia_common.quotation_subjectHigh-Order AberrationsContrast SensitivityOphthalmologyAberrometryClinical-OutcomesHumansRetinal StraylightDepth Perceptionbusiness.industryAberrometryMultifocal intraocular lensContrasteye diseasesOphthalmologyOptometrysense organsbusinessOptometry
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