Search results for "oksitosiini"
showing 4 items of 4 documents
Socio-Reproductive Conflicts and the Father’s Curse Dilemma
2018
Evolutionary conflicts between males and females can manifest over sexually antagonistic interactions at loci or over sexually antagonistic interests within a locus. The latter form of conflict, intralocus sexual conflict, arises from sexually antagonistic selection and constrains the fitness of individuals through a phenotypic compromise. These conflicts, and socio-reproductive interactions in general, are commonly mediated by hormones, and thus predictive insights can be gained from studying their mediating effects. Here, we integrate several lines of evidence to describe a novel, hormonally mediated reproductive dilemma that we call the father’s curse, which results from an intralocus co…
Being moved by listening to unfamiliar sad music induces reward‐related hormonal changes in empathic listeners
2021
Many people enjoy sad music, and the appeal for tragedy is widespread among the consumers of film and literature. The underlying mechanisms of such aesthetic experiences are not well understood. We tested whether pleasure induced by sad, unfamiliar instrumental music is explained with a homeostatic or a reward theory, each of which is associated with opposite patterns of changes in the key hormones. Sixty-two women listened to sad music (or nothing) while serum was collected for subsequent measurement of prolactin (PRL) and oxytocin (OT) and stress marker (cortisol and adrenocorticotropic hormone) concentrations. Two groups of participants were recruited on the basis of low and high trait e…
Intranasal oxytocin decreases fear generalization in males, but does not modulate discrimination threshold
2021
Background: A previously acquired fear response often spreads to perceptually or conceptually close stimuli or contexts. This process, known as fear generalization, facilitates the avoidance of danger, and dysregulations in this process play an important role in anxiety disorders. Oxytocin (OT) has been shown to modulate fear learning, yet effects on fear generalization remain unknown. Methods: We employed a randomized, placebo-controlled, double-blind, between-subject design during which healthy male participants received either intranasal OT or placebo (PLC) following fear acquisition and before fear generalization with concomitant acquisition of skin conductance responses (SCRs). Twenty-…
Epigenetic mechanisms behind phenotypic changes in different population densities in bank voles (Myodes glareolus)
2017
Metsämyyrän (Myodes glareolus) fenotyyppisten muutosten epigeneettiset mekanismit eri populaatiotiheyksissä. Epigeneettisilla mekanismeilla on perustava rooli normaalissa geeniekspression aktiivisuudessa ja ne voidaan nähdä molekulaaristen prosessien systeeminä, joka reagoi ympäristötekijöihin ja säätelee geenisäätelyä muuttamatta alkuperäistä DNA-sekvenssiä. DNA-metylaatio on eniten tutkittu epigeneettinen mekanismi jolla on tärkeä rooli geenien säätelyssä normaalin solujen kehityksen aikana. Metylaatio ilmenee tyypillisesti CpG-dinukleotideissa, joissa metyyliryhmä kiinnittyy 5’-sytosiiniin (C) jota seuraava emäs on guaniini (G). Tämä voi estää näihin CpG-paikkoihin liittyvien geenien ilm…