Search results for "older"

showing 10 items of 1264 documents

Municipal Integrated Coastal Management Facilitation in Latvia: Piloting Public Multi-Thematical Monitoring

2021

This paper contains a pilot study on coastal values and potential means of determining and characterising them in the terms of coastal planning and management. The research case study took place in the coastal region of North East Latvia – in the municipality of Salacgriva. The municipality coast is very diverse: coastal access, landscape and the whole biogeography is changing very much along the whole 54 km, being also rich in various natural and cultural heritage assets. Such great coastal variety in the limits of one administrative territory does require very selective governance approaches and dynamic management to be realized by local administration, which has very limited necessary ca…

Shoregeographygeography.geographical_feature_categorybusiness.industryCorporate governanceEnvironmental resource managementStakeholderDistribution (economics)Variety (cybernetics)Cultural heritageCitizen scienceGeneral Earth and Planetary SciencesbusinessCoastal managementGeneral Environmental ScienceRegional Formation and Development Studies
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Monoclonal gammopathy of ocular significance (MGOS) – a short survey of corneal manifestations and treatment outcomes

2021

Monoclonal gammopathy of ocular significance (MGOS) is a rare subset of monoclonal gammopathy of clinical significance occurring secondary to plasma cell disorders and causing ocular manifestations. We identified 23 patients with paraproteinemic keratopathy (PPK) in the setting of monoclonal gammopathy of unknown significance (MGUS, 10), smoldering multiple myeloma (SMM, 3) or multiple myeloma (MM, 10). Many of these patients with PPK (11/23) presented decreased vision. All patients with MM and 40% of those with other diagnoses such as SMM and MGUS received systemic therapy with or without autologous stem cell transplantation. Four eyes of four patients were treated by penetrating keratopla…

Smoldering Multiple MyelomaCancer Researchmedicine.medical_specialtyVisual acuitygenetic structuresMonoclonal gammopathy of clinical significancemonoclonal gammopathy of ocular significanceTreatment outcomeParaproteinemiasPlasma cellMonoclonal Gammopathy of Undetermined SignificanceTransplantation AutologousSystemic therapyGastroenterologyMonoclonal gammopathy of clinical significance; monoclonal gammopathy of ocular significance; multiple myeloma; paraproteinemic keratopathyCorneal DiseasesAutologous stem-cell transplantationhemic and lymphatic diseasesInternal medicinemedicineHumansClinical significanceMultiple myelomabusiness.industryHematopoietic Stem Cell TransplantationHematologymedicine.diseaseeye diseasesMonoclonal gammopathyparaproteinemic keratopathyTreatment Outcomemedicine.anatomical_structureOncologyNeoplasm Recurrence Localmedicine.symptomMultiple MyelomabusinessLeukemia & Lymphoma
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Circulating tumor and immune cells for minimally invasive risk stratification of smoldering multiple myeloma

2022

Abstract Purpose: Early intervention in smoldering multiple myeloma (SMM) requires optimal risk stratification to avoid under- and overtreatment. We hypothesized that replacing bone marrow (BM) plasma cells (PC) for circulating tumor cells (CTC), and adding immune biomarkers in peripheral blood (PB) for the identification of patients at risk of progression due to lost immune surveillance, could improve the International Myeloma Working Group 20/2/20 model. Experimental Design: We report the outcomes of 150 patients with SMM enrolled in the iMMunocell study, in which serial assessment of tumor and immune cells in PB was performed every 6 months for a period of 3 years since enrollment. Resul…

Smoldering Multiple MyelomaCancer ResearchmyelomaOncologyDisease ProgressionHumansImmunoglobulin Light ChainsPrognosisMultiple MyelomaRisk Assessmentcirculating tumor cellimmune profile.Clinical Cancer Research
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FlowCT for the analysis of large immunophenotypic data sets and biomarker discovery in cancer immunology

2022

Key Points FlowCT is a new computational workspace for unveiling cellular diversity and objectively identifying biomarkers in large immune monitoring studies.FlowCT identified T-cell biomarkers predictive of malignant transformation and survival in SMM and active MM data sets.

Smoldering Multiple MyelomaOncologymedicine.medical_specialtyImmunobiology and ImmunotherapyT cellMyeloma2423ImmunophenotypingImmune systemMaintenance therapyBone MarrowInternal medicineHumansMedicineBiomarker discoveryMultiple myelomaCancer immunologybusiness.industryHematologymedicine.diseaseFlow Cytometrymedicine.anatomical_structureSmouldering myelomaBone marrowbusinessBiomarkersmyeloma flow cytometry single cell smouldering myeloma
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The Role of Internal and External Stakeholders

2015

The importance attributed to stakeholder issues in contemporary higher education affairs across the globe is a reflection of the changing nature of the social pact between higher education and society, brokered via the state, with new notions of trust and accountability as well as responsiveness to societal needs and demands as key attributes. This chapter takes stock of the key findings across the BRICS as per the individual contributions presented in part III of this volume.

Social PactHigher educationbusiness.industryStakeholderGlobePublic relationsPart iiimedicine.anatomical_structurePolitical scienceAccountabilitymedicinebusinessStakeholder theoryStock (geology)
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Measuring expectation for an affordance gap on a smartphone user interface and its usage among older adults

2020

The smartphone has become a ubiquitous mobile communication tool that plays a crucial role in the daily lives for Malaysian older adults. However, it is not easy for older adults to learn new interaction modes and adopt the smartphone user interface. In this paper, we aim to examine the affordances of a smartphone user interface and its usage by older adults through the lens of Norman’s execution/evaluation action cycle (EEAC) framework. A mobile-user interaction study was administered with four tasks. A paired sample t-test was conducted to analyze the affordance gap between different levels of expectation. The results revealed that three tasks (making phone calls, adding contacts, and usi…

Social Psychologybusiness.industryComputer scienceCommunicationMobile appsexecution/evaluation action cyclekäyttöaffordanceThrough-the-lens meteringälypuhelimetHuman-Computer InteractionPaired samplesPhoneHuman–computer interactionodotuksetsmartphone user interfaceMobile telephonyEvaluation - actionUser interfacebusinessAffordanceexpectationolder adultsaikuiset
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Can we improve emotional skills in older adults?. Emotional intelligence, life satisfaction, and resilience

2020

ABSTRACT Emotional intelligence has been shown to be a relevant resource associated with better personal and social adaptation. In older adults, it has been associated with constructs such as life satisfaction and resilience, which are of interest in the field of gerontology because of their impact during the aging process. The objective of this study is to test an intervention based on emotional intelligence in order to find out whether the levels of these abilities improve, and whether the intervention has an effect on resilience and life satisfaction. The sample was composed of 125 healthy older adults (treatment, n = 57 and control, n = 68). The variables studied were homogeneous betwee…

Social Psychologymedia_common.quotation_subjectlcsh:BF1-990Psychological intervention050109 social psychologyInterventionemotional intelligencelaw.inventionTreatment and control groupslawIntervention (counseling)Developmental and Educational Psychology0501 psychology and cognitive sciencesresiliencelife satisfactionApplied Psychologyolder adultsinterventionmedia_commonResilienceEmotional intelligence05 social sciencesLife satisfactionCognitionlcsh:PsychologyEmotional intelligenceOlder adultsCLARITYLife satisfactionPsychological resiliencePsychology050104 developmental & child psychologyClinical psychology
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The organizational use of online stock photos: The impact of representing senior citizens as eternally youthful

2018

The digital divide due to age is declining quickly. But this does not necessarily mean that the willingness to use stock photos depicting older people accompanying digital information is the same among all senior citizens. Three research questions are at the core of this paper: (1) To which extent can various senior citizens (women and men, younger old and older old, living alone or together, full of vitality or fragile) identify with online stock photos of older people accompanying information about pensions, income, health and housing?, (2) Which are the connotations of the visual signs used in such stock photos? and (3) What are the policy implications for organizations aiming at offerin…

Social Psychologyvanhukset050801 communication & media studiesonline stock photosVitality03 medical and health sciences0508 media and communications030502 gerontologySociologyDigital dividetunnistaminenvalokuvatsenior citizensStock (geology)business.industryCommunication05 social sciencesvisuaalinen viestintäPublic relationsHuman-Computer InteractionWillingness to useidentificationvisual ageismResearch questionsverkkoviestintä0305 other medical sciencebusinessOlder peopleHuman Technology
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Older people’s dialogue about loneliness and social support: a cross-cultural qualitative study conducted in Spain and South Africa (Diálogo entre la…

2021

This study aimed to explore and gain insight from the dialogue and subjective perception of older people about loneliness and social support using a cross-cultural approach. A total of six focus gr...

Social supportSocial PsychologySubjective perceptionmedicineLonelinessmedicine.symptomPsychologyOlder peopleSocial psychologyInternational Journal of Social Psychology
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Social responsibility and welfare of elderly people

2018

Este artículo muestra algunos de los resultados del estudio realizado entre el 2012 y 2015 en dos contextos, Colombia y España, cuyo objetivo fue conocer la realidad social de un segmento de mercado en crecimiento y la importancia de las políticas gubernamentales y sociales vigentes para la protección y calidad de vida de la población adulta mayor. Se definen las variables, estructuran y aplican tres encuestas estructuradas y un cuestionario, resaltando las residencias como punto de partida y los diferentes públicos involucrados: adultos mayores, familiares, directivos de centros residenciales y expertos en el tema, compilando información primaria y secundaria referente al hogar/residencia …

Social welfareEconomics and EconometricsResponsabilidad socialSocial economySociology and Political ScienceUNESCO::CIENCIAS ECONÓMICASSocial responsibility:CIENCIAS ECONÓMICAS [UNESCO]Older AdultsAdulto mayorElderlyTrabajo social con ancianosBienestar socialSocial work with older peopleTercer sectorEconomía social
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