Search results for "onkologia"
showing 3 items of 3 documents
Psychological correlates of physical activity and exercise preferences in metropolitan and nonmetropolitan cancer survivors
2021
Objective Interventions to increase physical activity (PA) in cancer survivors have often adopted a ‘one‐size‐fits‐all’ approach, and may benefit from being tailored to psychological constructs associated with behavior. The study objective was to investigate the exercise preferences and psychological constructs related to PA among cancer survivors. Methods Post‐treatment colorectal, endometrial, and breast cancer survivors (n=183) living in metropolitan and non‐metropolitan areas completed survey measures of PA, exercise preferences, attitudes, self‐efficacy, perceived behavioral control (PBC), and intention toward PA. Results A structural equation model with adequate fit and quality indice…
Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
2023
AbstractTheoretical and applied cancer studies that use individual-based models (IBMs) have been limited by the lack of a mathematical formulation that enables rigorous analysis of these models. However, spatial cumulant models (SCMs), which have arisen from theoretical ecology, describe population dynamics generated by a specific family of IBMs, namely spatio-temporal point processes (STPPs). SCMs are spatially resolved population models formulated by a system of differential equations that approximate the dynamics of two STPP-generated summary statistics: first-order spatial cumulants (densities), and second-order spatial cumulants (spatial covariances).We exemplify how SCMs can be used i…
Resectability, conversion, metastasectomy and outcome according to RAS and BRAF status for metastatic colorectal cancer in the prospective RAXO study
2022
Abstract Background Outcomes after metastasectomy for metastatic colorectal cancer (mCRC) vary with RAS and BRAF mutational status, but their effects on resectability and conversion rates have not been extensively studied. Methods This substudy of the prospective RAXO trial included 906 patients recruited between 2011 and 2018. We evaluated repeated centralised resectability assessment, conversion/resection rates and overall survival (OS), according to RAS and BRAF status. Results Patients included 289 with RAS and BRAF wild-type (RAS and BRAFwt), 529 with RAS mutated (RASmt) and 88 with BRAF mutated (BRAFmt) mCRC. Metastatic prevalence varied between the RAS and BRAFwt/RASmt/BRAFmt groups,…