Search results for "operation"

showing 10 items of 2969 documents

Early Mortality in Patients with Multiple Myeloma Treated with Novel Agents - Analysis from Polish Myeloma Study Group

2020

Background Although the introduction of novel agents improved the survival outcomes in patients with multiple myeloma (MM), some patients died within one year (early mortality, EM) following diagnosis. In this study, we evaluated the EM rate, and investigated the risk factors associated with EM in MM patients. Aims In this study we investigated risk factors associated with EM in MM patients initially treated with novel-agent containing regimen. Methods We conducted a multicenter (15 Polish sites) retrospective study a cohort of symptomatic MM pts diagnosed between October 2006 and November 2019 and living < 365 days (d) after diagnosis. All pts were dead at the time of the analysis. …

medicine.medical_specialtybusiness.operationbusiness.industryImmunologyRetrospective cohort studyCell BiologyHematologymedicine.diseaseOctapharmaBiochemistryThalidomideRegimenNovel agentsInternal medicineCohortMedicineIn patientbusinessMultiple myelomamedicine.drugBlood
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Health Policy Model: Long-Term Predictive Results Associated with the Management of HCV-Induced Diseases in Italy

2014

Background: This study is aimed at describing the epidemiological and economic burden that HCV will generate in the next few years in Italy. Furthermore, the impact that future anti-HCV treatments may have on the burden of disease was considered. The analysis has been developed over the period 2013-2030 from the Italian National Health Service (NHS) perspective.Methods: A published system dynamic model was adapted for Italy in order to quantify the HCV-infected population, the disease progression and the associated cost from 1950 to 2030. The model structure was based on transition probabilities reflecting the natural history of the disease. In order to estimate the efficacy of current anti…

medicine.medical_specialtyeducation.field_of_studybusiness.industryPopulationTelaprevirlaw.inventionClinical trialchemistry.chemical_compoundRandomized controlled trialchemistrylawBoceprevirHealth careEmergency medicineEpidemiologymedicineOperations managementbusinesseducationHealth policymedicine.drugSSRN Electronic Journal
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Use of digital displays and ocular surface alterations: A review.

2020

Digital display use has been accepted to be implicated as a contributing factor for dry eye disease (DED). Abnormal blinking during computer operation, including a reduced blink rate and an incomplete eyelid closure, increased palpebral fissure as consequence of high visualization angles, and meibomian gland dysfunction associated to long-term display use, are behind the increased prevalence of dry eye signs and symptoms found in digital display users. Previous research reveals significant reductions in tear volume and stability, alterations in tear film composition, including increased osmolarity, inflammatory cytokines, oxidative stress markers and reduced mucin secretion, eyelid abnormal…

medicine.medical_specialtygenetic structuresSigns and symptomsDiseaseTear volume03 medical and health sciences0302 clinical medicineOphthalmologyMedicineHumansBlinkingbusiness.industryComputer vision syndromeMeibomian Glandsmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structurePalpebral fissureTears030221 ophthalmology & optometryEyelid DiseasesDry Eye SyndromesFemalesense organsEyelidComputer OperationbusinessOcular surfaceConjunctiva030217 neurology & neurosurgeryThe ocular surface
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Managing Peripheral Artery Disease in Diabetic Patients: A Questionnaire Survey from Vascular Centers of the Mediterranean Federation for the Advanci…

2020

Background The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded on October 1, 2018, to enhance cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic arteriopathy has been selected as the very first topic to be investigated by the federation. Methods MeFAVS members were asked to reply to a questionnaire on the management of diabetic ischemic foot. Results were collected and analyzed statistically. The questionnaire consisted of 15 multiple choice answers regarding diabetic foot (DF) diagnosis and treatment. The questionnaire was submitted to 21 centers on…

medicine.medical_treatmentPsychological intervention030204 cardiovascular system & hematologyvascular surgerySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imagingWound care0302 clinical medicineIschemiaPractice Patterns Physicians'Response rate (survey)Practice Patterns Nurses'diabetesMediterranean RegionEndovascular Proceduresvascular medicineGeneral MedicineTreatment OutcomeCardiology and Cardiovascular MedicineVascular Surgical Proceduresdiabetic footmanagementSpecializationReoperationmedicine.medical_specialtyRevascularizationNurse's RoleAmputation Surgical03 medical and health sciencesperipheral arterial diseaseMediterranean Seamedicineperipheral arterial disease; diabetes; vascular medicine; vascular surgeryHumansTrainingHealthcare DisparitiesEndovascular Surgery; Mediterranean Sea; Training; Vascular SurgeryPhysician's RolePatient Care TeamWound Healingbusiness.industryGeneral surgeryVascular surgerymedicine.diseaseDiabetic footAmputationHealth Care SurveysOrthopedic surgeryEndovascular SurgerySurgerybusinesswound careAnnals of Vascular Surgery
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External knowledge sourcing for R&D activities: antecedents and implications of governance mode choice

2014

This paper investigates how internal and external factors affect the choice between alliances and joint ventures (A&JVs) and mergers and acquisitions (M&As) for the external sourcing of research and development (R&D) activities, and whether or not such a choice is really con- tingent, that is, is it the best choice in terms of its impact on firms’ innovative performance under those circumstances? We build a set of hypotheses based on both the transaction-cost theory and the resource-based view, and test them through a secondary data source analy- sis. We found that companies adopt either R&D M&A or A&JV depending on internal (e.g. resources and capabilities, innovation experience) and exter…

mergers and acquisi- tioninnovative performanceStrategy and ManagementCorporate governanceexternal knowledge sourcingManagement Science and Operations ResearchContingency approachSettore ING-IND/35 - Ingegneria Economico-GestionaleAffect (psychology)Test (assessment)contingency approachResource (project management)alliances and joint ventureMergers and acquisitionsBusinessMarketingMode choiceSet (psychology)Industrial organizationTechnology Analysis & Strategic Management
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Informační operace

2017

The author of this article points out various issues in information management of information operations. To ensure the attainment of high security it is essential to maintain and develop the information system to implement new technologies for the needs of conducted military operations. In the environment of the terrorism threat, is the need for developing IO; means of communication, identification elements, components for conducting intelligence, special and reconnaissance operations

military environmentinformation operationssecurity systeminformation
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Informační operace

2016

The author of this article points out various issues in information management of information operations. To ensure the attainment of high security it is essential to maintain and develop the information system to implement new technologies for the needs of conducted military operations. In the environment of the terrorism threat, is the need for developing IO; means of communication, identification elements, components for conducting intelligence, special and reconnaissance operations.

military environmentinformation operationssecurity systeminformation
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NATO intervention in the light of the serbian-albanian war over Kosovo

2019

The author of this paper will present the circumstances of the NATO attack on Yugoslavia in 1999. The main goal of this address will be to show historical conditions of the Serbian-Albanian conflict over Kosovo, which led to the escalation of violence in this Serbian province. Moreover, the proofs will be shown that information about ethnic cleansing allegedly perpetrated by the Serbs in Kosovo were fabricated and they were the main cause of a decision made by NATO about the attack. NATO intervention was described in the subject literature in the West as a military operation and the “first warin history for the rights of man”. The author of this paper shall present an analysis exposing this…

military operationKosovo Liberation Armyethnic conflictKosovoNATO intervention
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Violenze “di genere” e violenze “sulle donne”: problemi di definizione e di rilevazione empirica

2020

Il capitolo punta a problematizzare gli aspetti definitori del concetto di “violenza di genere” e quelli legati più strettamente alla sua rilevazione/misurazione, cercando di fornire un contributo all’utilizzo delle statistiche sul tema in maniera avveduta e consapevole. The chapter aims to problematize the defining aspects of the concept of "gender violence" and those related more closely to its detection / measurement, trying to provide a contribution to the use of statistics on the subject in a prudent and conscious manner.

misurazioneGender-based violenceviolenza sulle donneviolence against womenViolenza di generedefinizione operativameasurementoperational definitionSettore SECS-S/05 - Statistica Sociale
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Modelización de riesgos climáticos y sistemas de vigilancia y alerta en la Comunitat Valenciana

2013

El primer objetivo de esta Tesis está relacionado con el desarrollo e implementación de diferentes sistemas de vigilancia y alerta para el territorio de la Comunitat Valenciana: un sistema de predicción meteorológica en tiempo real basado en el modelo atmosférico de mesoescala Regional Atmospheric Modeling System (RAMS) y un sistema de previsión del Índice UV (UVI), basado en el modelo Santa Barbara DISORT Atmospheric Radiative Transfer (SBDART). Además, se propone una metodología que proporciona un entorno computacional adecuado para la administración y coordinación de los diferentes procesos implicados en ambos sistemas de vigilancia. La principal mejora de la predicción UVI es la utiliza…

modelización numéricaoperational forecastingclimate risk:MATEMÁTICAS::Ciencia de los ordenadores [UNESCO]:CIENCIAS DE LA TIERRA Y DEL ESPACIO::Meteorología [UNESCO]UNESCO::CIENCIAS DE LA TIERRA Y DEL ESPACIO::Meteorologíaprogramming languagesUNESCO::MATEMÁTICAS::Ciencia de los ordenadoresconvective parameterization schemesUV IndexSBDART modelparametrización convectivaUNESCO::CIENCIAS DE LA TIERRA Y DEL ESPACIO::Climatología:CIENCIAS DE LA TIERRA Y DEL ESPACIO::Ciencias de la atmósfera [UNESCO]monitorización de procesosradiación eritemáticameteorología mesoscalar:CIENCIAS DE LA TIERRA Y DEL ESPACIO::Climatología [UNESCO]erythemal radiationmesoscale modelingheavy rain eventsnumerical modelingnatural hazardssistemas de vigilancia y alertaRAMS modelprecipitaciones intensasriesgos climáticosflash floodUNESCO::CIENCIAS DE LA TIERRA Y DEL ESPACIO::Ciencias de la atmósfera
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