Search results for "orage"

Snapshot multi-spectral-line imaging for applications in dermatology and forensics

2019

Performance of multi-spectral imaging critically depends on image acquisition time and working spectral bandwidths. Ultimate performance can be achieved if a set of monochromatic (single-wavelength) spectral images is obtained by a single snapshot - a technique provisionally called “snapshot multi-spectral-line imaging” or SMSLI. The SMSLI principle and the developed prototype devices for 3, 4 and 5 spectral line snapshot imaging are described. Two potential practical applications of SMSLI are discussed – for fast mapping of the main in-vivo skin chromophores and for detection of counterfeit banknotes and documents.

Laser illumination designs for snapshot multi-spectral-line imaging

2019

For multi-spectral imaging, both acquisition time of the spectral image set and the spectral bandwidth of each image have to be minimized. Ultimate performance can be achieved if the set of monochromatic (single-wavelength) spectral images is obtained with a single snapshot — a technique provisionally called "snapshot multi-spectral-line imaging" or SMSLI. Using contemporary RGB colour cameras, up to three spectral line images can be extracted from a snapshot image data cube at specific illumination that comprises only three spectral lines, each of them positioned within one of the detection bands (R, G or B) [1]. Techniques able to provide more spectral line images are under development, a…

Single snapshot RGB multispectral imaging at fixed wavelengths: proof of concept

2014

A concept of single snapshot multispectral imaging by standard RGB image sensors under spectrally-specific illumination comprising a fixed number of narrow spectral lines is discussed and experimentally validated. The limiting conditions, RGB band spectral crosstalk corrections and potential applications for parametric mapping of skin are regarded, along with the preliminary results of the proof-of-concept measurements.

Plant sterols from foods in inflammation and risk of cardiovascular disease: a real threat?

2014

High dietary intakes of cholesterol together with sedentary habits have been identified as major contributors to atherosclerosis. The latter has long been considered a cholesterol storage disease; however, today atherosclerosis is considered a more complex disease in which both innate and adaptive immune-inflammatory mechanisms as well as bacteria play a major role, in addition to interactions between the arterial wall and blood components. This scenario has promoted nutritional recommendations to enrich different type of foods with plant sterols (PS) because of their cholesterol-lowering effects. In addition to cholesterol, PS can also be oxidized during food processing or storage, and the…

Metabolism of rat liver cells during incubation in cold UW solution

1997

Simple cold storage of livers for transplantation activates glycolysis due to lack of oxygen. Energy derived from glycolysis may be critical for cell survival and liver cell death may occur once glycolysis is inhibited in the liver due to accumulation of end products or lack of substrates (glycogen). The relationship between cell death (lactate dehydrogenase, LDH release), anaerobic glycolysis (lactate production), and glycogen content of liver tissue was studied during cold incubation of liver slices in UW solution. Rat livers slices from male Sprague Dawley rats were incubated at 4 degrees C in UW solution, with continuous gentle shaking, under conditions of chemical hypoxia (KCN, 5 mM). …

Critical assessment of chitotriosidase analysis in the rational laboratory diagnosis of children with Gaucher disease and Niemann-Pick disease type A…

2006

Laboratory diagnosis of lysosomal storage disorders, especially sphingomyelinase deficiency (Niemann–Pick disease type A/B) and Niemann–Pick disease type C (NPC) can be challenging. We therefore aimed to analyse the feasibility of first-step screening with specific chitotriosidase cut-off values in children ≤ 10 years of age with visceral organomegaly (hepatomegaly, splenomegaly, or hepatosplenomegaly) in whom a storage disorder was suspected. We conducted a retrospective, cross-sectional, referral, single-centre study to assess diagnostic test properties in 106 individuals. Median chitotriosidase activity was 12 655 nmol/h per ml (interquartile range 4693–20982) in Gaucher disease (GD); 78…

Comment: Why are females with Fabry disease affected?

2019

Anderson‐Fabry Disease: A Rare Cause of Levodopa‐Responsive Early‐Onset Parkinsonism

2021

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3×3 Technique for RGB Snapshot Mapping of Skin Chromophores

2015

Three monochromatic spectral images have been extracted from a single RGB image data set at simultaneous illumination of skin by 473nm, 532nm and 609nm spectral lines. They were further transformed into distribution maps of three skin chromophores - melanin, oxy-hemoglobin and deoxy-hemoglobin, related to pigmented and vascular skin malformations. Performance and clinical potential of the proposed 3×3 technique is discussed.

Gadolinium accumulation after contrast-enhanced magnetic resonance imaging: Which implications in patients with Crohn's disease?

2017

Crohn's disease (CD) is a chronic inflammatory condition of the bowel, characterized by an alternation of remission and relapse phases, leading to a progressive intestinal damage with loss of function. Magnetic resonance enterography has been widely used in the past for the evaluation of fistulizing disease, but its use increased over time, being considered helpful in different moments of disease course. Intravenous injection of Gadolinium-based contrast agents has been demonstrated to be crucial to assess mucosal inflammation, transmural involvement, and extraintestinal disease. Recently, Gadolinium accumulation in human tissues has been increasingly reported, although clinical implication…