Search results for "oral lichen planus"

showing 10 items of 111 documents

A report on the clinical-pathological correlations of 788 gingival lesion

2017

Background The diagnosis and treatment of a variety of non-plaque related gingival diseases have become an integrated aspect of everyday dentistry. The aim of this study was to analyse the relationship between clinical appearance and histopathological features of gingival lesions in a large Northern Italian population. Material and Methods A retrospective study of 788 cases of gingival and alveolar mucosal biopsies was set up. Statistical analysis was performed by calculating the odds ratio and 95% confidence interval (C.I.), in order to assess the degree of association between the clinical parameters considered (primary lesions) and the single pathologies, statistically evaluated by Mantel…

Malemedicine.medical_specialtyEpulisHistological analysis2734Pathology and Forensic MedicineLesion03 medical and health sciences0302 clinical medicinemedicineHumansGeneral DentistryLeukoplakiaRetrospective StudiesOral Medicine and Pathologybusiness.industryVerrucous carcinomaPyogenic granulomaResearchOtorhinolaryngology2734 Pathology and Forensic Medicine030206 dentistryMiddle Agedmedicine.diseaseGingival lesions:CIENCIAS MÉDICAS [UNESCO]DermatologyClinical appearance; Clinico-pathological correlation; Gingival lesions; Histological analysis; Surgery; Otorhinolaryngology2734 Pathology and Forensic Medicine; Dentistry (all)Clinical appearanceOtorhinolaryngologyItaly030220 oncology & carcinogenesisGingival DiseasesUNESCO::CIENCIAS MÉDICASClinical appearance; Clinico-pathological correlation; Gingival lesions; Histological analysis; Surgery; Otorhinolaryngology; 2734; Pathology and Forensic Medicine; Dentistry (all)Dentistry (all)HistopathologyOral lichen planusFemaleSurgeryClinico-pathological correlationmedicine.symptombusinessGingival disease
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Oral lichen planus: a retrospective study of 633 patients from Bucharest, Romania

2012

Objective: In this retrospective study, patients’ medical records were reviewed to investigate the profiles of 633 OLP cases in a group of Romania. Material and Methods: In this retrospective study, the following clinical data were obtained from the medical charts of patients: gender, age, clinical presentation of OLP, site affected, presence of symptoms, extraoral manifestations of lichen planus, presence of systemic diseases, and history of medications. Results: Most (78.67%) OLP patients were female and the mean age at presentation was 52 years. The white type of the disease (reticular/papular/plaque lesions) was the main form encountered in this sample (48.97%). Among patients with avai…

Malemedicine.medical_specialtyHepatitis C virusPopulationGallbladder diseaseOdontologíaDiseasemedicine.disease_causestomatognathic systemmedicineHumanseducationGeneral DentistryAgedRetrospective Studieseducation.field_of_studyOral Medicine and Pathologybusiness.industryRomaniaMedical recordRetrospective cohort studymedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludSurgerystomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASCholecystitisSurgeryOral lichen planusResearch-ArticleFemalebusinessLichen Planus Oral
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Scoring systems for Oral Lichen Planus used by differently experienced raters

2017

BACKGROUND: Scoring systems have been widely used to evaluate the severity and activity of oral lichen planus (OLP). The aim of the present study was to compare two existing (one modified) scoring systems in the evaluation of OLP severity and correlation with pain. Three differently experienced raters were involved. MATERIALS AND METHODS: Consecutive patients with OLP were assessed for pain using the Visual Analogue Scale and examined at 10 intraoral sites before starting (T0) and three weeks after (T1) steroid therapy (Clobetasol). Three differently experienced raters evaluated photographs using two scoring systems designated White-Erosive-Atrophic (WEA) modified from an older WEA system (…

Malemedicine.medical_specialtyIntraclass correlationVisual analogue scalePainraterBuccal mucosaSpearman's rank correlation coefficientSeverity of Illness Index03 medical and health sciences0302 clinical medicineSeverity of illnessOral and maxillofacial pathologymedicineHumansGeneral DentistryGlucocorticoidsUNESCO:CIENCIAS MÉDICASPain MeasurementClobetasolOral Medicine and Pathologybusiness.industryResearchscoring system030206 dentistryMiddle Agedmedicine.diseaseDermatologyWEAstomatognathic diseasesOtorhinolaryngologyOral lichen planu030220 oncology & carcinogenesisClobetasolOral lichen planusSurgeryOral lichen planusFemaleVASbusinessOral lichen planus; scoring system; VAS; REU; WEA; raterREULichen Planus Oral
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Topical treatment of oral lichen planus with anthocyanins

2014

Background: Oxidative stress is involved in oral lichen planus (OLP) pathogenesis; meanwhile anthocyanins are natural antioxidants present in grapes skin. Objectives: The aim of this research was to verify the utility of anthocyanins, extracted from grapes skin, for the local treatment of oral lichen planus and to compare it with clobetasol propionate- neomycin -nystatin cream (CP-NN). Study Design: Prospective, non-randomized study, with control group. Fifty-two patients with OLP were includ - ed. We divided patients into two categories: erosive oral lichen planus (EOLP) and non erosive oral lichen planus (NEOLP). 38 had EOLP (17 cases and 21 controls) and 14 presented NEOLP types (9 cases…

Malemedicine.medical_specialtyNystatinAdministration TopicalTopical treatmentOdontologíamedicine.disease_causeAnthocyaninsstomatognathic systemmedicineHumansProspective StudiesOral mucosaProspective cohort studyGeneral DentistryClobetasolOral Medicine and Pathologybusiness.industryResearchSignificant differencefungifood and beveragesNeomycinMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludSurgeryDrug Combinationsstomatognathic diseasesmedicine.anatomical_structureNystatinOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryOral lichen planusFemaleClobetasol propionatebusinessOxidative stressmedicine.drugLichen Planus Oral
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Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

2021

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, pre…

Medicine (General)medicine.medical_specialtyClinical Biochemistryoral mucous membrane pemphigoidR5-920Immune systemOptical coherence tomographyMedicineskin and connective tissue diseasesPathologicaloptical coherence tomographyintegumentary systemmedicine.diagnostic_testbusiness.industryBrief Reportoral pemphigus vulgarisPemphigus vulgarisOral pemphigus vulgarismedicine.diseaseDermatologydesquamative gingivitiseye diseasesDesquamative gingivitisstomatognathic diseasesMucous membrane pemphigoidDesquamative gingivitis Optical coherence tomography Oral mucous membrane pemphigoid Oral pemphigus vulgarisOral lichen planusbusinessDiagnostics
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Human papillomaviruses in oral carcinoma and oral potentially malignant disorders: a systematic review

2011

Oral Diseases (2011) 17 (Suppl. 1), 58–72 Objectives:  Human papillomavirus (HPV) in oral carcinoma (OSCC) and potentially malignant disorders (OPMD) is controversial. The primary aim was to calculate pooled risk estimates for the association of HPV with OSCC and OPMD when compared with healthy oral mucosa as controls. We also examined the effects of sampling techniques on HPV detection rates. Methods:  Systematic review was performed using PubMed (January 1966–September 2010) and EMBASE (January 1990–September 2010). Eligible studies included randomized controlled, cohort and cross-sectional studies. Pooled data were analysed by calculating odds ratios, using a random effects model. Risk o…

OncologyEpithelial dysplasiaErythroplakiamedicine.medical_specialtyPathologybusiness.industryOdds ratiomedicine.diseasestomatognathic diseasesOtorhinolaryngologyMeta-analysisInternal medicineMedicineOral lichen planusbusinessProspective cohort studyGeneral DentistryLeukoplakiaCohort studyOral Diseases
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Angiogenesis of oral lichen planus: a possible pathogenetic mechanism.

2008

Objective: Oral Lichen Planus (OLP) is a chronic inflammatory disease with an autoimmune inflammatory pathogenesis. The aim of the research is to compare the vascular endothelial growth factor (VEGF) and adhesion of molecules in the biopsy samples of patients affected by OLP, in order to research the presence of the angiogenetic phenomenon and to understand its pathogenetic mechanism. Materials and Methods: Thirty OLP patients and thirty healthy subjects were enrolled in a study. The immunohistochemical analysis of the VEGF and vascularendothelial adhesion molecules was carried out by means of primary antibodies and anti-CD34, anti-VEGF, antiCD106 antigen (VCAM-1) and anti-CD54 antigen (ICA…

Oral Lichen Planus angiogenesis immunohistochemical VEGF VCAM-1 ICAM-1.MalePathologymedicine.medical_specialtyAngiogenesisCD34Neovascularizationchemistry.chemical_compoundAntigenstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheBiopsyMedicineHumansGeneral Dentistrymedicine.diagnostic_testNeovascularization Pathologicbusiness.industryMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Vascular endothelial growth factorstomatognathic diseasesOtorhinolaryngologychemistryUNESCO::CIENCIAS MÉDICASImmunohistochemistrySurgeryOral lichen planusFemalemedicine.symptombusinessLichen Planus OralMedicina oral, patologia oral y cirugia bucal
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Oral Lichen Planus: a new experimental therapeutic protocol by means of oxygen-ozone mixture injection.

2019

Oral Lichen Planus therapeutic protocol oxygen-ozone mixture injection.
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Quality of life in erosive oral lichen planus patients treated with clobetasol mucoadhesive formulations – a pilot study

2017

Oral lichen planus OLP Clobetasol quality of life
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Where do you live? North versus Central-South differences in relation to Italian patients with oral lichen planus: a cross-sectional study from the S…

2022

Abstract Background Oral lichen planus (OLP) is an immune-mediated inflammatory chronic disease of the oral mucosa, with different patterns of clinical manifestations which range from keratotic manifestations (K-OLP) to predominantly non-keratotic lesions (nK-OLP). The aim of the study was to analyze the differences in the clinical, psychological profile and symptoms between Italian patients of the North and Central-South with K-OLP and nK-OLP. Methods 270 K-OLP and 270 nK-OLP patients were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality In…

OralCross-Sectional StudieLichen PlanusItaly; Oral lichen planus; Pain; Psychological profile; Sleep disturbancesSleep disturbancePainSleep disturbancesAnxietySettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHECross-Sectional StudiesOral lichen planuItalyPsychological profileItaly; Oral lichen planus; Pain; Psychological profile; Sleep disturbances; Anxiety; Cross-Sectional Studies; Humans; Pain; Pathology Oral; Lichen Planus OralOral lichen planusPathologyPathology OralHumansGeneral DentistryHumanLichen Planus Oral
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