Search results for "organizing"

showing 10 items of 113 documents

Immune-checkpoint inhibitors in non-small cell lung cancer: A tool to improve patients’ selection

2018

The identification of reliable predictive biomarkers of efficacy or resistance to immune-oncology (I–O) agents is a major issue for translational research and clinical practice. However, along with PDL1 and molecular features other clinical, radiological and laboratory factors can be considered for the selection of those patients who would not be the best candidate for immune-checkpoint inhibitors (ICPIs). We examined these factors, emerging from the results of currently available studies in non-small cell lung cancer (NSCLC), aiming to provide a useful and manageable tool which can help Oncologists in their everyday clinical practice. A thorough patient evaluation and close clinical monito…

0301 basic medicineOncologymedicine.medical_specialtyLung NeoplasmsImmune-checkpoint inhibitorSettore MED/06 - Oncologia MedicaImmune-checkpoint inhibitorsBiomarkers; Immune-checkpoint inhibitors; Immune-oncology; Non-small cell lung cancer; Predictive factors; Antibodies Monoclonal; B7-H1 Antigen; Biomarkers; CTLA-4 Antigen; Carcinoma Non-Small-Cell Lung; Humans; Immunotherapy; Lung Neoplasms; Patient Selection; Hematology; OncologyAntibodiesB7-H1 Antigen03 medical and health sciences0302 clinical medicineNon-small cell lung cancerCarcinoma Non-Small-Cell LungInternal medicineMonoclonalmedicineHumansCTLA-4 AntigenNeutrophil to lymphocyte ratioNon-Small-Cell LungLung cancerHepatitisPerformance statusbusiness.industryPatient SelectionCarcinomaInterstitial lung diseaseAntibodies MonoclonalBronchiolitis obliterans organizing pneumoniaBiomarkerHematologymedicine.diseaseBiomarkers; Immune-checkpoint inhibitors; Immune-oncology; Non-small cell lung cancer; Predictive factors; Hematology; OncologyClinical trial030104 developmental biologyOncology030220 oncology & carcinogenesisImmunotherapyPredictive factorbusinessBiomarkersImmune-oncologyPredictive factorsProgressive diseaseCritical Reviews in Oncology/Hematology
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Multivariate statistical analysis of a large odorants database aimed at revealing similarities and links between odorants and odors

2017

International audience; The perception of odor is an important component of smell; the first step of odor detection, and the discrimination of structurally diverse odorants depends on their interactions with olfactory receptors (ORs). Indeed, the perception of an odor's quality results from a combinatorial coding, in which the deciphering remains a major challenge. Several studies have successfully established links between odors and odorants by categorizing and classifying data. Hence, the categorization of odors appears to be a promising way to manage odors. In the proposed study, we performed a computational analysis using odor descriptions of the odorants present in Flavor-Base 9th Edit…

0301 basic medicinemultidimensional scalingmedia_common.quotation_subjectAgglomerative hierarchical clusteringKohonen self-organizing mapsodorants03 medical and health sciences0302 clinical medicinePerceptionComputational analysisMultidimensional scalingmedia_commonChemistrybusiness.industrymusculoskeletal neural and ocular physiologyPattern recognitionKohonen self organizing mapGeneral Chemistrycategorization030104 developmental biologyCategorizationOdorodor notesagglomerative hierarchical clusteringArtificial intelligenceMultivariate statisticalbusiness[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgerypsychological phenomena and processesFood Science
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Ethnicity, 2009/1 : Politics of Recognition

2009

"Ethnicity" publishes original research papers on the problems of social sciences (sociology, political sciences, linguistics, social psychology, law, history), as well as review articles, information on conferences and scientific life.

:SOCIAL SCIENCES::Social sciences::Social anthropology/ethnography::Ethnography [Research Subject Categories]ethnic minoritytraditional ethnic minoritiesmultiethnic society:HUMANITIES and RELIGION::History and philosophy subjects::Ethnology [Research Subject Categories]interethnic dialogueorganizing education - Lithuania«The Jews in the Baltics. From the beginning of their arrival until the Holocaust. The 14th century – 1945» - book review
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Diagnosing fatigue in gait patterns by support vector machines and self-organizing maps

2009

The aim of the study was to train and test support vector machines (SVM) and self-organizing maps (SOM) to correctly classify gait patterns before, during and after complete leg exhaustion by isokinetic leg exercises. Ground reaction forces were derived for 18 gait cycles on 9 adult participants. Immediately before the trials 7-12, participants were required to completely exhaust their calves with the aid of additional weights (44.4±8.8kg). Data were analyzed using: (a) the time courses directly and (b) only the deviations from each individual's calculated average gait pattern. On an inter-individual level the person recognition of the gait patterns was 100% realizable. Fatigue recognition …

AdultMaleSelf-organizing mapmedicine.medical_specialtySupport Vector MachineWeight LiftingComputer scienceIndividualityBiophysicsExperimental and Cognitive PsychologyPattern Recognition AutomatedYoung AdultPhysical medicine and rehabilitationmedicineHumansOrthopedics and Sports MedicineGround reaction forceGaitArtificial neural networkMuscle fatiguebusiness.industryBiomechanicsGeneral MedicineGaitBiomechanical PhenomenaSupport vector machineNonlinear DynamicsMuscle FatiguePattern recognition (psychology)Artificial intelligencebusinesshuman activitiesHuman Movement Science
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Simulating Actions with the Associative Self-Organizing Map

2013

We present a system that can learn to represent actions as well as to internally simulate the likely continuation of their initial parts. The method we propose is based on the Associative Self Organizing Map (A-SOM), a variant of the Self Organizing Map. By emulating the way the human brain is thought to perform pattern recognition tasks, the A- SOM learns to associate its activity with di erent inputs over time, where inputs are observations of other's actions. Once the A-SOM has learnt to recognize actions, it uses this learning to predict the continuation of an observed initial movement of an agent, in this way reading its intentions. We evaluate the system's ability to simulate actions …

Associative Self-Organizing Map Neural Network Action Recognition Internal Simulation Intention Understanding
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Internal Simulation of an Agent’s Intentions

2013

We present the Associative Self-Organizing Map (A-SOM) and propose that it could be used to predict an agent’s intentions by internally simulating the behaviour likely to follow initial movements. The A-SOM is a neural network that develops a representation of its input space without supervision, while simultaneously learning to associate its activity with an arbitrary number of additional (possibly delayed) inputs. We argue that the A-SOM would be suitable for the prediction of the likely continuation of the perceived behaviour of an agent by learning to associate activity patterns over time, and thus a way to read its intentions.

Associative Self-Organizing Map; Internal Simulation;ContinuationArtificial neural networkbusiness.industryComputer scienceAssociative Self-Organizing MapRepresentation (systemics)Artificial intelligenceSpace (commercial competition)businessInternal SimulationAssociative property
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From Topology to Quasi-Topology. The Complexity of the Notional Domain

2016

This article examines a fundamental metalinguistic construction of the theory of enunciative operations: the notional domain. In particular, we try to explain some elementary topological concepts on which this construction is based and we try to show the key role they play in the description of some basic linguistic operations.

AttractorTopological spacePredicative expressionNotional amountTopologyTopology (chemistry)Notional Domain Topological Space Occurrences Organizing Centre AttractorsDomain (software engineering)Mathematics
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Class discovery from semi-structured EEG data for affective computing and personalisation

2017

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Many approaches to recognising emotions from metrical data such as EEG signals rely on identifying a very small number of classes and to train a classifier. The interpretation of these classes varies from a single emotion such as stress [24] to features of emotional model such as valence-arousal [4]. There are two major issues here. First classification approach limits the analysis of the data within the selected classes and is also highly dependent on training data/cycles, all of which limits generalisation. Second issue is that it does not exp…

Brain modelingComputer scienceFeature extraction02 engineering and technologyElectroencephalographyMachine learningcomputer.software_genrePersonalizationCorrelationDEAP03 medical and health sciences0302 clinical medicine0202 electrical engineering electronic engineering information engineeringmedicineCluster analysisAffective computingmedicine.diagnostic_testbusiness.industryElectroencephalographySelf-organizing feature mapsFeature extraction020201 artificial intelligence & image processingArtificial intelligenceEmotion recognitionbusinessClassifier (UML)computer030217 neurology & neurosurgery
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Why adopt ISO 9001 certification in hospitals? A case study of external triggers and sensemaking in an emergency department in Norway

2017

Abstract Background Certification and accreditation are widely used to achieve quality and safety in health care but are also questioned regarding their assumed effects. This is a challenge for policymakers and managers, since adoption of these regimes can have a circumstantial impact upon organizations. This study’s aim was to explore how external conditions catalyzed and triggered organizational change and internal sensemaking processes as part of an ISO 9001 certification process. Methods The study applied an explanatory single-case design, using a narrative approach, to retrospectively follow a sensemaking process in an emergency department in a Norwegian hospital undergoing ISO 9001 ce…

CertificationCertification:Medical disciplines: 700::Health sciences: 800 [VDP]accreditationHealth administration03 medical and health sciences0302 clinical medicineSensemakingHealth careISOMedicine030212 general & internal medicineQuality improvementSituational ethicsInstitutional theoryinstitutional theoryAccreditationOrganizingbusiness.industrylcsh:Public aspects of medicine030503 health policy & serviceslcsh:RA1-1270General MedicineSensemakingPublic relationsISO-sertifiseringVDP::Medisinske Fag: 700::Helsefag: 8000305 other medical sciencebusinessCertification and Accreditation
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Nanomagnetic Self-Organizing Logic Gates

2021

The end of Moore's law for CMOS technology has prompted the search for low-power computing alternatives, resulting in several promising proposals based on magnetic logic[1-8]. One approach aims at tailoring arrays of nanomagnetic islands in which the magnetostatic interactions constrain the equilibrium orientation of the magnetization to embed logical functionalities[9-12]. Despite the realization of several proofs of concepts of such nanomagnetic logic[13-15], it is still unclear what the advantages are compared to the widespread CMOS designs, due to their need for clocking[16, 17] and/or thermal annealing [18,19] for which fast convergence to the ground state is not guaranteed. In fact, i…

Class (computer programming)Technology and EngineeringCondensed Matter - Mesoscale and Nanoscale PhysicsComputer scienceSIGNAL (programming language)FOS: Physical sciencesGeneral Physics and AstronomyNAND gateNonlinear Sciences - Adaptation and Self-Organizing SystemsPhysics and AstronomyCMOSComputer engineeringLogic gateSIMULATIONMesoscale and Nanoscale Physics (cond-mat.mes-hall)Path (graph theory)Reversible computingddc:530Unconventional computingAdaptation and Self-Organizing Systems (nlin.AO)Hardware_LOGICDESIGN
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