Search results for "organometallics"

showing 7 items of 7 documents

Comparative chemistry of 18-electron Mo(II) and 17-electron Mo(III) compounds containing only carbon-based ligands

1998

International audience; The chemical reactivity of various kinetically stable isomers of compound CpMo(η3-C3H5)(η4-C4H6), 1, and its oxidation product [1]+, as well as the bis-allyl Mo(III) complex CpMo(η3-C3H5)2, 2, and the bis-diene Mo(II) complex [CpMo(η4-C4H6)2]+, 3, is reviewed. The inertness toward isomerization processes of the allyl and butadiene ligands in the Mo(II) complexes has allowed a study of the relative reactivity toward both electrophilic and nucleophilic addition processes as a function of coordination mode. The dependence of various reaction pathways on the metal oxidation state has also been investigated. Of particular interest is the discovery that the electronically …

Allyl ligands010402 general chemistry01 natural sciencesMedicinal chemistryCatalysisInorganic ChemistryMetalButadiene polymerizationOxidation stateMaterials ChemistryOrganic chemistryMolecule[CHIM.COOR]Chemical Sciences/Coordination chemistryReactivity (chemistry)Physical and Theoretical ChemistryButadiene dimerizationMolybdenumNucleophilic addition010405 organic chemistryChemistry0104 chemical sciencesvisual_artElectrophilevisual_art.visual_art_mediumParamagnetic organometallicsReactivity of coordinated ligandsIsomerizationCoordination Chemistry Reviews
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Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold(I) complexes featuring N-heterocycl…

2020

Experimental organometallic gold(I) compounds hold promise for anticancer therapy. This study reports the synthesis of two novel families of gold(I) complexes, including N1-substituted bis-N-heterocyclic carbene (NHC) complexes of general formula [Au(N1-TBM) 2]BF 4 (N1-TBM = N1-substituted 9-methyltheobromin-8-ylidene) and mixed gold(I) NHC-alkynyl complexes, [Au(N1-TBM)alkynyl]. The compounds were fully characterised for their structure and stability in aqueous environment and in the presence of N-acetyl cysteine by nuclear magnetic resonance (NMR) spectroscopy. The structures of bis(1-ethyl-3,7,9-trimethylxanthin-8-ylidene)gold(I), (4-ethynylpyridine)(1,9-dimethyltheobromine-8-ylidene)gol…

Circular dichroismStereochemistryAntineoplastic Agents010402 general chemistryG-quadruplexLigands01 natural sciencesBiochemistryInorganic Chemistrychemistry.chemical_compoundNeoplasmsMoietyGold(I) organometallicsHumansN-heterocyclic carbenesCancer010405 organic chemistryChemistryFluorescenceG-quadruplexes0104 chemical sciencesFörster resonance energy transferMCF-7 CellsBODIPYDrug Screening Assays AntitumorSelectivityCarbeneAlkynyl ligandsMethaneOrganogold Compounds
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C−C Cross-Couplings from a Cyclometalated Au(III) C∧ N Complex: Mechanistic Insights and Synthetic Developments

2021

Abstract In recent years, the reactivity of gold complexes was shown to extend well beyond π‐activation and to hold promises to achieve selective cross‐couplings in several C−C and C−E (E=heteroatom) bond forming reactions. Here, with the aim of exploiting new organometallic species for cross‐coupling reactions, we report on the Au(III)‐mediated C(sp2)−C(sp) occurring upon reaction of the cyclometalated complex [Au(CCH2N)Cl2] (1, CCH2N=2‐benzylpyridine) with AgPhCC. The reaction progress has been monitored by NMR spectroscopy, demonstrating the involvement of a number of key intermediates, whose structures have been unambiguously ascertained through 1D and 2D NMR analyses (1H, 13C, 1H‐1H CO…

Coordination sphereHeteroatom010402 general chemistry01 natural sciencesCatalysisReductive eliminationNMR spectroscopyNucleophilecross-couplingReactivity (chemistry)Full Paper010405 organic chemistryChemistry[CHIM.ORGA]Chemical Sciences/Organic chemistryOrganic Chemistryreductive eliminationGeneral ChemistryNuclear magnetic resonance spectroscopy[CHIM.CATA]Chemical Sciences/CatalysisFull PapersTransition state0104 chemical sciencesgold cyclometalated complexesCrystallographyZincSettore CHIM/03 - Chimica Generale E InorganicaGoldTwo-dimensional nuclear magnetic resonance spectroscopyorganometallics
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Half-sandwich molybdenum(III) compounds containing diazadiene ligands and their use in the controlled radical polymerization of styrene

2002

Abstract The reaction of CpMoCl2 with diazadiene ligands RNCHCHNR (R2dad) affords the corresponding paramagnetic complexes CpMoCl2(R2dad) (R=Ph, 1; p-Tol, 2; C6H3Pr2i-2,6, 3; and Pri, 4). All compounds have been characterized by EPR spectroscopy and have been investigated by cyclic voltammetry. They display one-electron oxidation and reduction processes, these being reversible or irreversible depending on the nature of R. The irreversibility of the reduction wave is due to a chemical follow-up process which consists of chloride loss from the reduced product. This phenomenon is suppressed in the presence of excess chloride in solution. An X-ray structure of 3 verifies the mononuclear na…

Nitroxide mediated radical polymerizationRadical polymerization010402 general chemistryPhotochemistry01 natural sciencesBiochemistryChlorideStyreneInorganic ChemistryLiving free-radical polymerizationchemistry.chemical_compoundCyclopentadienyl complexPolymer chemistryMaterials Chemistrymedicine[CHIM.COOR]Chemical Sciences/Coordination chemistryCyclopentadienylPhysical and Theoretical ChemistryControlled radical polymerizationMolybdenumDiazadiene ligands010405 organic chemistryChemistryOrganic Chemistry[CHIM.CATA]Chemical Sciences/Catalysis0104 chemical sciences[CHIM.POLY]Chemical Sciences/PolymersCobalt-mediated radical polymerizationPolymerizationParamagnetic organometallicsmedicine.drugJournal of Organometallic Chemistry
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Confined crystallization of a HKUST-1 metal–organic framework within mesostructured silica with enhanced structural resistance towards water

2017

A HKUST-1 metal–organic framework was crystallized in the NH2-modified mesostructured silica FDU-12 in order to improve its structural stability upon water exposure. In-depth structural characterization studies of the designed composite confirmed successful formation of the MOF phase within the ordered spherical mesopores of the silica matrix. In spite of the confinement within the cavities, MOF exhibits full accessibility for the adsorbed gas molecules. In contrast to the bulk HKUST-1, which undergoes slow phase transition in a humid environment, the structural integrity of the HKUST-1 in the humid-protective matrix remains unchanged even after immersion and stirring in water at elevated t…

Phase transitionMaterials scienceRenewable Energy Sustainability and the EnvironmentComposite numberEngineering controlled terms: Crystalline materialsOrganometallicsStability Compendex keywords Confined crystallizationElevated temperatureMesostructured silicaMetal organic frameworkSpherical mesoporesStructural characterizationStructural resistanceStructural stabilities Engineering main heading: SilicaNanotechnology02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical scienceslaw.inventionAdsorptionChemical engineeringlawPhase (matter)MoleculeGeneral Materials ScienceMetal-organic frameworkCrystallization0210 nano-technologyMesoporous material
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Rare‐earth cyclobutadienyl sandwich complexes: Synthesis, structure and dynamic magnetic properties

2018

The potassium cyclobutadienyl [K2{η4‐C4(SiMe3)4}] (1) reacts with MCl3(THF)3.5 (M=Y, Dy) to give the first rare‐earth cyclobutadienyl complexes, that is, the complex anions [M{η4‐C4(SiMe3)4}{η4‐C4(SiMe3)3‐κ‐(CH2SiMe2}]2−, (2M), as their dipotassium salts. The tuck‐in alkyl ligand in 2M is thought to form through deprotonation of the “squarocene” complexes [M{η4‐C4(SiMe3)4}2]− by 1. Complex 2Dy is a single‐molecule magnet, but with prominent quantum tunneling. An anisotropy barrier of 323(22) cm−1 was determined for 2Dy in an applied field of 1 kOe, and magnetic hysteresis loops were observed up to 7 K. nonPeerReviewed

magneettiset ominaisuudetcyclobutadienyl ligandsmagneetitchemistry.chemical_element010402 general chemistry01 natural sciencesCatalysisDeprotonationAnisotropyta116magnetsAlkylQuantum tunnellingchemistry.chemical_classificationkemiallinen synteesiorganometallics dysprosium010405 organic chemistryLigandOrganic ChemistrykompleksiyhdisteetGeneral Chemistryharvinaiset maametallitMagnetic hysteresis0104 chemical sciencesCrystallographychemistryMagnetDysprosiumsingle-moleculerare-earth elements
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A Theoretical and Experimental Investigation of the Spectroscopic Properties of a DNA-Intercalator Salphen-Type ZnIIComplex

2014

The photophysical and DNA-binding properties of the cationic zinc(II) complex of 5-triethylammonium methyl salicylidene ortho-phenylenediiminato (ZnL 2 + ) were investi- gated by a combination of experimental and theoretical methods. DFT calculations were performed on both the ground and the first excited states of ZnL 2 + and on its possi- ble mono- and dioxidation products, both in vacuo and in selected solvents mimicked by the polarizable continuum model. Comparison of the calculated absorption and fluores- cence transitions with the corresponding experimental data led to the conclusion that visible light induces a two-elec- tron photooxidation process located on the phenylenediimi- nato…

spectroscopyNO ligandStereochemistryIntercalation (chemistry)Ionic bondingmetal complex Fluorescence spectroscopy DNA recognition metal complexes organometallics complex formation DNA binding drugs fluorescence spectroscopy equilibrium constants reaction mechanisms nucleic acids affinity binding mode thermodynamics speciationmetal complexesbinding modePhenylenediaminesPolarizable continuum modelCatalysisdrugsmetal complexthermodynamicsintercalationcomplex formationOrganometallic CompoundsA-DNADNA bindingFluorescence spectroscopyDNA recognitionphotochemistryLigandChemistrySpectrum AnalysisphotooxidationOrganic ChemistryCationic polymerizationequilibrium constantsGeneral Chemistrydensity functional calculationFluorescenceZincCrystallographyreaction mechanismsnucleic acidsspeciationSettore CHIM/03 - Chimica Generale E InorganicaExcited stateaffinityfluorescenceorganometallics
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