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showing 10 items of 4356 documents

Estimating Heart Rate, Energy Expenditure, and Physical Performance With a Wrist Photoplethysmographic Device During Running

2017

BackgroundWearable sensors enable long-term monitoring of health and wellbeing indicators. An objective evaluation of sensors’ accuracy is important, especially for their use in health care. ObjectiveThe aim of this study was to use a wrist-worn optical heart rate (OHR) device to estimate heart rate (HR), energy expenditure (EE), and maximal oxygen intake capacity (VO2Max) during running and to evaluate the accuracy of the estimated parameters (HR, EE, and VO2Max) against golden reference methods. MethodsA total of 24 healthy volunteers, of whom 11 were female, with a mean age of 36.2 years (SD 8.2 years) participated in a submaximal self-paced outdoor running test and maximal voluntary exe…

medicine.medical_specialty020205 medical informaticsheart rate determinationexercise testHealth InformaticsInformation technology02 engineering and technology03 medical and health sciences0302 clinical medicinePhotoplethysmogramenergy metabolismStatisticsHeart rateheart rate0202 electrical engineering electronic engineering information engineeringmedicineOriginal Paperbusiness.industry030229 sport sciences217 Medical engineeringfitness trackersT58.5-58.64oxygen consumptionIntensity (physics)Mean absolute percentage errorEnergy expenditurePhysical performanceHeart Rate DeterminationPhysical therapyphotoplethysmographyObjective evaluationPublic aspects of medicineRA1-1270business
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Electrocardiographic Indices of Left Ventricular Hypertrophy and Repolarization Phase Share the Same Genetic Influences: A Twin Study

2009

Background: Both left ventricular hypertrophy (LVH) and repolarization phase (RP) are known to be attributable to genetic influences, but less is known whether they share same genetic influences. The aim of this study was to investigate to what extent individual differences in electrocardiographic (ECG) LVH and RP are explained by genetic and environmental influences and whether these influences are shared between these two traits. Methods: Resting ECG recordings were obtained from 186 monozygotic and 203 dizygotic female twin individuals, aged 63 to 76 years. Latent factors, called LVH and RP, were formed to condense the information obtained from LVH indices (Cornell voltage and Cornell pr…

medicine.medical_specialty030204 cardiovascular system & hematologyLeft ventricular hypertrophyGenetic correlationCorrelationElectrocardiography03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineGenetic modelingHumansRepolarizationMedicineGenetic Predisposition to Diseasecardiovascular diseases030212 general & internal medicineAgedbusiness.industryOriginal ArticlesGeneral MedicineMiddle AgedHeritabilitymedicine.diseaseTwin studyEndocrinologyCardiologyFemaleHypertrophy Left VentricularCardiology and Cardiovascular MedicinebusinessAnnals of Noninvasive Electrocardiology
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EEG Effective Source Projections Are More Bilaterally Symmetric in Infants Than in Adults

2020

Although anatomical brain hemispheric asymmetries have been clearly documented in the infant brain, findings concerning functional hemispheric specialization have been inconsistent. The present report aims to assess whether bilaterally symmetric synchronous activity between the two hemispheres is a characteristic of the infant brain. To asses cortical bilateral synchronicity, we used decomposition by independent component analysis (ICA) of high-density electroencephalographic (EEG) data collected in an auditory passive oddball paradigm. Decompositions of concatenated 64-channel EEG data epochs from each of 34 typically developing 6-month-old infants and from 18 healthy young adults particip…

medicine.medical_specialty1.1 Normal biological development and functioningAuditory oddballAudiologyElectroencephalography050105 experimental psychologylcsh:RC321-57103 medical and health sciencesFunctional brainBehavioral Neuroscience0302 clinical medicineClinical ResearchUnderpinning researchmedicinePsychology0501 psychology and cognitive sciencesEEGbrain symmetryOddball paradigmdevelopmentlcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological PsychiatryOriginal ResearchPediatricmedicine.diagnostic_testbusiness.industrybrain laterality05 social sciencesBrain maturationCortical fieldNeurosciencesExperimental Psychologyfunctional brain organizationIndependent component analysisPsychiatry and Mental healthmedicine.anatomical_structureNeuropsychology and Physiological PsychologyNeurologyindependent component analysisScalpNeurologicalCognitive Sciencesbusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Human Neuroscience
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Prevalence estimation of celiac disease in the general adult population of Latvia using serology and HLA genotyping

2015

Background: Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in epidemiological studies and diagnostic settings of celiac disease (CD) has still to be established. Objectives: The objective of this article is to assess the prevalence of CD in Latvia by combining serological tests with DQ2.5/ DQ8 testing. Methods: A total of 1444 adults from a randomly selected cross-sectional general population sample were tested by ELISA for tTG IgA, DGP IgA and IgG antibodies (QUANTA Lite, Inova Diagnostics Inc). Samples with tTG IgA 20U were tested for EMA IgA by indirect immunofluorescence assay, and all specimens wi…

medicine.medical_specialty:MEDICINE [Research Subject Categories]Tissue transglutaminasePopulationSerologyChemiluminescent assaysEpidemiologyGenotypePrevalenceCeliac diseaseMedicineDQ2.5/8 genotypeeducationGenotypingGenetic testingeducation.field_of_studyDeamidated gliadin peptidemedicine.diagnostic_testbiologybusiness.industryTissue transglutaminaseGastroenterologynutritional and metabolic diseasesOriginal ArticlesOncologyImmunologybiology.proteinAntibodybusinessUnited European Gastroenterology Journal
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The Effects of Intensive Weight Reduction on Body Composition and Serum Hormones in Female Fitness Competitors.

2017

Worries about the potential negative consequences of popular fat loss regimens for aesthetic purposes in normal weight females have been surfacing in the media. However, longitudinal studies investigating these kinds of diets are lacking. The purpose of the present study was to investigate the effects of a 4-month fat-loss diet in normal weight females competing in fitness-sport. In total 50 participants finished the study with 27 females (27.2 +/- 4.1 years) dieting for a competition and 23 (27.7 +/- 3.7 years) acting as weight-stable controls. The energy deficit of the diet group was achieved by reducing carbohydrate intake and increasing aerobic exercise while maintaining a high level of…

medicine.medical_specialtyANOREXIA-NERVOSAINCREASED PROTEIN-INTAKEENERGY DEFICITVastus lateralis musclePhysiologyAdipose tissueRESEARCH WORKING GROUP030209 endocrinology & metabolismBiologysex hormonesravinto03 medical and health sciences0302 clinical medicineWeight lossPhysiology (medical)Internal medicinemedicineBODYBUILDING CONTEST PREPARATIONAerobic exerciseTestosteronefat losskehonkoostumusOriginal Researchthyroid hormonessukupuolihormonitbody compositionexerciseLeptinLEAN MASS GAIN1184 Genetics developmental biology physiologyDIETARY-PROTEINta3141030229 sport sciencesIOC MEDICAL COMMISSIONfitnessEndocrinologyADIPOSE-TISSUEnutritionLean body mass3111 Biomedicinemedicine.symptomMETABOLIC ADAPTATIONDietingFrontiers in physiology
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Impact of switching from mycophenolate mofetil to enteric-coated mycophenolate sodium on gastrointestinal side effects in patients with autoimmune di…

2015

Bernhard Manger,1 Falk Hiepe,2 Matthias Schneider,3 Margitta Worm,4 Peter Wimmer,5 Eva-Maria Paulus,5 Andreas Schwarting6 1University Hospital Erlangen, Med Clinic III Polyclinic, Erlangen, 2Rheumatology, University Hospital Charité, Campus Mitte, Berlin, 3Policlinic of Rheumatology, Heinrich-Heine-Universität, Düsseldorf, 4Department of Dermatology, Venereology and Allergology, University Hospital Charité, Campus Mitte, Berlin, 5Novartis Pharma GmbH, Nürnberg, 6Department of Internal Medicine, Johannes Gutenberg University, Mainz, Germany Background: The purpose of this study was to assess changes in gastrointestinal symptom severity in pati…

medicine.medical_specialtyAbdominal painClinical and Experimental GastroenterologyNauseabusiness.industrymycophenolate mofetilGastroenterologyautoimmune diseaseenteric-coated mycophenolate sodiumpatient-reported outcomeIndigestionhealth-related quality of lifeQuality of lifeRating scaleInternal medicineClinical endpointmedicinePatient-reported outcomemedicine.symptomAdverse effectbusinessOriginal ResearchClinical and Experimental Gastroenterology
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General quality of life of patients with acne vulgaris before and after performing selected cosmetological treatments

2017

Background Achieving a satisfying quality of life for a patient by applying individually matched therapy is, simultaneously, a great challenge and a priority for contemporary medicine. Patients with visible dermatological ailments are particularly susceptible to reduction in the general quality of life. Among the dermatological diseases, acne causes considerable reduction in the quality of life and changes in self-perception that lead to the worsening of a patient's mental condition, including depression and suicidal thoughts. As a result, difficulties in contact with loved ones, as well as social and professional problems are observed, which show that acne is not a somatic problem alone. T…

medicine.medical_specialtyActivities of daily livingAlternative medicineMedicine (miscellaneous)cosmetological treatments030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineQuality of lifeacne vulgarisMedicine030212 general & internal medicinePharmacology Toxicology and Pharmaceutics (miscellaneous)AcneDepression (differential diagnoses)Original Researchbusiness.industryHealth PolicyDermatology Life Quality IndexPsychodermatologymedicine.diseaseDermatologyMesotherapyquality of lifebusinessSocial Sciences (miscellaneous)Patient Preference and Adherence
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Quantifying an Upper Extremity Everyday Task With 3D Kinematic Analysis in People With Spinal Cord Injury and Non-disabled Controls

2021

Objectives: Upper extremity function after spinal cord injury (SCI) is an important factor for performance of activities of daily living. An objective assessment of upper extremity function preferably in purposeful daily tasks is essential in understanding its impact on real-life activities. This study aimed to identify which movement parameters of upper extremity, measured by kinematic analysis during a purposeful daily task, are impaired in people with cervical or thoracic SCI.Materials and Methods: The study included 29 adults (mean 59.5 years, 9 women and 20 men) with cervical (n = 19) or thoracic (n = 10) established complete (n = 15) or incomplete (n = 14) SCI, and 54 non-disabled con…

medicine.medical_specialtyActivities of daily livingassessmentElbowPopulationKinematicsmovement analysisWristfunctioningPhysical medicine and rehabilitationMedicinequality of movementRC346-429upper extremity (arm)educationSpinal cord injuryOriginal Researcheducation.field_of_studybusiness.industrymedicine.diseaseDisplacement (psychology)Trunkspinal cord injurymedicine.anatomical_structureNeurologykinematicsdrinking taskNeurology. Diseases of the nervous systemNeurology (clinical)businessFrontiers in Neurology
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Medication adherence and persistence in type 2 diabetes mellitus: perspectives of patients, physicians and pharmacists on the Spanish health care sys…

2017

Elena Labrador Barba,1 Marta Rodríguez de Miguel,1 Antonio Hernández-Mijares,2,3 Francisco Javier Alonso-Moreno,4 Maria Luisa Orera Peña,1 Susana Aceituno,5 María José Faus Dader6 1Department of Medicine, Mylan, Madrid, 2Department of Endocrinology and Nutrition, Doctor Peset University Hospital, Valencia, 3Department of Medicine, University of Valencia, Valencia, 4Department for Primary Health Care, Centro de Salud Sillería, Toledo, 5Outcomes’10, Castellon, 6Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Granada, Granada, Spain Objective: A good relationship between diabetes pa…

medicine.medical_specialtyActivities of daily livingtype 2 diabetes mellitusMedicine (miscellaneous)030209 endocrinology & metabolismLikert scale03 medical and health sciences0302 clinical medicineDiabetes mellitusHealth caremedicine030212 general & internal medicineadherenceAdverse effectPharmacology Toxicology and Pharmaceutics (miscellaneous)Original Researchbusiness.industryHealth PolicyfactorsType 2 Diabetes Mellituspersistencemedicine.diseaseClinical pharmacyPatient Preference and AdherenceFamily medicinestrategiesObservational studybusinessSocial Sciences (miscellaneous)Patient preference and adherence
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The Association Between Quantitative Flow Ratio and Intravascular Imaging-defined Vulnerable Plaque Characteristics in Patients With Stable Angina an…

2021

Background: This study aimed to examine whether quantitative flow ratio (QFR), an angiography-based computation of fractional flow reserve, was associated with intravascular imaging-defined vulnerable plaque features, such as thin cap fibroatheroma (TCFA) in patients with stable angina, and non-ST-segment elevation acute coronary syndrome.Methods: Patients undergoing optical coherence tomography (OCT) or intravascular ultrasound (IVUS) examinations were identified from two prospective studies and their interrogated vessels were assessed with QFR. Lesions in the OCT cohort were classified into tertiles: QFR-T1 (QFR ≤ 0.85), QFR-T2 (0.85 < QFR ≤ 0.93), and QFR-T3 (QFR > 0.93). L…

medicine.medical_specialtyAcute coronary syndromeLumen (anatomy)Fractional flow reserveCardiovascular Medicine030204 cardiovascular system & hematologymedicine.disease_causequantitative flow ratio (QFR)03 medical and health sciences0302 clinical medicineInternal medicinefractional flow reserve (FFR)Intravascular ultrasoundmedicineDiseases of the circulatory (Cardiovascular) systemoptical coherence tomography (OCT)030212 general & internal medicineProspective cohort studyOriginal Researchintravascular ultrasound (IVUS)medicine.diagnostic_testbusiness.industryFibrous capmedicine.diseaseVulnerable plaquemedicine.anatomical_structureRC666-701AngiographyCardiologyplaque vulnerabilityCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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