Search results for "osteopenia"

showing 10 items of 30 documents

Significant liver fibrosis assessed using liver transient elastography is independently associated with low bone mineral density in patients with non…

2017

Background Metabolic bone disorders frequently occur in patients with chronic liver disease; however, the association between liver fibrosis and bone mineral density in patients with non-alcoholic fatty liver disease (NAFLD) is unclear. Methods This is a cross-sectional analysis of 231 asymptomatic subjects (160 women, 61.6 years old) from a university hospital setting, between February 2012 and December 2014. Bone mineral density (BMD) was measured at the lumbar spine, femur neck, and total hip using dual-energy X-ray absorptiometry (DXA). Liver fibrosis and steatosis were assessed using transient elastography. Results Among a total of 231 individuals, 129 subjects (55.8%) had NAFLD. BMDs …

Liver CirrhosisMalePathologySteatosisBone densityOsteoporosislcsh:MedicineChronic liver diseasePathology and Laboratory MedicineGastroenterologyBiochemistryCytopathology0302 clinical medicineFibrosisBone DensityNon-alcoholic Fatty Liver DiseaseMedicine and Health SciencesFemurlcsh:ScienceMusculoskeletal SystemBone mineralMultidisciplinaryLumbar VertebraeLiver DiseasesFatty liverMiddle AgedLipidsCholesterolConnective TissueLiver FibrosisElasticity Imaging Techniques030211 gastroenterology & hepatologyFemaleAnatomyResearch Articlemusculoskeletal diseasesmedicine.medical_specialty030209 endocrinology & metabolismGastroenterology and HepatologyPelvis03 medical and health sciencesInternal medicinemedicineHumansBoneSkeletonAgedHipbusiness.industrylcsh:RBiology and Life Sciencesmedicine.diseaseFibrosisOsteopeniaFatty LiverBone Diseases MetabolicBiological TissueAnatomical Pathologylcsh:QbusinessTransient elastographyDevelopmental BiologyPLoS ONE
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Muscle Activity and Inactivity Periods during Normal Daily Life

2013

Recent findings suggest that not only the lack of physical activity, but also prolonged times of sedentary behaviour where major locomotor muscles are inactive, significantly increase the risk of chronic diseases. The purpose of this study was to provide details of quadriceps and hamstring muscle inactivity and activity during normal daily life of ordinary people. Eighty-four volunteers (44 females, 40 males, 44.1±17.3 years, 172.3±6.1 cm, 70.1±10.2 kg) were measured during normal daily life using shorts measuring muscle electromyographic (EMG) activity (recording time 11.3±2.0 hours). EMG was normalized to isometric MVC (EMGMVC) during knee flexion and extension, and inactivity threshold o…

MaleActivities of daily livingAnatomy and PhysiologyTime FactorsOsteopenia and OsteoporosisIsometric exerciseElectromyographyCardiovascular SystemQuadriceps Muscletextile electrodes0302 clinical medicineActivities of Daily LivingBiomechanics030212 general & internal medicineMuscle activityta315Musculoskeletal Systeminactivelihasten aktiivisuusMultidisciplinarymedicine.diagnostic_testStair climbingQRMiddle AgedOccupational and Industrial Healthmusculoskeletal systemelektromyografiaMuscleMedicineFemalePublic Healthfyysinen aktiivisuusResearch ArticleinaktiivisuusAdultmedicine.medical_specialtySciencePhysical activitySittingNeurological System03 medical and health sciencesYoung AdultPhysical medicine and rehabilitationsedentarymedicineHumansSports and Exercise MedicineMuscle SkeletalAgedMotor Systemsbusiness.industryElectromyographyphysically active030229 sport sciencesbody regionsWomen's HealthExertionPreventive Medicinebusinesshuman activitiesHamstring
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The associations of serum serotonin with bone traits are age- and gender-specific

2014

Context Serotonin plays a potential role in bone metabolism, but the nature and extent of this relationship is unclear and human studies directly addressing the skeletal effect of circulating serotonin are rare. Objective The study aimed to investigate the associations between serum serotonin and bone traits at multiple skeletal sites in women and men. Subjects and Methods Subjects were part of the CALEX-family study and comprised 235 young women, 121 premenopausal women, 124 postmenopausal women, and 168 men. Body composition was assessed using DXA, as was areal bone mineral density (aBMD) of spine, femur and whole body. In addition, pQCT was used to determine bone properties at tibial mid…

MaleBone densityPhysiologyOsteopenia and Osteoporosislcsh:MedicineBioinformaticsBiochemistryBone remodelingCell SignalingEndocrine SignalingBone DensitySex factorsMedicine and Health SciencesFemurlcsh:Science10. No inequalityta315Aged 80 and overLumbar VertebraeMultidisciplinaryHuman studiesAge FactorsNeurochemistryta3141Middle AgedPostmenopauseBody CompositionOsteocalcinFemaleResearch ArticleSignal TransductionAdultmusculoskeletal diseasesSerotoninmedicine.medical_specialtyContext (language use)BiologyAge and genderSex FactorsInternal medicinemedicineHumansAgedEndocrine Physiologylcsh:RBiology and Life SciencesNeuroendocrinologyCell BiologyRadiographyEndocrinologybiology.proteinWomen's Healthlcsh:QEndocrine-Related SubstancesSerotoninPLOS ONE
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Drug‐refractory myasthenia gravis: Clinical characteristics, treatments, and outcome

2022

[Objective] To describe the clinical characteristics and outcomes in patients with refractory myasthenia gravis (MG) and to determine the effectiveness and side effects of the drugs used for their treatment.

Maleprogressive multifocal leukoencepdiarrheacholinergic receptorplasma exchangemiddle agedadultimmunologic factornauseaanemiahypertrichosisageddrug withdrawaldiabetes mellitusdisease severityTRIALsafetycorticosteroidhypertensionImmunologyMiastenia gravismethotrexateArticlebulbar paralysispancytopeniaMuscular DiseasescompulsionMyasthenia Gravischolinesterase inhibitorcross-sectional studyHumansImmunologic FactorshumanRITUXIMABarthralgiaNeurologíaMalalties muscularsAgedRetrospective Studiesmyasthenia gravisleukopeniaabdominal painDrug testingmajor clinical studyCross-Sectional StudiesDrug side effectscyclophosphamideobservational studyNeurology (clinical)immunoglobulinFEATURESefficacyclinical outcomeelectrophysiological procedurescomputer assisted tomographyDOUBLE-BLINDTratamiento médicorituximabOutcome Assessment Health CareImmunologiamuscle specific tyrosine kinaseRegistriestacrolimusazathioprineMedicamentoGeneral Neurosciencenephrotoxicitygeneral condition deteriorationhyperplasiatrialMiddle Agedliver toxicitydrug toxicityunclassified drugfemaleEfectes secundaris dels medicamentsSAFETYFemaledouble-blindheadacheblindnessAdultAssaigs clínics de medicamentsmalefeaturesfollow uppneumoniacyclosporinemycophenolate mofetilprotein tyrosine kinaseimmunosuppressive agentallergyalopeciaEFFICACYclinical featureosteopeniaSpainprednisonehyperglycemiaautoantibodyFollow-Up Studies
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Postmenopausal women with osteopenia and a healed wrist fracture have reduced physical function and quality of life compared to a matched, healthy co…

2014

Background: Fractures lead to reduced physical function and quality of life (QOL), but little is known about postmenopausal women with osteopenia and a healed wrist fracture. The purpose was to evaluate physical function in terms of quadriceps strength, dynamic balance, physical capacity and QOL in postmenopausal women with osteopenia and a healed wrist fracture compared to a matched, healthy control group with no previous fracture. Methods: Eighteen postmenopausal women with osteopenia (patients) (mean age 59.1 years, range 54 – 65) and a healed wrist fracture were matched to 18 healthy control subjects on age (mean age 58.5 years, range 51 – 65), height, weight and body mass index (BMI). …

Medicine(all)osteopeniaquadriceps strengthwrist fractureObstetrics and Gynaecologydynamic balancepostmenopausal womenBMC Women's Health
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Postmenopausal women with osteopenia and a healed wrist fracture have reduced physical function and quality of life compared to a matched, healthy co…

2013

Background Fractures lead to reduced physical function and quality of life (QOL), but little is known about postmenopausal women with osteopenia and a healed wrist fracture. The purpose was to evaluate physical function in terms of quadriceps strength, dynamic balance, physical capacity and QOL in postmenopausal women with osteopenia and a healed wrist fracture compared to a matched, healthy control group with no previous fracture. Methods Eighteen postmenopausal women with osteopenia (patients) (mean age 59.1 years, range 54 – 65) and a healed wrist fracture were matched to 18 healthy control subjects on age (mean age 58.5 years, range 51 – 65), height, weight and body mass index (BMI). We…

OsteopeniaMiddle AgedMotor ActivityWrist InjuriesPostmenopausal womenQuadriceps MuscleQuadriceps strengthPostmenopauseBone Diseases MetabolicFractures BoneAbsorptiometry PhotonBone DensityCase-Control StudiesExercise TestQuality of LifeHumansFemaleMuscle StrengthWrist fracturePostural BalanceAgedResearch ArticleDynamic balanceBMC women's health
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Prevalence of densitometric osteoporosis and osteopenia in Spain

2011

Osteopeniamedicine.medical_specialtyPediatricsHistologyPhysiologybusiness.industryEndocrinology Diabetes and MetabolismEpidemiologyOsteoporosismedicinebusinessDensitometrymedicine.disease
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Bone mineral metabolism in the micropremie

2000

Environmental factors, nutritional supplies, hormonal status, diseases, and treatments appear to affect postnatal skeletal growth and mineralization in VLBW infants. Compared with their term counterparts, ELBW infants are at risk of postnatal growth deficiency and osteopenia at the time of hospital discharge. From recent data, DXA is becoming one of the reference techniques to evaluate mineral status, whole-body composition, and effects of dietary manipulations on weight gain composition and mineral accretion in preterm infants. Weight gain and length increases need to be evaluated carefully during the first weeks of life, in the intensive care unit and out of it, in the step down unit. Nut…

Peak bone massParenteral NutritionPediatricsmedicine.medical_specialtyBone mineral metabolismWeight Gainlaw.inventionCalcification PhysiologicEnteral NutritionlawInternal medicinemedicineHumansInfant Very Low Birth WeightInfant Nutritional Physiological PhenomenaInfant Nutritional Physiological PhenomenaMineralsBone Developmentbusiness.industryInfant NewbornObstetrics and Gynecologymedicine.diseaseIntensive care unitOsteopeniaEndocrinologyParenteral nutritionPediatrics Perinatology and Child Healthmedicine.symptomLinear growthbusinessWeight gainInfant Premature
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Effect of exercises with weight vests and a patient education programme for women with osteopenia and a healed wrist fracture: a randomized, controll…

2015

Background Exercise programmes have shown to be important for the prevention of fractures in patients with established osteoporosis. However, few studies have evaluated the effect of such programmes for women with low bone mineral density (BMD) (osteoporosis or osteopenia) who have already suffered a fracture. Studies have indicated that exercise programmes concentrating on muscular strength and dynamic balance have a positive effect on significant risk factors for falls such as quadriceps strength and balance. The aim of the present study was to assess the effect of a 6-month exercise programme and a patient education component (OsteoACTIVE) on quadriceps strength, BMD, dynamic balance, wa…

Wrist Jointmedicine.medical_specialtySports medicinemedicine.medical_treatmentOsteoporosisPhysical strengthlaw.inventionQuadriceps strengthPhysical medicine and rehabilitationRheumatologyQuality of lifeRandomized controlled trialPatient Education as TopiclawmedicineHumansOrthopedics and Sports MedicineSingle-Blind MethodMuscle StrengthExerciseAgedAged 80 and overRehabilitationbusiness.industryOsteopeniaRehabilitationWeight vestResistance TrainingMiddle Agedmedicine.diseasePhysical activity levelExercise TherapyOsteopeniaBone Diseases MetabolicTreatment OutcomePhysical therapyFemalebusinessRadius FracturesResearch ArticleFollow-Up StudiesBMC Musculoskeletal Disorders
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Progressive femoral cortical and cancellous bone density loss after uncemented tapered-design stem fixation

2010

Background Aseptic implant loosening and periprosthetic bone loss are major problems after total hip arthroplasty (THA). We present an in vivo method of computed tomography (CT) assisted osteodensitometry after THA that differentiates between cortical and cancellous bone density (BD) and area around the femoral component.Method Cortical and cancellous periprosthetic femoral BD (mg CaHA/mL), area (mm2) and contact area between the prothesis and cortical bone were determined prospectively in 31 patients 10 days, 1 year, and 6 years after uncemented THA (mean age at implantation: 55 years) using CT-osteodensitometry.Results 6 years postoperatively, cancellous BD had decreased by as much as 41%…

business.industryPeriprostheticGeneral MedicineAnatomymedicine.diseaseOsteopeniaDiaphysismedicine.anatomical_structuremedicineOrthopedics and Sports MedicineSurgeryCortical boneFemurImplantbusinessCancellous boneFixation (histology)Acta Orthopaedica
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