Search results for "otc"

‘Acting-out’ dynamics : Can physical manipulation foster building of mental models from animation?

2016

International audience; The effects of (i) learner demonstration (using a manipulable model) and (ii) writing for understanding on learning from an animation of a Scotch Yoke mechanism were compared in a time-controlled investigation. Post-tests assessed the quality of the Scotch Yoke mental model acquired in the two learning conditions. On the basis of the Animation Processing Model (Lowe & Boucheix, 2008), we hypothesized that participants in the demonstration condition should outperform those in the writing condition because having to demonstrate the behaviors of the Scotch Yoke would result in deeper processing of crucial dynamic information in the animation. Results of the investigatio…

Re-analysis of fatigue data for welded joints using the notch stress approach

2010

Abstract Experimental fatigue data for welded joints have been collected and subjected to re-analysis using the notch stress approach according to IIW recommendations. This leads to an overview regarding the reliability of the approach, based on a large number of results (767 specimens). Evidently, there are some limitations in the approach regarding mild notch joints, such as butt joints, which can be assessed non-conservatively. In order to alleviate this problem, an increased minimum notch factor of Kw ⩾ 2.0 is suggested instead of the current recommendation of Kw ⩾ 1.6. The data for most fillet-welded joints agree quite well with the FAT 225 curve; however a reduction to FAT 200 is sugg…

Fauna Europaea: Hymenoptera - Apocrita (excl. Ichneumonoidea)

2015

Fauna Europaea provides a public web-service with an index of scientific names (including important synonyms) of all living European land and freshwater animals, their geographical distribution at country level (up to the Urals, excluding the Caucasus region), and some additional information. The Fauna Europaea project covers about 230,000 taxonomic names, including 130,000 accepted species and 14,000 accepted subspecies. This represents a huge effort by more than 400 contributing specialists throughout Europe and is a unique (standard) reference suitable for many users in science, government, industry, nature conservation and education. Hymenoptera is one of the four largest orders of inse…

Tool Wear and Damage

2008

This chapter provides comprehensive knowledge regarding tool wear mechanisms and characterizes their physical fundamentals. Adhesion, abrasion, diffusion and oxidation are selected as predominant mechanisms controlling tool wear, depending on the mechanical and thermal conditions at the rake and flank faces. The analytical models describing the wear rate and volumetric material loss for different wear mechanisms are provided. The tool wear indicators related to crater, flank and notch wear specified in ISO 3685 are presented for both flat-faced and grooved tools. Tool life is defined and corresponding models, including the influence of cutting speed, feed and the depth of cut, are derived. …

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dl…

2013

Background In-situ hybridisation studies demonstrate that Notch receptors and ligands are expressed in granulosa cells (GCs) and in the theca layer vasculature of growing follicles. Notch signaling involves cell-to-cell interaction mediated by transmembrane receptors and ligands. This signaling pathway may represent a novel intraovarian regulator of gonadotropin-dependent follicular development to the preovulatory stage. We hypothesized that blocking Notch pathways would disrupt follicular maturation in the mouse ovary. Methods Hypophysectomized CD21 female mice were administered pregnant mare serum gonadotropin (PMSG) for 3 days to stimulate follicular development. In one experiment, a pan…

Modelling, Identification and Control of a 5-DOF Shotcrete Robot : Development of a Framework for Automatic Application of Shotcrete for AMV 4200H

2019

Master's thesis Mechatronics MAS500 - University of Agder 2019 Today, process automation is the primary area of development in the shotcrete industry. Automaticshotcrete operations can yield an increase in operational efficiency and personnel safety as well asreductions in cost and environmental impact. This thesis develops a framework for automaticapplication of shotcrete using the AMV 4200H and provides an automatic spraying mode usinginteroceptive sensing. The shotcrete vehicle is equipped with a five degrees-of-freedom manipulatorand is currently operated manually. Our contributions include solving the forward kinematicsthrough the Denavit-Hartenberg convention, and the inverse kinemati…

Zemes un vides zinātnes

2011

A central role for Notch in effector CD8(+) T cell differentiation.

2014

Activated CD8(+) T cells choose between terminal effector cell (TEC) or memory precursor cell (MPC) fates. We found that the signaling receptor Notch controls this 'choice'. Notch promoted the differentiation of immediately protective TECs and was correspondingly required for the clearance of acute infection with influenza virus. Notch activated a major portion of the TEC-specific gene-expression program and suppressed the MPC-specific program. Expression of Notch was induced on naive CD8(+) T cells by inflammatory mediators and interleukin 2 (IL-2) via pathways dependent on the metabolic checkpoint kinase mTOR and the transcription factor T-bet. These pathways were subsequently amplified d…

Low Density Lipoprotein Receptor-related Protein (LRP) Interacts with Presenilin 1 and Is a Competitive Substrate of the Amyloid Precursor Protein (A…

2005

Presenilin 1 (PS1) is a critical component of the gamma-secretase complex, which is involved in the cleavage of several substrates including the amyloid precursor protein (APP) and the Notch receptor. Recently, the low density receptor-related protein (LRP) has been shown to be cleaved by a gamma-secretase-like activity. We postulated that LRP may interact with PS1 and tested its role as a competitive substrate for gamma-secretase. In this report we show that LRP colocalizes and interacts with endogenous PS1 using coimmunoprecipitation and fluorescence lifetime imaging microscopy. In addition, we found that gamma-secretase active site inhibitors do not disrupt the interaction between LRP an…

Dinotrema cavernicola sp. n. (Hymenoptera, Braconidae, Alysiinae), a new species of the genus Dinotrema Foerster from caves of Spain

2014

Dinotrema cavernicola sp. n. was collected in two caves in Spain. This is the first Dinotrema species known to occur in caves. This new species is described and compared to D. affine (Fischer, 1973) and D. collybiae Munk & Peris-Felipo, 2014, species sharing a mid-longitudinal carina on the propodeum.