Search results for "outer"

showing 2 items of 252 documents

Production of Norspermidine Contributes to Aminoglycoside Resistance in pmrAB Mutants of Pseudomonas aeruginosa

2019

Emergence of resistance to polymyxins in Pseudomonas aeruginosa is mainly due to mutations in two-components systems, that promote addition of 4-amino-4-deoxy-L-arabinose to the lipopolysaccharide (LPS) through upregulation of operon arnBCADTEF-ugd (arn) expression. Here, we demonstrate that mutations occurring in different domains of histidine kinase PmrB or in response regulator PmrA result in coresistance to aminoglycosides and colistin. All seventeen clinical strains tested exhibiting such a cross-resistance phenotype were found to be pmrAB mutants. As shown by gene deletion experiments, the decreased susceptibility of the mutants to aminoglycosides was independent from operon arn but r…

Spectrometry Mass Electrospray IonizationOperonSpermidineMutantMicrobial Sensitivity TestsMicrobiology03 medical and health scienceschemistry.chemical_compoundBacterial ProteinsMechanisms of Resistance[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]PolyaminesPharmacology (medical)GeneComputingMilieux_MISCELLANEOUS030304 developmental biologyPharmacology0303 health sciences030306 microbiologyColistinNorspermidineHistidine kinaseGene Expression Regulation Bacterial[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyAnti-Bacterial AgentsResponse regulatorInfectious DiseasesAminoglycosideschemistryPseudomonas aeruginosaEffluxBacterial outer membraneTranscription Factors
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PIL.21-22-Unit 10. State competences over other areas of international interest

2022

Public International Law. Unit 10. State competences over other areas of international interest. Powerpoint of the Academic course 2021-2022. 1. International waterways. 2. The polar spaces. (a) The Arctic region. (b) The Antarctic Region. i. General ideas. ii. Legal regime. iii. Applicable principles. 3. Outer space. (a) General ideas. (b) Legal regime. i. Legal status of outer space. ii. Legal regime for the exploration and use of outer space. iii. Legal regime for space objects. iv. Legal status of astronauts.

public international lawAntarcticaUNESCO::CIENCIAS JURÍDICAS Y DERECHOouterspaceartic
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