Search results for "outliers"
showing 10 items of 14 documents
TERMITE: AnRscript for fast reduction of laser ablation inductively coupled plasma mass spectrometry data and its application to trace element measur…
2017
RATIONALE High spatial resolution Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICPMS) determination of trace element concentrations is of great interest for geological and environmental studies. Data reduction is a very important aspect of LA-ICP-MS, and several commercial programs for handling LA-ICPMS trace element data are available. Each of these software packages has its specific advantages and disadvantages. METHODS Here we present TERMITE, an R script for the reduction of LA-ICPMS data, which can reduce both spot and line scan measurements. Several parameters can be adjusted by the user, who does not necessarily need prior knowledge in R. Currently, ten reference m…
Influence Diagnostics for Meta-Analysis of Individual Patient Data Using Generalized Linear Mixed Models
2014
In meta-analysis, generalized linear mixed models (GLMMs) are usually used when heterogeneity is present and individual patient data (IPD) are available, while accepting binary, discrete as well as continuous response variables. In the present paper some measures of influence diagnostics based on log-likelihood are suggested and discussed. A known measure is approximated to get a simpler form, for which the information matrix is no more necessary. The performance of the proposed measure is assessed through a diagnostic analysis on simulated data reproducing a possible meta-analytical context of IPD with influential outliers. The proposed measure is showed to work well and to have a form sim…
Reputation or peer review? The role of outliers
2018
We present an agent-based model of paper publication and consumption that allows to study the effect of two different evaluation mechanisms, peer review and reputation, on the quality of the manuscripts accessed by a scientific community. The model was empirically calibrated on two data sets, mono- and multi-disciplinary. Our results point out that disciplinary settings differ in the rapidity with which they deal with extreme events—papers that have an extremely high quality, that we call outliers. In the mono-disciplinary case, reputation is better than traditional peer review to optimize the quality of papers read by researchers. In the multi-disciplinary case, if the quality landscape is…
Influence diagnostics for generalized linear mixed models: a gradient-like statistic
2013
In the literature, many influence measures proposed for Generalized Linear Mixed Models (GLMMs) require the information matrix that can be difficult to calculate. In the present paper, a known influence measure is approximated to get a simpler form, for which the information matrix is no more necessary. The proposed measure is showed to have a form similar to the gradient statistic, recently introduced. Good performances have been obtained through simulation studies.
RAD SNP markers as a tool for conservation of dolphinfish Coryphaena hippurus in the Mediterranean Sea: Identification of subtle genetic structure an…
2016
Dolphinfish is an important fish species for both commercial and sport fishing, but so far limited information is available on genetic variability and pattern of differentiation of dolphinfish populations in the Mediterranean basin. Recently developed techniques allow genome-wide identification of genetic markers for better understanding of population structure in species with limited genome information. Using restriction-site associated DNA analysis we successfully genotyped 140 individuals of dolphinfish from eight locations in the Mediterranean Sea at 3324 SNP loci. We identified 311 sex-related loci that were used to assess sex-ratio in dolphinfish populations. In addition, we identifie…
Comparison of Epithor clinical national database and medico-administrative database to identify the influence of case-mix on the estimation of hospit…
2019
BackgroundThe national Epithor database was initiated in 2003 in France. Fifteen years on, a quality assessment of the recorded data seemed necessary. This study examines the completeness of the data recorded in Epithor through a comparison with the French PMSI database, which is the national medico-administrative reference database. The aim of this study was to demonstrate the influence of data quality with respect to identifying 30-day mortality hospital outliers.MethodsWe used each hospital's individual FINESS code to compare the number of pulmonary resections and deaths recorded in Epithor to the figures found in the PMSI. Centers were classified into either the good-quality data (GQD) …
Diagnostics for meta-analysis based on generalized linear mixed models
2012
Meta-analysis is the method to combine data coming from multiple studies, with the aim to provide an overall event-risk measure of interest summarizing information coming from the studies. In meta-analysis generalized linear mixed models (GLMM) are particularly used for a number of measures of interest since they allow the true effect size to differ from study to study while accepting binary, discrete as well as continuous response variable. In the present paper some strategies of influence diagnostics based on log-likelihood are suggested and discussed. These are considered for Individual Patient Data, Aggregate Data and their compounding.
Outlier detection to hierarchical and mixed effects models
2008
Hierarchical and mixed effects models are models where a varying number of coefficients may be random at different levels of the hierarchy. The purpose of outlier analysis for these models is to determine whether an outlying unit at higher level is entirely outlying, or outlying due to effect of one or a few aberrant lower level units. Most works on diagnostics for these complex models have focused on the mixed model rather than on the hierarchical models, obscuring some relevant aspects of the hierarchical model. In this paper we will present an approach to influence analysis and outlier detection for mixed and hierarchical model, focusing on the special structure of nested data that these…
Geometric quality and appearance of surfaces : local and global approaches
2012
Accounting for customers' perception of manufactured goods has become a major challenge for the industry. This process is to be established from early design to retail. Customers are nowadays more aware and detail oriented about perceived quality of products. This allows one to set not only an estimated price but also the expected quality of the product. Surface appearance analysis has therefore become a key industrial issue. Two approaches are proposed here to formalize the detection methodology and provide objective criteria for experts to evaluate surface anomalies. The first proposed approach is based on surface metrology. It consists in analyzing the measured topologies in order to bin…