Search results for "ovine"

showing 10 items of 317 documents

Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-

2019

In the context of there being a limited number of clinically approved drugs for the treatment of Candida sp.-based infections, along with the rapid development of resistance to the existing antifungals, two novel series of 4-phenyl-1,3-thiazole and 2-hydrazinyl-4-phenyl-1,3-thiazole derivatives were synthesized and tested in vitro for their anti-Candida potential. Two compounds (7a and 7e) showed promising inhibitory activity against the pathogenic C. albicans strain, exhibiting substantially lower MIC values (7.81 μg/mL and 3.9 μg/mL, respectively) as compared with the reference drug fluconazole (15.62 μg/mL). Their anti-Candida activity is also supported by molecular docking studies, usin…

Molecular Docking Simulation13-thiazoleStructure-Activity RelationshipAntifungal Agentsbovine serum albuminfluorescence quenchingSerum Albumin Bovineanti-Candidamolecular dockingArticleCandidaMolecules (Basel, Switzerland)
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Hypothèse de Muséalisation en plein air pour le Quartier hellénistique-romain à Agrigente / Ipotesi di musealizzazione outdoor per il Quartiere ellen…

2014

The contribution presents the results of the activities carried out as a Expert in Museography for the APER project, which included the elaboration of a Musealisation hypothesis for the Domus IA-IB of the Hellenistic-Roman quarter located in Agrigento, i.e. the definition of intervention lines to be applied in an outdoor context to help the general public understand the archaeological site concerned to. The selected museographic strategies correspond to true forms of museal memorisation, aimed at knowing how to transmit the interpretation of an ancient context and its significance to a non-specialist public. In the conclusive phase, it has developed an executive project for two museographic…

Musealizzazione outdoor Siti archeologici Presentazione delle rovineSettore ICAR/16 - Architettura Degli Interni E Allestimento
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Muséaliser l’archéologie : quelques interventions innovantes pour la présentation des ruines / Musealizzare l’archeologia: alcuni interventi innovati…

2014

Intervention on archaeological sites requires a multicriteria approach, which does not lend itself to providing solutions of a general nature so much as solutions linked to the individual case at hand and to the comparison of the interventions involved in the creation of a museum-like context for them. Nevertheless, one should not lose sight of the general aspect of the problem and underestimate a series of considerations regarding what to conserve and why in favour of how to conserve, an aspect which has been extensively tested and which today offers a large range of appropriate solutions and techniques. It is a question of communication, solutions to which must be provided both through to…

Musealizzazione outdoor Siti archeologici Presentazione delle rovineSettore ICAR/16 - Architettura Degli Interni E Allestimento
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Study of ovine immune response against Mycoplasma agalactiae during natural and experimental infection and comparison of different vaccine formulatio…

2012

Mycoplasma agalactiaeSettore MED/04 - Patologia Generaleovinevaccineinfectionovine; Mycoplasma agalactiae; infection; vaccine;
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Structure and biological evaluation of amino-functionalized PVP nanogels for fast cellular internalization

2013

Abstract Aminopropyl methacrylamide chloride-graft-poly(N-vinyl pyrrolidone) nanogels (NGs) were designed to exploit the favorable properties of poly(N-vinyl pyrrolidone) (PVP), such as its high affinity to water and complexation ability of ions, molecules and macromolecules, with the availability of primary amino groups for bioconjugation reactions. A thorough structural characterization of the nanoscalar networks was performed via 1 H NMR and solid state 13 C NMR spectroscopies, while solid state NMR relaxation time measurements completed the NGs description in terms of polymer network density. Information on the hydrodynamic size and surface charge densities were sought via dynamic light…

Nanogels Poly(N-vinyl pyrrolidone) Microemulsion polymerization Proton spin–lattice relaxation time Cellular internalizationPolymers and PlasticsGeneral Chemical EngineeringNanogelsBiochemistrychemistry.chemical_compoundproton spin- lattice relaxation timeDynamic light scatteringmicroemulsion polymerizationPolymer chemistryMaterials ChemistryEnvironmental ChemistryMethacrylamideBovine serum albuminBioconjugationbiologyChemistryGeneral ChemistryCarbon-13 NMRCombinatorial chemistrypoly(N-vinyl pyrrolidone)biology.proteinProton NMRcellular internalizationSettore CHIM/07 - Fondamenti Chimici Delle TecnologieNanocarriersMacromolecule
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Evaluation of the healing of precoated vascular dacron prostheses.

1991

Knitted and woven Dacron grafts commercially coated with bovine collagen, gelatin and human albumin were implanted end-to-side between the infrarenal aorta and the bifurcation in 35 growing pigs. Grafts were explanted after 4, 8 and 12 weeks and compared to 6 uncoated knitted prostheses preclotted with blood that served as a control. Uncoated grafts rapidly developed a firmly attached neointima lined with endothelium. Compared with coated grafts the thrombus-free area of uncoated grafts was significantly larger (P less than 0.05). The slow resorption of albumin resulted in a delayed and incomplete neointimal healing and failing graft incorporation. Although the bovine collagen was only mini…

Neointimamedicine.medical_specialtyBovine collagenfood.ingredientEndotheliumSurface PropertiesSwineProsthesis DesignGelatinfoodmedicineAnimalsSerum AlbuminWound Healingbusiness.industryPolyethylene TerephthalatesAlbuminGraft Occlusion VascularCapsuleHyperplasiamedicine.diseaseSurgeryResorptionBlood Vessel ProsthesisProsthesis Failuremedicine.anatomical_structureMicroscopy Electron ScanningGelatinSurgeryFemaleCollagenEndothelium VascularbusinessBiomedical engineeringLangenbecks Archiv fur Chirurgie
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Phenylpropanoid and phenylisoprenoid metabolites from Asteraceae species as inhibitors of protein carbonylation.

2011

Abstract Three phenolic antioxidant and anti-inflammatory compounds: 7-methylaromadendrin, isoprenylhydroquinone glucoside, and 3.5-dicaffeoylquinic acid methyl ester, all isolated from Western Mediterranean Asteraceae species, have been studied for their inhibitory activity against protein carbonylation, a harmful post-translational modification of peptide chains associated with degenerative diseases. All compounds have proven to be effective, with 50% inhibitory concentration (IC 50 ) values in the micromolar range, against bovine serum albumin carbonylation caused by hypochlorite, peroxynitrite, and phorbol ester-induced leukocyte oxidative burst.

NeutrophilsProtein CarbonylationLeukocyte oxidative burstHypochloritePlant ScienceHorticultureAsteraceaeBiochemistryAntioxidantsProtein Carbonylationchemistry.chemical_compoundInhibitory Concentration 50GlucosideGlucosidesPhenolsPeroxynitrous AcidPhorbol EstersHumansBovine serum albuminMolecular BiologyRespiratory BurstFlavonoidsbiologyPhenylpropanoidCell-Free SystemSerum Albumin BovineGeneral MedicineHydroquinonesHypochlorous AcidchemistryBiochemistryFlavanonesbiology.proteinChlorogenic AcidCarbonylationProtein Processing Post-TranslationalPeroxynitritePhytochemistry
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Nitrogen and sulfur co-doped carbon nanodots toward bovine hemoglobin: A fluorescence quenching mechanism investigation

2018

A deep understanding of the molecular interactions of carbon nanodots with biomacromolecules is essential for wider applications of carbon nanodots both in vitro and in vivo. Herein, nitrogen and sulfur co-doped carbon dots (N,S-CDs) with a quantum yield of 16% were synthesized by a 1-step hydrothermal method. The N,S-CDs exhibited a good dispersion, with a graphite-like structure, along with the fluorescence lifetime of approximately 7.50 ns. Findings showed that the fluorescence of the N,S-CDs was effectively quenched by bovine hemoglobin as a result of the static fluorescence quenching. The mentioned quenching mechanism was investigated by the Stern-Volmer equation, temperature-dependent…

NitrogenQuantum yieldchemistry.chemical_element010402 general chemistryPhotochemistry01 natural sciencesHemoglobinsStructural BiologyQuantum DotsAnimalsMolecular Biologybovine hemoglobinQuenching (fluorescence)010401 analytical chemistryFluorescenceSulfurAcceptorNitrogenCarbon0104 chemical sciencesquenching mechanismchemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoCattlefluorescenceDispersion (chemistry)CarbonSulfurnitrogen and sulfur co-doped carbon dotsJournal of Molecular Recognition
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Simple liquid chromatography assay for analyzing ochratoxin a in bovine milk

2006

Ochratoxin Achemistry.chemical_compoundBovine milkChromatographyChemistryGeneral MedicineToxicologyToxicology Letters
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"Io son l'umile ancella del genio creator...". Percorsi di Francesco Cilea dal teatro verista ad "Adriana Lecouvreur"

2020

Il saggio delinea i percorsi biografici e artistici di Francesco Cilea, nel contesto della cultura italiana fra Otto e Novecento e con particolare riferimento alla fonte letteraria, alla genesi, ai personaggi, alla drammaturgia e al carattere musicale dell'opera in quattro atti "Adriana Lecouvreur" (1902).

Opera lirica verismo Giovine scuola Francesco Cilea Arturo Colautti Adriana LecouvreurSettore L-ART/07 - Musicologia E Storia Della Musica
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