Search results for "pair"

Quantitative EEG differentiates multiple sclerosis with and without cognitive impairment from healthy controls at the beginning of the disease: preli…

2018

Background and aims: The present study aims to assess possible qEEG differences between newly diagnosed multiple sclerosis (MS) patients with or without cognitive impairment (CI). Methods: We enrolled 22 patients (18-55-years-old) treated with first-line drugs for <6 months, and 11 healthy controls. All subjects underwent neuropsychological assessment including BICAMS and BDI. EEG recordings were performed during a cognitive task (computerised “SDMT” subtest of BICAMS) and at rest. Based on neuropsychological assessment, patients were considered as affected (MSCI group) or not (MS group) by cognitive impairment. We analysed data comparing MSCI patients matched by sex, age (±5years) and e…

Rappresentazioni tattili

2020

Sebbene molto spesso le persone con disabilità debbano accontentarsi di vivere parzialmente alcune esperienze, da diversi anni è aumentata l’attenzione dei siti museali verso la realizzazione di progetti e percorsi dedicati che consentano una fruizione tattile di opere e manufatti ai disabili visivi. Il contributo presenta due casi studio, che utilizzano modelli 3D per installazioni tattili. In presenza di deficit visivo, è importante rafforzare le facoltà percettive connettendo il tatto con i sensi residui e fornendo stimoli cognitivi diversi e paralleli. L’approccio multisensoriale, tattile e uditivo, realizzato grazie alla commistione tra modelli 3D e componenti elettroniche, favorisce l…

Anodal Transcranial Direct Current Stimulation Over Prefrontal Cortex Slows Sequence Learning in Older Adults

2022

Aging is associated with declines in sensorimotor function. Several studies have demonstrated that transcranial direct current stimulation (tDCS), a form of non-invasive brain stimulation, can be combined with training to mitigate age-related cognitive and motor declines. However, in some cases, the application of tDCS disrupts performance and learning. Here, we applied anodal tDCS either over the left prefrontal cortex (PFC), right PFC, supplementary motor complex (SMC), the left M1, or in a sham condition while older adults (n = 63) practiced a Discrete Sequence Production (DSP), an explicit motor sequence, task across 3 days. We hypothesized that stimulation to either the right or left P…

Human, Technologies and Quality of Education: Proceedings of Scientific Papers, 2020

2020

Clinical assessment and comparison of ACL reconstruction using synthetic graft (Neoligaments versus FiberTape).

2021

Background Due to the low potential for primary biological healing of the anterior cruciate ligament (ACL), the most popular approach is currently reconstruction using a graft. Recent research indicates that the technique of strengthening a damaged ligament with synthetic tapes (internal bracing) may be an alternative to reconstructive treatment, especially in cases of partial ACL damage. Objectives To compare and evaluate the possibility of using a synthetic graft (Neoligaments or FiberTape) to treat partial lesions of the ACL. Material and methods This was a retrospective cohort study. Selected from a pool of 128 patients undergoing primary unilateral intra-articular ACL reconstruction du…

In search of proper pronunciation : students’ practices of soliciting help during read-aloud

2017

In search of proper pronunciation : students’ practices of soliciting help during read-aloud

2017

Prioritization of Alternatives with AHP Plus Response Latency and Web Surveys

2013

Purpose: Overcome some drawbacks of the widely applied Analytical Hierarchy Process (AHP) related to the use of a rating scale for respondent’s judgments and propose a new method to prioritize alternatives based on web surveys. Methodology/Approach: We use the response latency, i.e. the time taken to make a decision, to replace the rating scale in the pairwise comparisons which is a fundamental part of the AHP procedure. A method combining the AHP with a mathematical model for the response latency is proposed in the paper. Findings: Eliminating the rating scale and leaving only the “take the best” task alleviates the respondent and makes the survey much faster and intuitive. Moreover the re…

Late Activation of Stress-activated Protein Kinases/c-Jun N-terminal Kinases Triggered by Cisplatin-induced DNA Damage in Repair-defective Cells

2011

Although stress-activated protein kinases/c-Jun N-terminal kinases (SAPK/JNK) are rapidly activated by genotoxins, the role of DNA damage in this response is not well defined. Here we show that the SEK1/MKK4-mediated dual phosphorylation of SAPK/JNK (Thr-183/Tyr-185) correlates with the level of cisplatin-DNA adducts at late times (16–24 h) after drug treatment in both human and mouse cells. Transfection of platinated plasmid DNA also caused SAPK/JNK activation. A defect in transcription-coupled nucleotide excision repair resting on a mutation in Cockayne syndrome group B protein promoted the late SAPK/JNK activation following cisplatin exposure. Signaling to SAPK/JNK was accompanied by act…

Positron production using a 9 MeV electron linac for the GBAR experiment

2020

For the GBAR (Gravitational Behaviour of Antihydrogen at Rest) experiment at CERN's Antiproton Decelerator (AD) facility we have constructed a source of slow positrons, which uses a low-energy electron linear accelerator (linac). The driver linac produces electrons of 9 MeV kinetic energy that create positrons from bremsstrahlung-induced pair production. Staying below 10 MeV ensures no persistent radioactive activation in the target zone and that the radiation level outside the biological shield is safe for public access. An annealed tungsten-mesh assembly placed directly behind the target acts as a positron moderator. The system produces $5\times10^7$ slow positrons per second, a performan…