Search results for "pan"

1-Aminocyclopropane-1-Carboxylic Acid, its Malonyl Conjugate and 1-Aminocyclopropane-1-Carboxylate Synthase Activity in Needles of Damaged and Undama…

1994

Summary Levels of free 1-aminocyclopropane-1-carboxylic acid (ACC), its malonyl conjugate (MACC) and ACC-synthase activity were significantly higher in the needles of damaged Norway spruce trees ( Picea abies (L.) Karst ) compared with those in undamaged trees during both the diurnal and seasonal courses. The concentrations of ACC and MACC, and ACC-synthase activity fluctuated much more intensively in the needles of damaged trees both in the diurnal and the seasonal courses than in those of undamaged ones, which implies that damaged trees respond more sensitively to the environmental conditions. ACC concentrations were the highest in summer and lowest in fall, while MACC concentrations seem…

PROOXIDATIVE MECHANISM OF ACTION OF PERACETIC ACID IN CELLULAR MODEL OF ACUTE PANCREATITIS

(Recensione a) ADELAIDE DE CHATELLUS Y MILAGROS EZQUERRO, ALEJANDRA PIZARNIK. EL LUGAR DONDE TODO SUCEDE, PARIS, L'HARMATTAN, 2013

2015

RECENSIONE A "ADELAIDE DE CHATELLUS Y MILAGROS EZQUERRO, 'ALEJANDRA PIZARNIK. EL LUGAR DONDE TODO SUCEDE', (2013, L'HARMATTAN), CHE RACCOGLIE CONTRIBUTI DI VARI STUDIOSI INTERNAZIONALI SULL'OPERA DI ALEJANDRA PIZARNIK

Metformin influences drug sensitivity in pancreatic cancer cells

2018

Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, highly metastatic malignancy and accounts for 85% of pancreatic cancers. PDAC patients have poor prognosis with a five-year survival of only 5–10% after diagnosis and treatment. Pancreatic cancer has been associated with type II diabetes as the frequency of recently diagnosed diabetics that develop pancreatic cancer within a 10-year period of initial diagnosis of diabetes in increased in comparison to non-diabetic patients. Metformin is a very frequently prescribed drug used to treat type II diabetes. Metformin acts in part by stimulating AMP-kinase (AMPK) and results in the suppression of mTORC1 activity and the induction o…

L'ANALISI PER INDICI DELLE AZIENDE VITIVINICOLE SICILIANE "GRANDI"

2021

THE BOOK EXAMINES ALL BIG SICILIAN WINERIES COMPANIES IN ORDER TO THIER FINANCIAL STATEMENT AND NET INCOME, WITH AN ANALYSE OF BALANCE SHEET IN THE LATEST THREE YEARS (2018-2020)

CAN ANCIENT DNA APPROACH DOCUMENT THE LOSS OF GENETIC DIVERSITY IN PYGMY CHIMPANZEES? A RESEARCH PROGRAM ON HISTORIC SAMPLES OF EUROPEAN PRIMATOLOGIC…

2009

Le valenze della Danza Movimento Terapia in presenza e a distanza. Corpo e relazioni durante la pandemia del COVID-19

2022

Elena Mignosi e Fernando Battista approfondiscono nella loro articolo le specificità della Danza Movimento Terapia (DMT) e i suoi numerosi ambiti applicativi (educativo, formativo clinico, terapeutico, sociale/inclusivo , riabilitativo). Conducono quindi una riflessione sulle modalità in presenza e da remoto, individuando quale efficacia possa avere partecipare ad un esperienza artisctico-creativa e corporea attraverso uno schermo. La pandemia da Covid 19 ha infatti reso necessario ripensare quelli che erano ritenuti i punti cardine del setting di DMT e di individuare nuove forme di interazione. Infine essi presentano brevemente i capitoli della rivista che costituiscono gli Atti del Conveg…

Asem ja uusi kansainvälinen järjestys : Euroopan ja Aasian yhteistyön vaikutus valtioiden suvereniteettiin

2010

Tutkimus tarkastelee Euroopan ja Aasian maiden yhteistyötä Asem-prosessin puitteissa. Asem-prosessi on monien hallintoviranomaisten kokousten kokonaisuus, jonka tärkeimmät päätökset tehdään kahden vuoden välein järjestettävissä hallitusten päämiesten huippukokouksissa. Tutkimuksen tarkoitus on selvittää, kuinka paitsi maanosien sisäinen integraatio, myös niiden välinen yhteistyö vaikuttavat osallistujavaltioiden suvereniteettiin. Tutkimuksen aineiston muodostaa Asem-huippukokousten yhteydessä julkaistut puheenjohtajan lausunnot ja huippukokouksissa julkaistut poliittiset ja temaattiset julistukset. EU:n ja Aseanin toiminnan kuvaamisessa olen lisäksi käyttänyt lähteinä näiden organisaatioide…

Entre Trapani et Tunis. De la période du Risorgimento à la fin du Protectorat français: parcours de travailleurs et d’entrepreneurs au-delà du Canal …

2019

Sin dai tempi più antichi, il Canale di Sicilia e la città di Trapani hanno costituito un ponte naturale fra il Maghreb e la Sicilia. Il saggio mette a sistema alcuni studi sugli architetti ed imprenditori di origine trapanese che emigrarono in Tunisia fra il XVIII e XIX secolo e ne propone una lettura inedita. Il fil rouge che lega Giuseppe Abita, la famiglia di imprenditori Canino e Domenico Basciano riguarda sia la loro provenienza dalla città siciliana, ma soprattutto l'importante contributo che essi hanno trasferito nell'architettura del periodo coloniale e post-coloniale francese nel Maghreb.

Selective downregulation of the MDR1 gene product in Caco-2 cells by stable transfection to prove its relevance in secretory drug transport.

2005

Considerable interest is focused on overcoming multidrug resistance (MDR) in cancer chemotherapy. The in vitro experiments to characterize P-glycoprotein's (P-gp) function and to decrease its effects have led to a variety of strategies such as addition of competitors or supplementation of the medium with oligonucleotides complementary to the 5'-end of the MDR1-mRNA. For the Caco-2 cell line, an in vitro model for absorption screening, expressing multiple transporters including P-gp, which pumps substances back into the apical solution, P-gp activity might mask other relevant transport proteins' activity. The objective of the present study was to construct a Caco-2 subline with reduced P-gp …