Search results for "papi"

showing 10 items of 636 documents

Usefulness of antimitochondrial antibody 113-1 in diagnosis and classification of salivary gland tumours with oncocytic differentiation

2010

Abstract Introduction and objectives Salivary gland tumours usually show great variability both in their morphopathology as well as their clinical behaviour. In the present study, the usefulness of antimitochondrial monoclonal antibody 113-1 in the diagnosis and categorization of salivary tumours was studied. Material and methods A series of 22 benign and malignant salivary tumours and 5 non-tumoral salivary gland specimens were immunohistochemically analysed using an antimitochondrial monoclonal antibody (Ab Mo 113-1), which recognises a non-glycosylated mitochondrial protein of 60 Kd. Results The use of this antibody allowed us to recognize all salivary tumours with oncocytic differentiat…

MalePathologymedicine.medical_specialtymedicine.drug_classMonoclonal antibodyPapillary CystadenomamedicineCarcinomaHumansAgedRetrospective StudiesSalivary glandbiologybusiness.industryAntibodies MonoclonalGeneral MedicineMiddle AgedSalivary Gland Neoplasmsmedicine.diseaseImmunohistochemistryMitochondriamedicine.anatomical_structureMonoclonalAntimitochondrial antibodybiology.proteinImmunohistochemistryFemaleAntibodybusinessActa Otorrinolaringologica (English Edition)
researchProduct

A binary genetic approach to characterize TRPM5 cells in mice

2015

International audience; Transient receptor potential channel subfamily M member 5 (TRPM5) is an important downstream signaling component in a subset of taste receptor cells making it a potential target for taste modulation. Interestingly, TRPM5 has been detected in extra-oral tissues; however, the function of extra-gustatory TRPM5-expressing cells is less well understood. To facilitate visualization and manipulation of TRPM5-expressing cells in mice, we generated a Cre knock-in TRPM5 allele by homologous recombination. We then used the novel TRPM5-IRES-Cre mouse strain to report TRPM5 expression by activating a tau GFP transgene. To confirm faithful coexpression of tau GFP and TRPM5 we gene…

MalePhysiologytaste papillaegene targetingBehavioral NeuroscienceMice0302 clinical medicineTaste receptor[SDV.IDA]Life Sciences [q-bio]/Food engineeringGene Knock-In TechniquesIn Situ Hybridization Fluorescence0303 health sciencestaste budsiresGene targetingrosa26ImmunohistochemistrySensory SystemsCell biologyknock inmedicine.anatomical_structuretrpm5taste receptor cellsFemaleGenotypeTransgeneCre recombinaseTRPM Cation ChannelsMice TransgenicBiologyAntibodiestgfpseptal organ of masera03 medical and health sciencesOlfactory MucosaTonguemicrovillar cellsPhysiology (medical)Gene knockinmedicineAnimals[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringTRPM5cre recombinaseAlleles030304 developmental biologyPalateMice Inbred C57BLvomeronasal organolfactory epitheliumgastrointestinal tractHomologous recombinationOlfactory epithelium030217 neurology & neurosurgery
researchProduct

Relocation of Papillary Muscles for Ischemic Mitral Valve Regurgitation

2014

Objective The assessment of the mitral valve apparatus (MVA) and its modifications during ischemic mitral regurgitation (IMR) is better performed by three-dimensional (3D) transesophageal echocardiography (TEE). The aim of our study was to carry out nonrestrictive mitral annuloplasty in addition to relocation of papillary muscles (PPMs) oriented by preoperative real-time 3D TEE through the mitral valve quantification dedicated software. Methods Since January 2008, a total of 70 patients with severe IMR were examined both before and after mitral valve repair. The mean (SD) coaptation depth and the mean (SD) tenting area were 1.4 (0.4) cm and 3.2 (0.5) cm2, respectively. Intraoperative 3D TEE…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyMitral Valve AnnuloplastyMyocardial ischemiamedicine.medical_treatmentTreatment outcomeMyocardial IschemiaEchocardiography Three-DimensionalThree-dimensional echocardiographyPapillary MuscleIschemic mitral valve regurgitationIntraoperative PeriodRetrospective StudieInternal medicineMitral valveMitral valve annuloplastymedicineHumansRetrospective StudiesAgedMitral valve repairIschemic mitral regurgitationbusiness.industryMitral Valve InsufficiencyGeneral MedicinePapillary Musclesmedicine.diseaseFeasibility StudieTreatment Outcomemedicine.anatomical_structureCardiologyFeasibility StudiesFemaleSurgeryIntraoperative PeriodbusinessMitral valve regurgitationCardiology and Cardiovascular MedicineMitral valve repairEchocardiography TransesophagealHumanInnovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
researchProduct

Optical coherence tomography angiography evaluation of peripapillary microvascular changes after rhegmatogenous retinal detachment repair

2021

PURPOSE To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. METHODS In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the corresponding areas of the healthy fellow eyes (control group). RESULTS Fifty-three eyes were included in the study. A significantly lower RPCP VD and RNFL thickness were observed in those subfields af…

MaleRetinal Ganglion Cellsgenetic structuresComputed Tomography Angiographymedicine.medical_treatmentNerve fiber layerVisual AcuityVitrectomyEyeradial peripapillary capillary plexuschemistry.chemical_compoundNerve FibersVitrectomyTomographyRetinal detachment repairRetinal detachmentGeneral MedicineMiddle AgedAxial Length Eyemedicine.anatomical_structureFemaleTomography Optical CoherencePars planamedicine.medical_specialtyBiometryOptic DiskEndotamponaderetinal detachmentOCT-angiography; Radial peripapillary capillary plexus; Retinal detachment; Retinal nerve fiber layer; Aged; Axial Length Eye; Biometry; Cross-Sectional Studies; Endotamponade; Female; Humans; Male; Middle Aged; Nerve Fibers; Optic Disk; Retinal Detachment; Retinal Ganglion Cells; Retinal Vessels; Retrospective Studies; Visual Acuity; Computed Tomography Angiography; Tomography Optical Coherence; VitrectomyOphthalmologymedicineHumansAxial LengthAgedRetrospective StudiesRetinabusiness.industryradial peripapillary capillary plexus; OCT-angiography; retinal nerve fiber layer; retinal detachmentRetinal Vesselsretinal nerve fiber layerRetinalOptical coherence tomography angiographymedicine.diseaseeye diseasesOphthalmologyCross-Sectional StudieschemistryOptical Coherencesense organsOCT-angiographybusiness
researchProduct

Differences in the Density of Fungiform Papillae and Composition of Saliva in Patients With Taste Disorders Compared to Healthy Controls

2017

International audience; This study investigated the relation of the fungiform taste papillae density and saliva composition with the taste perception of patients suffering from diagnosed taste disorders. For this purpose, 81 patients and 40 healthy subjects were included. Taste was measured by means of regional and whole mouth chemosensory tests, and electrogustometry. Olfaction was assessed using the Sniffin Sticks. Fungiform papillae were quantified using the "Denver Papillae Protocol for Objective Analysis of Fungiform Papillae". In addition, salivary parameters [flow rate, total proteins, catalase, total anti-oxidative capacity (TAC), carbonic anhydrase VI (caVI), and pH] were determine…

MaleSalivaTastefungiforme papillaePhysiology[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionsignal-detection measuresDentistryPhysiologyperceptiontasteBehavioral Neuroscience0302 clinical medicineMedicine030223 otorhinolaryngologyLingual papillaAged 80 and overElectrogustometryTaste PerceptionMiddle AgedTaste BudsSensory SystemsTaste disorderchorda tympani nerveFemalemedicine.symptomperformanceoleic-acidAdultgene polymorphismOlfactiontaste disordersbud density03 medical and health sciencesYoung Adultstomatognathic systemPhysiology (medical)HumansAgedsalivabusiness.industryBeck Depression Inventorytongue-regionAgeusiasensitivityCase-Control Studiesbusinessintensity[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
researchProduct

Factors affecting the intensity of epidermal papillomatosis in populations of roach, Rutilus rutilus (L.), estimated as scale coverage

2006

Studies of epidermal papillomatosis in fish populations have only rarely focused on the intensity of the disease, i.e. the number and size of papillomas. Furthermore, the methods used to evaluate the intensity of papillomatosis have not been standardized. We tested the reliability of a method based on counting of scales covered by papilloma tumours in roach, Rutilus rutilus (L). In addition, we studied the frequency distributions of the number of scales covered by papillomas within populations, evaluated the correlation between the prevalence and mean intensity of the disease among populations and examined the intensity of papillomatosis in roach with respect to sex and size of fish. Reliab…

MaleScale (anatomy)Veterinary medicineSkin NeoplasmsVeterinary (miscellaneous)CyprinidaeFish speciesFresh WaterPapillomatosisAquatic ScienceFish DiseasesSex FactorsPrevalencemedicineAnimalsBody SizeFinlandPapillomabiologyEcologybiology.organism_classificationIntensity (physics)Fish <Actinopterygii>FemaleEpidermisRutilusmedicine.symptomJournal of Fish Diseases
researchProduct

Validation and clinical use of the CECA, a disease-specific quality of life questionnaire for patients with anogenital Condylomata Acuminata

2008

Journal Article; Multicenter Study; Validation Studies; ECAVIm Study Group: I. Puedo, Centro ETS, Sevilla; J. Ballesteros, Clínica Sandoval, madrid; C. Colomo and A. Comunión, Centro ETS montesa, Madrid; X. Camino, Hospital Donosita, San Sebastián-Donosti; m. T. Arguisjuela, Centro ETS, Sevilla; J. m. Rojo, Hospital de Valme, Sevilla; J. Ferrando and E. barbera, CAP baix Ebre, Tarragona; J. Boronat, Hospital Joan XXIII, Tarragona; P. Herranz, Hospital La Paz, Madrid; M. Sabán, CAP Ronda de Torrasa, Barcelona; A. Sevila, Hospital de San Juan, Alicante; b. Escutia, Hospital de Elda, Alicante; b. Numancia, Centro ETS Ayuntamiento, Zaragoza; M. García Font, Hospital Mútua de Terrassa, Barcelona…

MaleSexually transmitted disease:Named Groups::Persons::Adult Children [Medical Subject Headings]:Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Rectal Diseases::Anus Diseases [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineSurveys and Questionnaireswarts:Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases Infectious::Skin Diseases Viral::Warts::Condylomata Acuminata [Medical Subject Headings]030212 general & internal medicineCuestionariosInfecciones por Papillomavirus:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]General MedicineVerrugas:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Sexual Behavior [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results [Medical Subject Headings]femaleCondylomata AcuminataFemaleGenital Diseases Male0305 other medical sciencepapillomavirus infections:Check Tags [Medical Subject Headings]AdultDisease specificmedicine.medical_specialtyPsychometricsEnfermedades de los genitales masculinosSexual Behavior:Check Tags::Male [Medical Subject Headings]Dermatologygenital diseasespsychology:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Psychometrics [Medical Subject Headings]03 medical and health sciencesmaleEnfermedades de los genitales femeninosmedicineHumans:Humanities::Humanities::Philosophy::Life::Quality of Life [Medical Subject Headings]Human papillomavirusEnfermedades del ano:Diseases::Female Urogenital Diseases and Pregnancy Complications::Female Urogenital Diseases::Genital Diseases Female [Medical Subject Headings]:Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases Infectious::Skin Diseases Viral::Warts [Medical Subject Headings]Anus Diseases030505 public healthCondiloma acuminadobusiness.industry:Diseases::Male Urogenital Diseases::Genital Diseases Male [Medical Subject Headings]Reproducibility of ResultsquestionnairesPsicologíaSurgeryquality of life:Diseases::Virus Diseases::Tumor Virus Infections::Papillomavirus Infections [Medical Subject Headings]Quality of LifeCalidad de Vidabusiness:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology Social [Medical Subject Headings]Genital Diseases FemaleHumanities
researchProduct

Vaccination against HPV-Associated Neoplasias

2014

Neoplasias associated with anogenital human papilloma viruses (HPV) are characterised by high patient morbidity and mortality and by appreciable limitations in the patientʼs quality of life. Each year 530,000 women worldwide and 4800 women in Germany develop cervical cancer 1, 2. Biomolecular and epidemiological studies carried out in the past 25 years have demonstrated causal link between persisting infections with HPV 16 and HPV 18 and at least 11 other so-called high-risk HPVs (HR-HPVs) and the development of cervical cancer and its precursor lesions (so-called dysplasias or, respectively, cervical intraepithelial neoplasias – CIN). HPV 16, HPV 18 and other HR-HPVs are also the causes of…

MaleSexually transmitted diseasemedicine.medical_specialtyGenital Neoplasms FemaleImmunization SecondaryMedizinHPV vaccinesGermanyMaternity and MidwiferymedicineHumansPenile cancerPapillomavirus VaccinesCervixGynecologyCervical cancerDose-Response Relationship Drugbusiness.industryPapillomavirus Infectionsvirus diseasesObstetrics and GynecologyGuidelinemedicine.diseaseDermatologyfemale genital diseases and pregnancy complicationsVaccinationmedicine.anatomical_structureGenital Neoplasms MaleFemaleSkin cancerbusiness
researchProduct

Epizootic cutaneous papillomatosis in roach Rutilus rutilus: sex and size dependence, seasonal occurrence and between-population differences.

2003

Epidemiology of epidermal papillomatosis in roach Rutilus rutilus was studied in 11 roach populations in Finland in 1999 and 2000 during the spawning period. In addition, the seasonal pattern of the disease was described in 1 population. Papilloma tumours were observed on the skin and fins of roach in 8 populations out of 11. Prevalence of papillomatosis varied from 0 to 62%, being higher in populations subject to industrial or sewage effluents. Males and large fish had higher prevalence of papilloma tumours. The disease outbreak peaked during the spawning period and signs of recovered skin on fish were observed later during the year. The gender dependence in the disease prevalence found in…

MaleSkin NeoplasmsPopulationPrevalenceCyprinidaeZoologyPapillomatosisAquatic ScienceDisease OutbreaksFish DiseasesImmunocompromised HostSex FactorsCyprinidaemedicineSeasonal breederPrevalenceAnimalseducationEcology Evolution Behavior and SystematicsEpizooticFinlandSkineducation.field_of_studybiologyPapillomaEcologyfungiWater PollutionOutbreakbiology.organism_classificationmedicine.diseaseLogistic ModelsBody ConstitutionFemaleSeasonsRutilusmedicine.symptomDiseases of aquatic organisms
researchProduct

Orthokeratinized odontogenic cysts: a Spanish tertiary care centre study based on HPV DNA detection

2018

Abstract Background The role of human papillomavirus (HPV) in orthokeratinized odontogenic cysts (OOCs) has rarely been studied. The objective is to describe the clinicopathological findings in a series of OOCs from a Spanish population that were investigated in relation to the possible presence of HPV. Methods A clinicopathological retrospective analysis followed by a molecular analysis of 28 high- and low-risk HPV genotypes was performed in OOC samples of patients seen during the last 15-years in a Spanish tertiary care center. Results Of 115 odontogenic cysts with keratinization, 16 cases of OOCs were confirmed and evaluated. OOCs occurred predominantly in the mandible of males (mean age…

MaleTertiary careCohort StudiesTertiary Care Centers0302 clinical medicineRecurrenceMedicinePapillomaviridaeBiopsy Needlevirus diseasesMiddle AgedImmunohistochemistryfemale genital diseases and pregnancy complicationsOdontogenicMolecular analysisHPV DNA detectionCell Transformation Neoplastic030220 oncology & carcinogenesisCarcinoma Squamous CellOral and maxillofacial surgeryMouth NeoplasmsAdultmedicine.medical_specialtyHPVAdolescentlcsh:Specialties of internal medicineDents MalaltiesRisk AssessmentYoung Adult03 medical and health scienceslcsh:RC581-951HumansMandibular DiseasesNeoplastic transformationGeneral DentistryRetrospective Studiesbusiness.industryOrthokeratinized odontogenic cystResearch030206 dentistryHigh- and low-riskDermatologyOtorhinolaryngologyOtorhinolaryngologySpainDNA ViralOdontogenic CystsEtiologyNeurology (clinical)HPV High- and low-risk Orthokeratinized odontogenic cyst RecurrencebusinessFollow-Up StudiesHead & Face Medicine
researchProduct