Search results for "particulate"

showing 10 items of 295 documents

Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special …

2013

Exposure of the respiratory tract to airborne particles (including metal-dusts and nano-particles) is considered as a serious health hazard. For a wide range of substances basic knowledge about the toxic properties and the underlying pathomechanisms is lacking or even completely missing. Legislation demands the toxicological characterization of all chemicals placed on the market until 2018 (REACH). As toxicological in vivo data are rare with regard to acute lung toxicity or exhibit distinct limitations (e.g. inter-species differences) and legislation claims the reduction of animal experiments in general ("3R" principle), profound in vitro models have to be established and characterized to m…

Cell SurvivalPulmonary toxicityMetal NanoparticlesToxicologyRisk AssessmentCell LineToxicologyBasic knowledgeToxicity Tests AcuteHumansMedicineInter-laboratoryInhalation ExposureReproducibilityLung toxicitybusiness.industryReproducibility of ResultsIn vitro exposureDustGeneral MedicineCritical parameterAlveolar Epithelial CellsParticulate MatterRadial flowBiochemical engineeringbusinessChemico-Biological Interactions
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In vitro impact preliminary assessment of airborne particulate from metalworking and woodworking industries.

2020

Abstract BackgroundInhalation is the main route of exposure to airborne pollutants. To evaluate the safety and assess the risks of occupational hazards different testing approaches are used. 3D airway epithelial tissues allow to mimic exposure conditions in vitro, generates human-relevant toxicology data, allows to elucidate mode of action of pollutants. ResultsGilian 3500 pumps equipped with Standard Midget Impingers were used to collect the airborne particulate from woodworking and metalworking environments. EpiAirway™ tissues were used to model half working day (4 h), full working day (8 h), and 3 working day exposures to occupational pollutants. Tissue viability was assessed using MTT a…

Cell biologyScienceArticleAndrologyOccupational ExposuremedicinebiochemistryHumansMTT assayParticle SizeLungGelsolinCell ProliferationA549 cellPollutantTissue SurvivalInhalation ExposureMultidisciplinaryInhalationChemistryCaspase 3Interleukin-6Gene Expression ProfilingQRWoodworkingIn vitro exposureParticulatesWoodEpitheliumIn vitromedicine.anatomical_structureGene Expression RegulationRisk factorsA549 CellsEnvironmental chemistryMetalworkingMetallurgyEnvironmental scienceMedicineParticulate MatterGelsolinHealth occupationsEnvironmental MonitoringScientific reports
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Viability and integrity of cell present in particulate bone collected during the preparation of the implant site: a preliminary study

2014

Aim: The aim of this study was to evaluate viability and integrity of cells (Osteoblasts and Osteocytes) present in the particulate bone (Bone Chips), obtained during the preparation of the implant site. Methods: Four patients aged between the IV and the VI decade presenting edentulous areas class III of Cawood and Howell were selected. All patients suffering from systemic and oral diseases and smoking were excluded. The surgeries were performed with the conventional technique, full-thickness flap, and the implant sites were prepared with large coils calibrated burs mounted on surgical micromotor at a speed of 600 rpm and external irrigation of saline solution previously cooled . The partic…

Cell viability particulate bone implantologySettore MED/28 - Malattie Odontostomatologiche
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Indoor Air Quality including Respiratory Viruses

2021

The detection of SARS-CoV-2 in indoor environments is a cause of increasing concern. In this study, three sampling methodologies have been used in order to collect SARS-CoV-2 and 17 other respiratory viruses in indoor air, combined with a new analytical process to analyze respiratory viruses. Different areas of an ophthalmological hospital were investigated for the presence of these airborne viruses. Moreover, indoor air quality (IAQ) parameters (carbon dioxide, CO2; carbon monoxide, CO; nitrogen dioxide, NO2; volatile organic compounds, VOCs; formaldehyde, HCHO; and particulate matter, PM) have been examined to study the relationship between IAQ and airborne viruses. All indoor air and sur…

Chemical Health and SafetySARS-CoV-2; air; sampling methodology; respiratory virus; indoor air qualityIndoor airSARS-CoV-2airChemical technologyHealth Toxicology and MutagenesisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Indoor bioaerosolTP1-1185ParticulatesToxicologyArticlerespiratory viruschemistry.chemical_compoundIndoor air qualitychemistryEnvironmental chemistryRespiratory virusEnvironmental sciencesampling methodologyNitrogen dioxideSampling methodologyindoor air qualityToxics; Volume 9; Issue 11; Pages: 274
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Precise Indication of Air Pollution Sources

2002

The present paper is a report of an application of Mossbauer spectroscopy, X-ray diffractometry, thermogravimetric analysis and PIXE in the characterization of the particulate matter in atmospheric aerosols in Vitoria Metropolitan Region (VMR), Brazil. The main sources of particulate matter, natural, industrial and antropogenic (from human activities), have been studied to identify its contribution in the atmospheric particles. Through the years 1995 to 1999 samples of total suspended particles (TSP, O ⩽; 100 μm) were collected from six points within VMR and in two points the inhalable particles (PM10, O ⩽ 10 μm). In addition, a receptor modeling was used helping in a precise indication of …

ChemistryEnvironmental chemistrySuspended particlesAir pollutionmedicineParticulatesmedicine.disease_causeInhalable particlesAerosol
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Extraction of lanthanides and actinides by a magnetically assisted chemical separation technique based on CMPO-calix[4]arenes

2001

A novel particulate system carrying CMPO ligands pre-organised on a calixarene scaffold has been synthesised and demonstrated to extract Eu3+, Am3+ and Ce3+ at high efficiency from simulated nuclear waste streams.

ChemistryExtraction (chemistry)Metals and AlloysRadioactive wasteGeneral ChemistryActinideCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsSolventChemical separationCalixareneMaterials ChemistryCeramics and CompositesParticulate systemNuclear chemistry
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Preliminary results about the breath of passive smokers and vapers based on the use of portable air monitoring devices

2016

Abstract Preliminary studies were made on the effect of both, classical smoking and electronic cigarettes (ECs) vaping, based on the quality of the indoor air and the breath of passive smokers. Portable air monitoring devices were used to evaluate carbon monoxide (CO), carbon dioxide (CO2), particulate materials (PM), formaldehyde and volatile organic compounds (VOCs) in indoor air and breath of active and passive smokers and vapers. As preliminary results, it can be observed that the major part of PMs liberated in classical smoking and ECs vaping correspond to the lowest size, which is the most dangerous for human health. However, the number of smallest PMs formed during vaping is around 5…

ChemistryIndoor airPassive Exposure010501 environmental sciences01 natural sciencesAnalytical Chemistry03 medical and health sciencesHuman healthAir monitoringchemistry.chemical_compound0302 clinical medicineCigarette smokingEnvironmental chemistryParticulate materialCarbon dioxide030212 general & internal medicineSpectroscopy0105 earth and related environmental sciencesMicrochemical Journal
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Characterization of functional groups of airborne particulate matter

2013

Particulate matter of organic combustibles burning consists of various hydrocarbons and radicals, which may cause harmful impact to human health. In this study solid particulate matter were collected on the filters from burning of various combustibles in a burning chamber and from atmosphere of city of Riga by dichotomous impactor. FTIR spectra were obtained before and after samples' treatment. Absorptions associated with aliphatic and aromatic hydrocarbons and alcohol functional groups were observed in the FTIR spectra. Free radicals of particulate matter were detected by electron paramagnetic resonance (EPR).

ChemistryRadicalInorganic chemistryAnalytical chemistryAlcoholParticulatesCharacterization (materials science)law.inventionFtir spectraAtmosphereHuman healthchemistry.chemical_compoundlawElectron paramagnetic resonanceIOP Conference Series: Materials Science and Engineering
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Medical Geochemistry

2013

Preface.- How trace element contents in bronchoalveolar lavages can probe the human exposure to inhaled particulates.- Geochemistry and Biochemistry - insights into the fate and transport of Pt-based chemotherapy drugs.- Atmospheric Particulate Matter (PM) in the Middle East: Toxicity, trans-boundary transport and influence of synoptic conditions.- Reaction path modeling: theoretical aspects and applications.- An observation on the composition of urinary calculi: environment influence.- Magnetite minerals in the human brain: what's their role?.- Chemometrics and Medical Geochemistry: A brief tutorial.- Dust, metals and metalloids in the environment: from air to hair.- Metal Geochemistry of …

Chemotherapy DrugsEnvironmental chemistryGeochemistry medical geochemistryTrace element compositionGeochemistryTrace elementHuman boneMetalloidGeological materialsReaction pathParticulatesGeology
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Molecular Characterization and Source Identification of Atmospheric Particulate Organosulfates Using Ultrahigh Resolution Mass Spectrometry.

2019

Organosulfates (OSs) have been observed as substantial constituents of atmospheric organic aerosol (OA) in a wide range of environments; however, the chemical composition, sources, and formation mechanism of OSs are still not well understood. In this study, we first created an "OS precursor map" based on the elemental composition of previous OS chamber experiments. Then, according to this "OS precursor map", we estimated the possible sources and molecular structures of OSs in atmospheric PM2.5 (particles with aerodynamic diameter ≤ 2.5 μm) samples, which were collected in urban areas of Beijing (China) and Mainz (Germany) and analyzed by ultrahigh-performance liquid chromatography (UHPLC) c…

China010501 environmental sciencesOrbitrapMass spectrometry01 natural sciencesMass Spectrometrylaw.inventionchemistry.chemical_compoundlawGermanyEnvironmental ChemistryChemical compositionIsoprene0105 earth and related environmental sciencesAerosolsAir PollutantsSulfatesGeneral ChemistryParticulatesCharacterization (materials science)AerosolchemistryEnvironmental chemistryBeijingGlyoxalEnvironmental MonitoringEnvironmental sciencetechnology
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