Search results for "patch"
showing 10 items of 337 documents
Photonic controlled metasurface for intelligent antenna beam steering applications including 6G mobile communication systems
2023
This paper presents a novel metasurface antenna whose radiation characteristics can be remotely controlled by optical means using PIN photodiodes. The proposed reconfigurable antenna is implemented using a single radiating element to minimize the size and complexity. The antenna is shown to exhibit a large impedance bandwidth and is capable of radiating energy in a specified direction. The proposed antenna consists of a standard rectangular patch on which is embedded an H-tree shaped fractal slot of order 3. The fractal slot is used to effectively reduce the physical size of the patch by 75 % and to enhance its impedance bandwidth. A metasurface layer is strategically placed above the patch…
Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium
2019
Background Voltage-gated sodium (Nav) channels have traditionally been considered a trademark of excitable cells. However, recent studies have shown the presence of Nav channels in several non-excitable cells, such as astrocytes and macrophages, demonstrating that the roles of these channels are more diverse than was previously thought. Despite the earlier discoveries, the presence of Nav channel-mediated currents in the cells of retinal pigment epithelium (RPE) has been dismissed as a cell culture artifact. We challenge this notion by investigating the presence and possible role of Nav channels in RPE both ex vivo and in vitro. Results Our work demonstrates that several subtypes of Nav cha…
Design of a Compact Dual Circular-Polarized Antenna for L-Band Satellite Applications
2020
In this paper, we propose the design of a dual circular-polarized antenna for L-band applications (1.1-1.6 GHz). The designed antenna has been developed by considering crossed-dipoles on top of which a circular patch has been placed to properly act on the mutual coupling between the dipoles. The dual circular polarization is achieved by feeding dipoles in quadrature. Moreover, to increase the antenna gain and polarization purity at high elevation angles, a fence of passive monopoles has been added. The proposed antenna can profitably used as primary feed of a low-frequency parabolic reflector.
Scaling laws in the distribution of galaxies
2004
Research done during the previous century established our Standard Cosmological Model. There are many details still to be filled in, but few would seriously doubt the basic premise. Past surveys have revealed that the large-scale distribution of galaxies in the Universe is far from random: it is highly structured over a vast range of scales. To describe cosmic structures, we need to build mathematically quantifiable descriptions of structure. Identifying where scaling laws apply and the nature of those scaling laws is an important part of understanding which physical mechanisms have been responsible for the organization of clusters, superclusters of galaxies and the voids between them. Find…
<i>In vitro</i> Modeling of Ryanodine Receptor 2 Dysfunction Using Human Induced Pluripotent Stem Cells
2011
Background/Aims: Induced pluripotent stem (iPS) cells generated from accessible adult cells of patients with genetic diseases open unprecedented opportunities for exploring the pathophysiology of human diseases in vitro. Catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) is an inherited cardiac disorder that is caused by mutations in the cardiac ryanodine receptor type 2 gene (RYR2) and is characterized by stress-induced ventricular arrhythmia that can lead to sudden cardiac death in young individuals. The aim of this study was to generate iPS cells from a patient with CPVT1 and determine whether iPS cell-derived cardiomyocytes carrying patient specific RYR2 mutation recap…
Physostigmine and Neuromuscular Transmission
1993
Single channel studies carried out in cultured rat myoballs and cultured hippocampal neurons, and ion flux studies performed on Torpedo electrocyte membrane vesicles, showed that physostigmine (Phy), a well-established acetylcholinesterase inhibitor, interacts directly with nicotinic acetylcholine receptors (nAChR). Low concentrations (0.1 microM) of Phy activate the receptor integral channel, whereas higher concentrations blocked the channel in its opened state. In contrast to channel activation by acetylcholine (ACh) and classical cholinergic agonists, however, Phy was capable of activating the nAChR channel even when the ACh binding sites were blocked by competitive antagonists, such as …
A boundary element model for piezoelectric dynamic strain sensing of cracked structures
2011
A piezoelectric sensor model is here presented for the Structural Health Monitoring (SHM) of damaged structures. A boundary element approach based on the Dual Reciprocity BEM is then used to model and analyze the transient response of a piezoelectric patch bonded on a cracked beam. The BE model is written for the piezoelectric problem employing generalized displacements. The multidomain boundary element technique is implemented to model non-homogeneous and cracked configuration, taking contact conditions into account. Analyses have been carried out for an isotropic beam with a piezoelectric strip attached on it and dynamical results for the undamaged structure have been compared with FE res…
Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32.
2010
According to previously published ultrastructural studies, oligodendrocytes in white matter exhibit gap junctions with astrocytes, but not among each other, while in vitro oligodendrocytes form functional gap junctions. We have studied functional coupling among oligodendrocytes in acute slices of postnatal mouse corpus callosum. By whole-cell patch clamp we dialyzed oligodendrocytes with biocytin, a gap junction-permeable tracer. On average 61 cells were positive for biocytin detected by labeling with streptavidin-Cy3. About 77% of the coupled cells stained positively for the oligodendrocyte marker protein CNPase, 9% for the astrocyte marker GFAP and 14% were negative for both CNPase and GF…
Patch size and connectivity influence the population turnover of the threatened chequered blue butterfly, Scolitantides orion (Lepidoptera: Lycaenida…
2008
Chequered blue butterfly, Scolitantides orion (Lepidoptera: Lycaenidae) has severely declined in many parts of Europe and is currently red-listed in many countries. We studied the population structure and turnover of the species in a lake-island system in a National Park in eastern Finland over a three-year period. The incidence of the chequered blue on the suitable islands (n = 41) and habitat patches (n = 123) was high: an average of 82% of the islands and patches were occupied over the three year period. At the island scale, the annual population turnover rate was 17%, with an extinction and colonization rate of 7% and 10%, respectively. At the patch scale, the annual population turnover…
Optogenetically Controlled Activity Pattern Determines Survival Rate of Developing Neocortical Neurons
2021
A substantial proportion of neurons undergoes programmed cell death (apoptosis) during early development. This process is attenuated by increased levels of neuronal activity and enhanced by suppression of activity. To uncover whether the mere level of activity or also the temporal structure of electrical activity affects neuronal death rates, we optogenetically controlled spontaneous activity of synaptically-isolated neurons in developing cortical cultures. Our results demonstrate that action potential firing of primary cortical neurons promotes neuronal survival throughout development. Chronic patterned optogenetic stimulation allowed to effectively modulate the firing pattern of single ne…