Search results for "pathogenic"

Deciphering the role of insertion sequences in the evolution of bacterial epidemic pathogens with panISa software

2020

Next-generation sequencing (NGS) is now widely used in microbiology to explore genome evolution and the structure of pathogen outbreaks. Bioinformatics pipelines readily detect single-nucleotide polymorphisms or short indels. However, bacterial genomes also evolve through the action of small transposable elements called insertion sequences (ISs), which are difficult to detect due to their short length and multiple repetitions throughout the genome. We designed panISa software for the ab initio detection of IS insertions in the genomes of prokaryotes. PanISa has been released as open source software (GPL3) available from https://github.com/bvalot/panISa. In this study, we assessed the utilit…

Contribution of studies on suppressive soils to the identification of bacterial biocontrol agents and to the knowledge of their modes of action

2007

International audience

Natural soil reservoirs for human pathogenic and fecal indicator bacteria

2015

Prod ? EA UB INRA BIOME; International audience; résumé du livre : Environmental microbiology, the study of the roles that microbes play in all planetary environments, is one of the most important areas of scientific research. The The Manual of Environmental Microbiology, Fourth Edition, provides comprehensive coverage of this critical and growing field. Thoroughly updated and revised, the Manuall is the definitive reference for information on microbes in air, water, and soil and their impact on human health and welfare. Written in accessible, clear prose, the manual covers four broad areas: general methodologies, environmental public health microbiology, microbial ecology, and biodegradati…

Intérêt des modèles cellulaires d'interaction dans l'étude du pouvoir pathogène des colibacilles producteurs de CNF et des colibacilles responsables …

1995

Adhesion and cytopathic effect mutants: towards new oral vaccines against rabbit O103 colibacillosis

1994

Ecological role of mycotoxin and consequences of the presence of mycotoxins in crop residues on the survival and pathogenic activity of Fusarium gram…

2010

Modes of action for biological control of Fusarium wilt of banana using non-pathogenic Fusarium oxysporum

2006

Role of adhesive factor/rabbit2 in experimental enteropathogenic Eschiria coli O103 diarrhea of weaned rabbit

1996

International audience

Vaccination orale contre les infections par les REPEC grâce à une souche bactérienne vivante atténuée double mutante

1999

National audience

Enteropathogenic Escherichia coli O103 from rabbit elicits actin stress fibers and focal adhesions in HeLa epithelial cells, cytopathic effects that …

1997

Escherichia coli O103, a major agent of weaned-rabbit diarrhea in Western Europe, was previously shown to produce diarrhea and attaching-and-effacing intestinal lesions in experimentally infected rabbits and to possess a homolog of the eaeA gene of enteropathogenic E. coli (EPEC). In the present study, we have shown that although negative in the fluorescent-actin staining test on HeLa cells, prototype rabbit E. coli O103 strain B10 was able to induce an original cytopathic effect (CPE) in the same interaction model. This CPE was characterized by a generalized reorganization of the actin cytoskeleton and the formation of focal adhesions on the entire surface of the target cells. These effect…