Search results for "pattern"

showing 10 items of 4203 documents

Application of a model for the evaluation of the “Visitor Satisfaction” in a nature reserve of South Italy

2017

The protected natural area represents an important resource because from it sustainable and long-lasting social and economic development processes can start. In fact, the conservation of biodiversity can help create economic values by using natural capital which, if properly valorised, can help the momentum of local sustainable development and create diffuse welfare in terms of employment and income. To such a purpose, the evaluation both of the demand by those who enjoy the services of a protected area and of the level of satisfaction that visitors draw from their experience becomes a priority. The present study aims at investigating the behaviour and the preferences of the visitors to a p…

Nature reservebusiness.industryVisitor patternassessmentEnvironmental resource managementSoil ScienceForestrylocal developmentprotected areas; recreational services; local development; assessment; preferences; Sicilyrecreational serviceprotected areaSettore AGR/01 - Economia Ed Estimo RuraleBusinesspreferenceSicily
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Adaptative air traffic network: Statistical regularities in air traffic management

2016

Starting from traffic data on flights trajectories-planned and actual ones-in Europe, we build a navigation point network. We study this network which exhibits different features for different European countries. In particular, some countries uses a high number of navpoints, facilitating the planning of the flight plan by air companies at the cost of higher concentrations of traffic in few nodes. Making use of the deviations from the planned trajectories, we find that once again different countries have different control procedures with respect to traffic management. Interestingly, we find that some countries tend to make more deviations when the traffic conditions are low. Moreover, they t…

Navigation point networkControl and Systems EngineeringTraffic flow managementCommunicationNetwork scienceGeography Planning and DevelopmentAerospace EngineeringComputer Science Applications1707 Computer Vision and Pattern RecognitionTransportationStatistical modelSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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Redox signaling in acute pancreatitis

2015

Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium, cathepsins, pH disorders, autophagy, and cell death, particularly necrosis. This review focuses on the new role of redox signaling in acute pancreatitis. Oxidative stress and redox status are involved in the onset of acute pancreatitis and also in the development of the systemic inflammatory response, being glutathione depletion, xanthine oxidase activation, and thiol oxidation in proteins critical features of the disease in the pancreas. On th…

NecrosisGSH reduced glutathioneSTAT3 signal transducer and activator of transcription 3ERK extracellular signal-regulated kinasesClinical BiochemistryCCK cholecystokininTRAFs TNF receptor associated factorsReview ArticleIκB kinasePharmacologymedicine.disease_causeBiochemistrySHP small heterodimer partnerSTIM1 stromal interaction molecule 1chemistry.chemical_compoundHATs histone acetyltransferasesMedicineASK1GCL glutamate cysteine ligaseTNF-α tumor necrosis factor alphaIKK IκB kinaseNOS nitric oxide synthaseAcute inflammationHIF hypoxia inducible factorlcsh:QH301-705.5NF-κB nuclear factor kappa BDAMPs damage-associated molecular pattern moleculeslcsh:R5-920biologyGSSG oxidized glutathioneNF-kappa BNLRs nucleotide-binding oligomerization domain (NOD) like receptorsTRADD tumor necrosis factor receptor type 1-associated DEATH domain proteinTRPC3 transient receptor potential channel 3VEGF vascular endothelial growth factorGlutathioneTNFR tumor necrosis factor receptorHMGB1 high-mobility group Box 1 proteinIP3R inositol 145-trisphosphate receptor type 3VCAM-1 Vascular Cell adhesion protein 1Acute DiseaseJNK c-Jun N-terminal kinaseAcute pancreatitisTLRs toll-like receptorsmedicine.symptomlcsh:Medicine (General)Oxidation-ReductionAP-1 activator protein-1Signal TransductionmRNA messenger ribonucleic acidHMGB1ASC apoptosis-associated speck-like protein containing a carboxy-terminal CARDRNS reactive nitrogen speciesPTPs protein tyrosine phosphatasesROS reactive oxygen speciesNADH nicotinamide adenine dinucleotidepHe extracellular pHFAEE fatty acid ethyl estersAP acute pancreatitisHumansXanthine oxidaseCBP CREB-binding proteinRyR endoplasmic reticulum membrane ryanodine receptorsMDA malondialdehydeNO nitric oxideXO xanthine oxidaseASK1 apoptosis signal-regulating kinase-1business.industryOrganic ChemistryAutophagyNADPH nicotinamide adenine dinucleotide phosphateHDACs histone deacetylasesmedicine.diseaseCARS compensatory anti-inflammatory response syndromeXDH xanthine dehydrogenaseIL interleukinIκB inhibitor of kappa BAcute pancreatitisETC Electron transport chainPancreatitisMKPs MAPK phosphatasesSAP severe acute pancreatitischemistrylcsh:Biology (General)DTT dithiothreitolOxidative stressNAC N-acetyl cysteineImmunologybiology.proteinCalciumLysosomesReactive Oxygen SpeciesbusinessMAPK mitogen-activated protein kinaseOxidative stressERCP endoscopic retrograde cholangiopancreatographyRedox Biology
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Bedside surgery in the newborn infants: Survey of the Italian society of pediatric surgery

2020

Abstract Introduction This is the report of the first official survey from the Italian Society of Pediatric Surgery (ISPS) to appraise the distribution and organization of bedside surgery in the neonatal intensive care units (NICU) in Italy. Methods A questionnaire requesting general data, staff data and workload data of the centers was developed and sent by means of an online cloud-based software instrument to all Italian pediatric surgery Units. Results The survey was answered by 34 (65%) out of 52 centers. NICU bedside surgery is reported in 81.8% of the pediatric surgery centers. A lower prevalence of bedside surgical practice in the NICU was reported for Southern Italy and the islands …

Neonatal intensive care unitmedicine.medical_treatmentPractice PatternsReviewBedside surgeryNeonatal intensive care unit Bedside surgery Operative room Intrahospital transport Critically ill neonates0302 clinical medicineInformed consentNeonatalSurveys and QuestionnairesPediatric surgeryPractice Patterns Physicians'Societies MedicalBedside surgery; Critically ill neonates; Intrahospital transport; Neonatal intensive care unit; Operative roomlcsh:RJ1-570Operative roomOperativeCritically ill neonatesIntensive Care UnitsPneumothoraxItaly030220 oncology & carcinogenesisSurgical Procedures OperativeCentral venous catheterInfant Prematuremedicine.medical_specialtyPerforation (oil well)Critically ill neonate03 medical and health sciencesNeonatal intensive care unitMedical030225 pediatricsIntensive careIntensive Care Units NeonatalmedicineHumansPrematureContraindicationPhysicians'Surgical Proceduresbusiness.industryBedside surgery Critically ill neonates Intrahospital transport Neonatal intensive care unit Operative room Humans; Infant Newborn Infant Premature Italy Practice Patterns Physicians' Societies Medical Surveys and Questionnaires Intensive Care Units Neonatal Surgical Procedures OperativeInfant NewbornInfantlcsh:PediatricsIntrahospital transportNewbornmedicine.diseaseSurgeryOperative room.Settore MED/20Societiesbusiness
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New European Discovery of Splachnum pensylvanicum (Bryophyta, Splachnaceae) in Lithuania, with Taxonomic Notes and a Review of Its World Distribution

2021

Splachnum pensylvanicum (Brid.) Grout ex H.A.Crum is recorded for the first time in Lithuania and it is its fourth discovery at a third locality in Europe. It was found for the first time in 2000 in Kamanos mire, the largest peatland complex in the northern part of this East Baltic country. Targeted investigations at this site in 2017 resulted in the discovery of 14 populations and it is apparently the largest and most abundant locality of the species in Europe. Splachnum pensylvanicum is briefly described and illustrated along with some taxonomic notes and a detailed description of its habitat requirements. The global geographical distribution of S. pensylvanicum is reviewed and mapped. It…

NeotropicsEcologyEuro‐American distribution patternEuro-American distribution patternBotanyKamanos mire; NeotropicsPlant ScienceKamanos mireBaltic countries; coprophilous mosses; Euro-American distribution pattern; Kamanos mire; Neotropics; North AmericaQK1-989North AmericaEcology Evolution Behavior and SystematicsBaltic countriescoprophilous mossesPlants
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Ems and Nkx6 are central regulators in dorsoventral patterning of the Drosophila brain

2009

In central nervous system development, the identity of neural stem cells (neuroblasts) critically depends on the precise spatial patterning of the neuroectoderm in the dorsoventral (DV) axis. Here, we uncover a novel gene regulatory network underlying DV patterning in the Drosophila brain, and show that the cephalic gap gene empty spiracles (ems) and the Nk6 homeobox gene (Nkx6) encode key regulators. The regulatory network implicates novel interactions between these and the evolutionarily conserved homeobox genes ventral nervous system defective (vnd), intermediate neuroblasts defective (ind) and muscle segment homeobox (msh). We show that Msh cross-repressively interacts with Nkx6 to sust…

Nervous systemEmbryo Nonmammaliananimal structuresBiologyNeuroblastmedicineAnimalsDrosophila ProteinsMolecular BiologyGap geneBody PatterningHomeodomain ProteinsGeneticsRegulation of gene expressionNeuroectodermNeural tubeBrainGene Expression Regulation DevelopmentalCell biologymedicine.anatomical_structureVentral nerve cordembryonic structuresHomeoboxDrosophilaTranscription FactorsDevelopmental BiologyDevelopment
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The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of Drosophila.

2006

International audience; In Drosophila, evolutionarily conserved transcription factors are required for the specification of neural lineages along the anteroposterior and dorsoventral axes, such as Hox genes for anteroposterior and columnar genes for dorsoventral patterning. In this report, we analyse the role of the columnar patterning gene ventral nervous system defective (vnd) in embryonic brain development. Expression of vnd is observed in specific subsets of cells in all brain neuromeres. Loss-of-function analysis focussed on the tritocerebrum shows that inactivation of vnd results in regionalized axonal patterning defects, which are comparable with the brain phenotype caused by mutatio…

Nervous systemMutantApoptosis0302 clinical medicineMESH: Gene Expression Regulation DevelopmentalDrosophila ProteinsMESH: AnimalsAxonHox geneMESH: MelatoninGenetics0303 health sciencesMESH: Pineal GlandBrainGene Expression Regulation DevelopmentalMESH: Transcription FactorsNeuromerePhenotypeBiological EvolutionCell biologymedicine.anatomical_structureDrosophila melanogasterPhenotypeMESH: Photic StimulationMESH: Body PatterningMESH: MutationMESH: Drosophila ProteinsBiologyMESH: PhenotypeMESH: Drosophila melanogaster03 medical and health sciencesMESH: BrainNeuroblastMESH: EvolutionMESH: Homeodomain ProteinsmedicineAnimalsMESH: Circadian RhythmMolecular Biology030304 developmental biologyBody PatterningHomeodomain ProteinsMESH: HumansMESH: ApoptosisEmbryogenesis[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyMESH: LightMutationMESH: SerotoninMESH: Seasons030217 neurology & neurosurgeryDevelopmental BiologyTranscription Factors
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Extracellular Vesicle-Mediated Cell–Cell Communication in the Nervous System: Focus on Neurological Diseases

2019

Extracellular vesicles (EVs), including exosomes, are membranous particles released by cells into the extracellular space. They are involved in cell differentiation, tissue homeostasis, and organ remodelling in virtually all tissues, including the central nervous system (CNS). They are secreted by a range of cell types and via blood reaching other cells whose functioning they can modify because they transport and deliver active molecules, such as proteins of various types and functions, lipids, DNA, and miRNAs. Since they are relatively easy to isolate, exosomes can be characterized, and their composition elucidated and manipulated by bioengineering techniques. Consequently, exosomes appear…

Nervous systemReviewCell CommunicationTheranostic NanomedicineCatalysilcsh:Chemistry0302 clinical medicineCell–cell interactionlcsh:QH301-705.5Tissue homeostasisSpectroscopyDrug Carriers0303 health sciencesnervous systemCell DifferentiationNeurodegenerative DiseasesComputer Science Applications1707 Computer Vision and Pattern RecognitionGeneral MedicineExtracellular vesicleComputer Science ApplicationsCell biologymedicine.anatomical_structureTheranostics toolExtracellular vesicleextracellular vesiclesneurological diseasesCell signalingCell typecell–cell interactionexosomesBiologyCatalysisInorganic Chemistry03 medical and health sciencesExtracellularmedicineCell-cell interactionHumansPhysical and Theoretical ChemistryMolecular Biology030304 developmental biologytheranostics toolsOrganic ChemistrybiomarkersBiomarkercentral nervous systemMicrovesiclesExosomelcsh:Biology (General)lcsh:QD1-999030217 neurology & neurosurgeryNeurological diseaseInternational Journal of Molecular Sciences
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Segment-specific requirements for dorsoventral patterning genes during early brain development in Drosophila.

2006

An initial step in the development of the Drosophila central nervous system is the delamination of a stereotype population of neural stem cells (neuroblasts, NBs) from the neuroectoderm. Expression of the columnar genes ventral nervous system defective (vnd), intermediate neuroblasts defective (ind) and muscle segment homeobox (msh) subdivides the truncal neuroectoderm(primordium of the ventral nerve cord) into a ventral, intermediate and dorsal longitudinal domain, and has been shown to play a key role in the formation and/or specification of corresponding NBs. In the procephalic neuroectoderm(pNE, primordium of the brain), expression of columnar genes is highly complex and dynamic, and th…

Nervous systemanimal structuresCentral nervous systemPopulationBiologyNeuroblastmedicineAnimalsDrosophila ProteinseducationMolecular BiologyIn Situ HybridizationBody PatterningHomeodomain Proteinseducation.field_of_studyNeuroectodermBrainGene Expression Regulation DevelopmentalAnatomyNeural stem cellCell biologymedicine.anatomical_structureDrosophila melanogasterVentral nerve cordembryonic structuresHomeoboxNeurogliaDevelopmental BiologyTranscription FactorsDevelopment (Cambridge, England)
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Kinerja Sapi Bali Jantan yang diberikan pakan Rumput Gajah (Punnisetum purpureum) subtitusi fermentasi Jerami Padi

2018

The research was aimed to study Bali bulls fed with Pennisetum purpureum with fermented rice straws substitution in Manokwari Regency, West Papua was conducted experimentally with 12 Bali bulls that have average weight of 176.02±38.35 kg with 2 – 2,5 years old for 5 months duration. The study was designed using complete randomized design of nested pattern with 3 (three) treatments, 4 (four) replications and 4 (four) times weighing, with an assumption that Bali bulls are nested during weighing time. The results of this study showed that Penicetum purpureum substitution with fermented straws did not significant on Bali bulls body weight. The duration of fermented rice straws feeding that subs…

Nested PatternAnimal sciencemedicineGeneral MedicineRice strawPennisetum purpureummedicine.symptomBiologybiology.organism_classificationBody weightWeight gainCompletely randomized designBali cattleCassowary
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