Search results for "pause"

showing 10 items of 467 documents

Spanish Menopause Society position statement: Use of denosumab in postmenopausal women

2014

Denosumab is a new drug developed for the treatment of osteoporosis. Moreover, increasing evidences link denosumab with benefits in cancer, an area of interest for those in charge of the postmenopausal health. Denosumab has shown efficacy in the control of bone loss associated with hypogonadic states created by chemotherapy in breast and other cancers. Moreover, some studies reveal efficacy in reducing the progression of metastases. A panel of experts from the Spanish Menopause Society has met to develop usage recommendations based on the best available evidence.

Position statementOncologymedicine.medical_specialtyInjections SubcutaneousOsteoporosisBone NeoplasmsBreast NeoplasmsGeneral Biochemistry Genetics and Molecular BiologyFractures BoneBreast cancerBone DensityInternal medicinemedicineHumansOsteoporosis PostmenopausalPostmenopausal womenBone Density Conservation Agentsbusiness.industryObstetrics and GynecologyCancerArea of interestmedicine.diseasePostmenopauseMenopauseDenosumabDisease ProgressionPhysical therapyFemaleBone RemodelingDenosumabSafetybusinessmedicine.drugMaturitas
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Sex differences in obstructive sleep apnoea.

2019

Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status,e.g.menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea–hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyPediatricsSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineSex FactorsRisk FactorsEpidemiologymedicineInsomniaHumanslcsh:RC705-779PregnancySleep Apnea Obstructivewomen upper airways sleepbusiness.industrySleep apnealcsh:Diseases of the respiratory systemAirway obstructionmedicine.diseaseSleep in non-human animalsrespiratory tract diseasesMenopause030228 respiratory systemFemalePresentation (obstetrics)medicine.symptombusinessEuropean respiratory review : an official journal of the European Respiratory Society
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Asthma and menopause

2016

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Pulmonary and Respiratory MedicineMenopausePediatricsmedicine.medical_specialtybusiness.industrylcsh:Rmedicinelcsh:MedicineCardiology and Cardiovascular Medicinemedicine.diseasebusinessAsthma
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Role of menopause and hormone replacement therapy in sleep-disordered breathing

2020

There are suggestions that the loss of female sex hormones following menopause is critical for the development or progression of sleep-disordered breathing (SDB). We conducted a review of the literature on the role of menopause and hormone replacement therapy (HRT) in SDB risk. There is an increase in SDB during the menopausal transition period, but data on an effect beyond that of increasing age and changes in body habitus are weak or absent. Early community-based, observational studies reported a protective effect by HRT on SDB prevalence, but this could possibly be explained as a healthy user effect. Interventional studies of the effect of HRT on SDB are sparse, with only a few randomize…

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtymedicine.drug_classSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesSleep Apnea Syndromes0302 clinical medicineWomanPhysiology (medical)mental disordersPrevalenceHumansMedicineObesitycardiovascular diseasesSleep-disordered breathingbusiness.industrymedicine.diseaseEstrogenObstructive sleep apneaObesitynervous system diseasesrespiratory tract diseasesObstructive sleep apneaMenopauseMetabolismHormone replacement therapy030228 respiratory systemNeurologyEstrogenTransgender hormone therapySleep disordered breathingFemaleObservational studysense organsNeurology (clinical)Menopausebusiness030217 neurology & neurosurgeryHormoneSleep Medicine Reviews
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Comparison of soft tissue body composition in postmenopausal women with or without hormone replacement therapy considering the influence of reproduct…

2001

To examine long-term effects of at least 5 years' conventional hormone replacement therapy (HRT), reproductive history and lifestyle on fat mass and muscle mass in postmenopausal women.A cross-sectional retrospective approach was used, including 64 healthy women (56-69 years, mean age 63.4 years). Hormone users were compared with age-matched non-users with respect to (a) type of HRT used (oestrogen vs oestrogen plus gestagen vs no hormones), (b) categories of oestrogens used (oestradiol-based oestrogens vs conjugated equine oestrogens vs no oestrogens) and (c) categories of gestagens used (testosterone derivatives vs progesterone derivatives vs no gestagens). Data on hormone use, reproducti…

Research designAgingmedicine.medical_specialtyPhysiologyEpidemiologyHormone Replacement TherapyPhysiologySurveys and QuestionnairesGeneticsElectric ImpedanceMedicineHumansLife StyleTestosteroneAgedRetrospective StudiesGynecologyAnalysis of VariancePostmenopausal womenAnthropometrybusiness.industryPublic Health Environmental and Occupational HealthSoft tissueMiddle AgedPhysical activity levelPostmenopauseCross-Sectional StudiesTransgender hormone therapyCase-Control StudiesMenarcheBody CompositionFemalebusinessHormoneAnnals of human biology
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Pre-invasion history and demography shape the genetic variation in the insecticide resistance-related acetylcholinesterase 2 gene in the invasive Col…

2012

Abstract Background Invasive pest species offers a unique opportunity to study the effects of genetic architecture, demography and selection on patterns of genetic variability. Invasive Colorado potato beetle (Leptinotarsa decemlineata) populations have experienced a rapid range expansion and intense selection by insecticides. By comparing native and invasive beetle populations, we studied the origins of organophosphate (OP) resistance-associated mutations in the acetylcholinesterase 2 (AChE2) gene, and the role of selection and demography on its genetic variability. Results Analysis of three Mexican, two US and five European populations yielded a total of 49 haplotypes. Contrary to the exp…

Resistenssin evoluutio0106 biological sciencesInsecticidesDNA Mutational AnalysisGenes Insect01 natural sciencesInsecticide ResistanceJuvenile hormone esteraseDiapause protein 1Genetics0303 health sciencesbiologytulokaslajitMajor geneOrganophosphatesJuveniilihormoniesteraasiColeopteraTuholaistorjunta-aineresistenssiAcetylcholinesteraseInvaasiobiologiaAsetyylikoliiniesteraasiResearch ArticlePesticide resistanceEvolutionPesticide resistanceLocus (genetics)valinta03 medical and health sciencesGenetic variationQH359-425AnimalsGenetic variabilityDiapaussiproteiini 1SelectionEcology Evolution Behavior and SystematicsSolanum tuberosum030304 developmental biologyGenetic diversityInvasive speciesColorado potato beetleGenetic VariationResistance evolutionbiology.organism_classification010602 entomologyGenetics PopulationPopulation bottleneckHaplotypesInvasiolajiMutationIntroduced SpeciesInvasion biologyDemographyBMC Evolutionary Biology
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Effect of a 1-year elastic band resistance exercise program on cardiovascular risk profile in postmenopausal women

2018

Objective: The aim of this study was to investigate the effects of a 1-year progressive resistance training program using elastic bands on cardiovascular profile parameters in sedentary postmenopausal (>12 months’ amenorrhea) women. Methods: This longitudinal prospective experimental study included 38 menopausal women who were randomly divided into two groups: an intervention group (IG, n = 18), who completed a progressive resistance training program with elastic bands over the course of 12 months (six exercises for whole body training, three sets × 10 repetitions), and a control group (CG, n = 20) that did not perform any training. Blood analysis and body composition were determined at bas…

Riskmedicine.medical_specialtyWaist030204 cardiovascular system & hematologyBody compositionStatistics NonparametricC-reactive protein03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRisk FactorsInternal medicineEducación Física y DeportivamedicineHumansLongitudinal StudiesProspective StudiesProspective cohort studyTriglyceridesAgedAnalysis of Variancemedicine.diagnostic_testbiologyCholesterolbusiness.industryBody WeightC-reactive proteinObstetrics and GynecologyResistance TrainingCholesterol LDL030229 sport sciencesAnthropometryCircumferenceResistance trainingPostmenopauseC-Reactive ProteinCholesterolchemistryCardiovascular DiseasesBody Compositionbiology.proteinFemaleAmenorrheaWaist Circumferencemedicine.symptomLipid profilebusinessFollow-Up StudiesMenopause
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Appendicular Muscle Mass, Thigh Intermuscular Fat Infiltration, and Risk of Fall in Postmenopausal Osteoporotic Elder Women

2020

<b><i>Background:</i></b> The association between the quantity and composition of skeletal muscle and the decline in physical function in elderly is poorly understood. Therefore, the primary aim of this cross-over study was to investigate the association between thigh intermuscular adipose tissue (IMAT) infiltration, appendicular muscle mass, and risk of fall in postmenopausal osteoporotic elder women. Second, we examined the differences in muscle mass, IMAT, and risk of fall in the same sample of older subjects after being classified as sarcopenic or nonsarcopenic on the basis of the dual-energy X-ray absorptiometry (DXA)-based Appendicular Skeletal Muscle Mass Inde…

SarcopeniaAgingmedicine.medical_specialtyUrologyAdipose tissueRisk of fallThighMuscle massMagnetic resonance imagingAbsorptiometry PhotonmedicineHumansMuscle SkeletalDual-energy X-ray absorptiometryAgedCross-Over Studiesmedicine.diagnostic_testDual-energy X-ray absorptiometrybusiness.industryRisk of fallSkeletal musclemedicine.diseaseIntermuscular fatPostmenopauseCross-Sectional Studiesmedicine.anatomical_structureThighSarcopeniaBody CompositionMuscleAccidental FallsFemaleGeriatrics and GerontologybusinessGerontology
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[Protein intake in community-dwelling postmenopausal women and its relationship with sarcopenia].

2021

Objectives: the general aging of the population is related to the increase in the prevalence of sarcopenic disease; especially among older women, this pathology is closely related to nutrition and specifically to protein consumption in older adults. The aim of our study was to evaluate the possible relationship between a low protein intake and a higher prevalence of sarcopenic disease, a worse dietary pattern, and lower physical performance in postmenopausal women living in the community. Material and methods: the study was carried out in a total of 164 independent women over 65 years of age, recruited from a municipal social center in Valencia (Benimaclet). The presence of sarcopenic patho…

SarcopeniaLow proteinPopulationMedicine (miscellaneous)DiseaseEnvironmental healthPrevalenceMedicineHumansSarcopenic obesityeducationAgedAged 80 and overeducation.field_of_studyNutrition and DieteticsPostmenopausal womenbusiness.industryMiddle AgedProtein intakeMicronutrientmedicine.diseasePostmenopauseSarcopeniaFemaleDietary ProteinsIndependent LivingbusinessEnergy IntakeNutricion hospitalaria
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Long-term competitive dynamics of two cryptic rotifer species: diapause and fluctuating conditions.

2015

Life-history traits may have an important role in promoting species coexistence. However, the complexity of certain life cycles makes it difficult to draw conclusions about the conditions for coexistence or exclusion based on the study of short-term competitive dynamics. Brachionus plicatilis and B. manjavacasare two cryptic rotifer species co-occurring in many lakes on the Iberian Peninsula. They have a complex life cycle in which cyclical parthenogenesis occurs with diapausing stages being the result of sexual reproduction. B. plicatilis and B. manjavacasare identical in morphology and size, their biotic niches are broadly overlapping, and they have similar competitive abilities. However,…

Sciencemedia_common.quotation_subjectRotiferaRotiferDiapauseCompetition (biology)AnimalsEcosystemmedia_commonCoexistence theoryEcological nicheLife Cycle StagesMultidisciplinarybiologyEcologyReproductionQRMetamorphosis BiologicalBrachionusbiology.organism_classificationSexual reproductionSalinityLakesPhenotypeMedicineResearch ArticlePloS one
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