Search results for "penetration"
showing 10 items of 168 documents
Mucoadhesive Polymeric Films to Enhance Barbaloin Penetration Into Buccal Mucosa: a Novel Approach to Chemoprevention.
2018
Nowadays, chemoprevention by administering natural supplements is considered an attractive strategy to reverse, suppress, or prevent the evolution of premalignant oral lesions. In particular, Barbaloin exhibits anti-proliferative, anti-inflammatory, and anti-cancer properties, and it results useful in multi-therapy with classic chemotherapeutics. Therefore, in this work, mucoadhesive buccal films, as locoregional drug delivery system able to provide a targeted and efficient therapeutic delivery of Barbaloin, are proposed. Thus, Aloin extract-loaded Eudragit (R) RL100 or Eudragit (R) RS100-based buccal films were designed in order to obtain an easily self-administrable formulation capable of…
Multi-Frequency Estimation of Canopy Penetration Depths from SMAP/AMSR2 Radiometer and IceSAT Lidar Data
2018
In this study, the $\tau-\omega$ model framework is used to derive extinction coefficient and canopy penetration depths from multi-frequency SMAP and AMSR2 retrievals of vegetation optical depth together with ICESat LiDAR vegetation heights. The vegetation extinction coefficient serves as an indicator of how strong absorption and scattering processes within the canopy attenuate microwaves at $\mathrm{L}$ and C-band. Through inversion of the extinction coefficient, the penetration depth into the canopy can be obtained, which is analyzed on local (Sahel, Illinois) and continental scale (Africa, parts of North America) as well as for a one year time series (04/2015-04/2016). First analyses of …
Estimation of vegetation loss coefficients and canopy penetration depths from SMAP radiometer and IceSAT lidar data
2017
In this study the framework of the τ — ω model is used to derive vegetation loss coefficients and canopy penetration depths from SMAP multi-temporal retrievals of vegetation optical depth, single scattering albedo and ICESat lidar vegetation heights. The vegetation loss coefficients serve as a global indicator of how strong absorption and scattering processes attenuate L-band microwave radiation. By inverting the vegetation loss coefficients, penetration depths into the canopy can be obtained, which are displayed for the global forest reservoirs. A simple penetration index is formed combining vegetation heights and penetration depth estimates. The distribution and level of this index reveal…
Preventing early age chloride migration into low-carbon concrete
2019
The use of substituting cementitious materials (SCMs) to produce low-carbon concrete is escalating. This contributes to reducing the anthropogenic emission of CO2, and to reduce harmful temperature gradients during cement hydration in massive structures. Mature low-carbon concretes are known to perform well on both strength and durability. However, the maturity process is slow compared to that of standard concrete. Structures made from low-carbon concrete are subject to penetration of agents like chloride at early age, accelerating degrading processes. Chloride penetration is a major problem especially to infrastructure, due to seawater proximity and the use of de-icing agents. Solutions fo…
Root canal adaptation and intra-tubular penetration of three fiber-post cementation systems
2018
Background To measure the penetration of three bonding systems for the luting of fiber glass posts in endodontically treated teeth, using confocal laser scanning microscopy (CLSM). Material and Methods A total of 30 maxillary incisors were shaped with the Mtwo system and filled with gutta-percha and Top Seal cement. The sample was divided into three groups (ni=10) according to the bonding system used to cement the posts: Group 1 (Prime&Bond NT and Rebilda DC with a total-etch technique); Group 2 (Futurabond DC and Rebilda DC with a dentin self-etch technique); and Group 3 (BisCem self-adhesive cement). Rhodamine B was added to the bonding systems to allow visualization by CLSM. Three 1-mm t…
Nanocarriers for antioxidant resveratrol: formulation approach, vesicle self-assembly and stability evaluation.
2013
In this work we studied various nanoformulations of resveratrol in phospholipid vesicles. Conventional phophatidylcholine liposomes were prepared and characterized in parallel with PEVs (Penetration Enhancer-containing Vesicles) obtained by adding one of eight selected amphiphilic penetration enhancers (PEs; 0.2% w/v; HLB range 1-16) to the composition. All vesicles were around 100 nm, negatively charged (∼-30 mV) and able to incorporate resveratrol in good yields (>74%). The structure and the lamellar self-organization of the vesicles were investigated by Transmission Electron Microscopy (TEM) and Small and Wide Angle X-ray Scattering (SWAXS). These analyses showed that the lamellarity of …
Penetration enhancer containing vesicles as carriers for dermal delivery of tretinoin.
2011
The ability of a recently developed novel class of liposomes to promote dermal delivery of tretinoin (TRA) was evaluated. New penetration enhancer-containing vesicles (PEVs) were prepared adding to conventional phosphatidylcholine vesicles (control liposomes) different hydrophilic penetration enhancers: Oramix® NS10 (OrNS10), Labrasol® (Lab), Transcutol® P (Trc), and propylene glycol (PG). Vesicles were characterized by morphology, size distribution, zeta potential, incorporation efficiency, stability, rheological behaviour, and deformability. Small, negatively charged, non-deformable, multilamellar vesicles were obtained. Rheological studies showed that PEVs had fluidity higher than conven…
Low temperature plasma treatment of monomolecular Langmuir-Blodgett films
1993
Abstract The structure of the surface layer of materials is usually quite different from the bulk. Detailed information about the surface structure is often not available. This, together with the complex nature of low temperature plasma treatment, hinders the investigations of plasma chemical processes on solid surfaces. Monomolecular Langmuir-Blodgett (LB) structures offer a unique opportunity to prepare model surfaces with known thickness and molecular architecture. From the data obtained, the depth of the Ar plasma influence on solid organic surfaces was estimated to be about 400–1000 A depending on the nature of the surface layer. An oxygen plasma penetrates deeper with a penetration li…
Influence of ground tire rubber on the transient loading response of a peat biofilter
2010
Abstract The effect of using ground tire rubber (GTR) as an adsorptive material in the removal of a 2:1:1 weight mixture of n-butyl acetate, toluene and m-xylene by using a peat biofilter under different intermittent conditions was investigated. The performance of two identical size biofilters, one packed with fibrous peat alone and the other with a 3:1 (vol) fibrous peat and GTR mixture, was examined for a period of four months. Partition coefficients of both materials were measured. Values of 53, 118 and 402 L kg −1 were determined for n-butyl acetate, toluene and m-xylene in peat, respectively; and values of 40, 609 and 3035 L kg −1 were measured for the same compounds in GTR. Intermitte…
Influence of impregnation solution viscosity and osmolarity on solute uptake during vacuum impregnation of apple cubes (var. Granny Smith)
2008
Vacuum-assisted impregnation of pectinmethylesterase (PME) solution has been recognized as an efficient pretreatment to improve the firmness of heat-treated fruit. In order to improve the control of solute infusion into fruit pieces, the effect of the osmolarity and viscosity of vacuum impregnation solution on solute penetration and distribution was studied in 1.5 cm apple cubes, using model PME-based solutions containing sodium chloride and/or sodium alginate. While vacuum impregnation of either a viscous hypotonic or a non-viscous hypertonic solution infused solutes homogeneously into fruit pieces, the penetration of viscous hypertonic solutions was much lower, and PME or chloride infusio…