Search results for "performance"
showing 10 items of 4457 documents
The macroeconomic effects of public investment: Evidence from advanced economies
2015
This paper provides new evidence of the macroeconomic effects of public investment in advanced economies. Using public investment forecast errors to identify the causal effect of government investment in a sample of 17 OECD economies since 1985 and model simulations, the paper finds that increased public investment raises output, both in the short term and in the long term, crowds in private investment, and reduces unemployment. Several factors shape the macroeconomic effects of public investment. When there is economic slack and monetary accommodation, demand effects are stronger, and the public-debt-to-GDP ratio may actually decline. Public investment is also more effective in boosting ou…
High Performance Computing on the COMETA Grid Infrastructure
2008
We present the High Performance Computing (HPC) projects jointly developed at the INAF - Osservatorio Astronomico di Palermo and at the DSFA - Universita` di Palermo which benefits of the Grid infrastructure of COMETA. We have contributed to setup the infrastructure in order to run HPC applications on the Grid. We report on our experience regarding to porting HPC applications to the Grid and to the first HPC simulations performed. The most demanding simulations describe the interaction of a magnetized supernova shock wave with an interstellar gas cloud. We discuss the resources required for the simulations, the performance and the scalability of our code on the Grid, and present first resul…
Networking strategy for competitive advantage
2011
This paper explores the potential of networking strategy as a source of competitive advantage by integrating market- based and resource-based logics. It contributes to operations management literature by considering not just supply chain structures but also others kinds of network that can emerge from horizontal agreements (i.e. alliances, partnerships, joint ventures, etc.). The paper reviews the literature and develops propositions regarding how make/buy/make together decisions, governance mechanisms and network-base structures allow firms both to pursue operations performance objectives and obtain/create valuable resources. A case study supports the propositions and shows a practical app…
A field test of behavioural flexibility in Zenaida doves (Zenaida aurita).
2010
7 pages; International audience; Animals' ability to adjust their behaviour when environmental conditions change can increase their likelihood of survival. Although such behavioural flexibility is regularly observed in the field, it has proven difficult to systematically quantify and predict inter-individual differences in free-living animals. We presented 24 Zenaida doves (Zenaida aurita) on 12 territories with two learning tests in their natural habitat in Barbados. The dove pairs showed high site fidelity and territoriality, allowing us to test individuals repeatedly while accounting for the effects of territorial chases and pair bonds on our learning measures. We used a foraging apparat…
Fungal-Mediated Multitrophic Interactions : Do Grass Endophytes in Diet Protect Voles from Predators?
2009
Plant-associated micro-organisms such as mycotoxin-producing endophytes commonly have direct negative effects on herbivores. These effects may be carried over to natural enemies of the herbivores, but this has been rarely explored. We examined how feeding on Neotyphodium endophyte infected (E+) and endophyte free (E−) meadow ryegrass (Scherodonus pratensis) affects body mass, population size and mobility of sibling voles (Microtus levis), and whether the diet mediates the vulnerability of voles to least weasel (Mustela nivalis nivalis) predation. Because least weasels are known to be olfactory hunters, we also examined whether they are able to distinguish olfactory cues of voles fed on E+ a…
Pre-exercise skin temperature evolution is not related with 100 m front crawl performance
2020
During the transition between warm-up and competition there is a change in core, muscle and (eventually) skin temperature that may affect swimming performance. We have aimed to assess skin temperature evolution during transition phases of different durations before a typical front crawl effort and to investigate its relationship with performance. Following a standardized warm-up, nine adolescent male swimmers performed three maximal randomized 100 m maximum front crawl trials after 10, 20 and 45 min transition phases. Skin temperature, performance (time, stroke frequency, length and index, and propelling efficiency), heart rate, lactate and perceived effort were assessed. Data showed a skin…
Overrating Classifier Performance in ROC Analysis in the Absence of a Test Set: Evidence from Simulation and Italian CARATkids Validation
2019
Background The use of receiver operating characteristic curves, or “ROC analysis,” has become quite common in biomedical research to support decisions. However, sensitivity, specificity, and misclassification rates are still often estimated using the training sample, overlooking the risk of overrating the test performance. Methods A simulation study was performed to highlight the inferential implications of splitting (or not) the dataset into training and test set. The normality assumption was made for the classifier given the disease status, and the Youden's criterion considered for the detection of the optimal cutoff. Then, an ROC analysis with sample split was applied to assess the disc…
Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metab…
2021
Gut: first published.
Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex Enhances Recognition Memory in Alzheimer’s Dis…
2019
Background: The lack of effective pharmacological or behavioral interventions for memory impairments associated with Alzheimer’s disease (AD) emphasizes the need for the investigation of approaches based on neuromodulation. Objective: This study examined the effects of inhibitory repetitive transcranial magnetic stimulation (rTMS) of prefrontal cortex on recognition memory in AD patients. Methods: In a first experiment, 24 mild AD patients received sham and real 1Hz rTMS over the left and right dorsolateral prefrontal cortex (DLPFC), in different sessions, between encoding and retrieval phases of a non-verbal recognition memory task. In a second experiment, another group of 14 AD patients u…
Predictive factors of severe early treatment-related toxicity in patients receiving first-line treatment for metastatic colorectal cancer: Pooled ana…
2021
Few studies have explored the association between baseline characteristics and the occurrence of early toxicities in patients treated with first-line chemotherapy for metastatic colorectal cancer (mCRC).Individual patient data of 2190 patients enrolled in 10 prospective FFCD (Fédération Francophone de Cancérologie Digestive) trials were analysed. Severe early toxicity was defined as the occurrence of grade ≥III toxicity within 3 months after initiation of chemotherapy (ET3).Patients received monotherapy based on 5-FU (n = 1068), a cytotoxic doublet (n = 395) or tritherapy with a cytotoxic doublet plus anti-VEGF agent or a cytotoxic triplet (n = 727). The patients received 5-FU (100%), Irino…