Search results for "peripheral"
showing 8 items of 1028 documents
Interleukin 12 enhances deficient HCV-antigen-induced Th1-type immune response of peripheral blood mononuclear cells
1998
The aim of this study was to examine the possible immunomodulating effects of rhIL-12 on the immune response induced by different hepatitis C virus (HCV) antigens. Freshly isolated peripheral blood mononuclear cells (PBMC) of 33 patients with chronic HCV infection were stimulated with optimal concentrations of antigens from the NS3, NS4, NS5, and core region of HCV in the absence or presence of interleukin12 (IL-12). Stimulation by α-CD3 + α-CD28, lipopolysaccharide (LPS), and pokeweed mitogen (PWM) were used as controls. Proliferation and cytokine production were determined by 3H-thymidine uptake and enzyme-linked immunosorbent assay (ELISA) after 72 hr. After stimulation with antigen or a…
High-Frequency and Ultra-High Frequency Ultrasound: Musculoskeletal Imaging up to 70 MHz
2020
AbstractMusculoskeletal (MSK) ultrasound has well-established advantages, able to investigate very small structures with high resolution and a quick and real-time dynamic evaluation with the possibility of contralateral comparison. Thus ultrasound has kept its own almost exclusive fields of application in daily clinical practice, and it is considered the first-level imaging technique to assess tendons, bursae, and capsuloligamentous structures of small peripheral joints as well as peripheral nerves. Up to now, however, clinical MSK ultrasound imaging could not go beyond the first 1 to 2 cm under the skin, using high-frequency probes up to 18 to 20 MHz with spatial resolution just below mill…
Peripherally Induced Regulatory T Cells: Recruited Protectors of the Central Nervous System against Autoimmune Neuroinflammation
2017
Defects in regulatory T cells (Treg cells) aggravate multiple sclerosis (MS) after its onset and the absence of Treg cell functions can also exacerbate the course of disease in an animal model of MS. However, autoimmune neuroinflammation in many MS models can be acutely provoked in healthy animals leading to an activation of encephalitogenic T cells despite the normal induction of immune tolerance in the thymus including thymically-produced (t)Treg cells. In contrast, neuroinflammation can be ameliorated or even completely prevented by the antigen-specific Treg cells formed extrathymically in the peripheral immune system (pTreg cells) during tolerogenic responses to relevant neuronal antige…
New Metropolitan Perspectives Transition with Resilience for Evolutionary Development
2023
This open access book conveys attention to the theme of transition towards resilience and sustainability and its evolutionary perspective that emphasizes the complexity and uncertainty that governments and society are called to address in response to the ongoing challenges. "New Metropolitan Perspective Post COVID Dynamics: Green and Digital Transition, between Metropolitan and Return to Villages’ Perspectives”, 25–27 May 2022, Reggio Calabria, Italy. The papers included in the book are grouped around the following main topics: the envisaged transition towards resilience and sustainability; the relevance of the planning dimension for defining sustainable development pathways and managing co…
Perifērās neiropātijas izmeklēšana hemodialīzes pacientiem
2018
Pamatinformācija: Hroniska nieru slimība (HNS) ir globāla veselības problēma, kuras vidējā izplatība Eiropā ir 18.4 %. Perifērā neiropātija (PN) ir visizplatītākā neiroloģiskā komplikācija (~ 60 līdz 100 %) šiem pacientiem. PN diagnoze ietver padziļinātu klīnisko izmeklēšanu, tai skaitā pacienta slimības vēstures analīzi, neiroloģisko izmeklēšanu, laboratorisko testēšanu un elektrofizioloģiskās izmeklēšanas metodes. Skrīninga metodes var palīdzēt agrīni noteikt PN HNS pacientiem un laicīgi sākt terapiju, mainot slimības attīstības gaitu. Mērķis: Noteikt perifēro neiropātiju HNS pacientiem ar Mičiganas neiropātijas skrīninga metodes (MNSI) palīdzību, kas apstiprināta un pielietota cukura dia…
Computer Structure Laboratory
2019
La asignatura "Estructura de Computadores" es una asignatura obligatoria de segundo curso del Grado en Ingeniería Multimedia y del Grado en Ingeniería Informática. Tiene asignada una dedicación de 6 ECTS, siendo de carácter obligatorio en los dos grados. El material desarrollado son un total de 8 sesiones de laboratorio de 2 horas y media cada una, donde se estudia: jerarquía de memoria, centrándose en la memoria cache (3 sesiones), entrada y salida (2 sesiones) y periféricos (3 sesiones). En las 5 primeras prácticas se utiliza un software (MipsIt) que simula una máquina MIPS. En las 3 últimas sesiones se utiliza una máquina virtual con Linux. Las prácticas parten de ejemplos ya preparados …
Do Physiological Responses and Personality Traits Relate to Auditory Perceptual Learning in Musicians and Non-Musicians?
2009
Peripheral nervous system can influence learning and memory functions by increasing the activity level (‘arousal’) of the system with increasing task difficulty. Several studies show that musicians discriminate auditory stimuli more effectively both neurally and behaviourally. Yet, the effects of individual peripheral nervous responses or personality during auditory learning have not been studied in musicians. In this paper, we show preliminary evidence on physiological differences between musicians and non-musicians during auditory perceptual learning. Results suggest that musicians have higher change in skin temperature and heart rate between resting state and active auditory discriminati…
Arterial Aneurysms
2021
Aquest document ha estat revisat pel Servei de Política Lingüística de la Universitat de València en el context de la seva presentació als Premis Fernando Sapiña a material docent en valencià i anglès Classe per a estudiants de tercer curs del grau de Medicina. Assignatura Gr AR (34479): Pathology of the Cardiocirculatory system. Tema 23:Arterial Aneurysms Class for third year students of the bachelor's degree in Medicine. Subject Gr AR (34479): Pathology of the cardiocirculatory system. Unit 23: Arterial Aneurysms