Search results for "permeability"

showing 10 items of 596 documents

Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress

2014

Background and Purpose The hippocampal cell line HT22 is an excellent model for studying the consequences of endogenous oxidative stress. Extracellular glutamate depletes cellular glutathione by blocking the glutamate/cystine antiporter system xc−. Glutathione depletion induces a well-defined programme of cell death characterized by an increase in reactive oxygen species and mitochondrial dysfunction. Experimental Approach We compared the mitochondrial shape, the abundance of mitochondrial complexes and the mitochondrial respiration of HT22 cells, selected based on their resistance to glutamate, with those of the glutamate-sensitive parental cell line. Key Results Glutamate-resistant mitoch…

PharmacologyOligomycinATP synthaseCellular respirationOxidative phosphorylationMitochondrionBiologymedicine.disease_causechemistry.chemical_compoundMitochondrial permeability transition poreBiochemistrychemistrymedicinebiology.proteinATP–ADP translocaseOxidative stressBritish Journal of Pharmacology
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Computer simulation of oxygen tension histograms--a possibility for interpretation of microelectrode measurements.

1972

Mit Sauerstoff-Mikroelektroden werden die lokalen Werte des Sauerstoffpartialdruckes im Mikrobereich der Organe gemessen und graphisch als Haufigkeitsverteilungen (Histogramme) dargestellt. Theoretisch wird der Einfluss der Kapillaranordnung (Gleich-, Gegenstromsystem und Kapillarnetzwerk) auf die Haufigkeitsverteilung der P02 Werte untersucht. Die fur zweidimensionale Modelle durchgefuhrte Analyse zeigt, dass Unterschiede in der Durchblutung, wie sie in den einzelnen Zweigen der Kapillarnetzwerke auftreten, einen starken Einfluss auf die Histogramme haben.

PharmacologyPhysicsBrain ChemistryComputersMicrocirculationAnalytical chemistryCell BiologyModels TheoreticalOxygen tensionInterpretation (model theory)Capillary PermeabilityOxygenCellular and Molecular NeuroscienceMicroelectrodeOxygen ConsumptionCerebrovascular CirculationMolecular MedicineMolecular BiologyMicroelectrodesExperientia
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Digital rock physics, chemistry, and biology: challenges and prospects of pore-scale modelling approach

2021

Abstract Conventional and unconventional hydrocarbon rocks have complicated pore structures with heterogeneities distributed over various length scales (from nanometre to centimetre or even larger scales). Effective characterization of the properties of such rocks based on their digital twins is a challenging task. Digital rock physics (DRP) can be used to quantify the structural and morphological parameters of rocks directly and predict flow transport properties at the pore scale. Digital rock chemistry (DRC) or biology (DRB) applies when the changes in pore structures are due to interaction with solutes or microbial activities. Fluid–rock interactions or microbial activities complicate fl…

PhysicsChemistryFlow (psychology)Direct numerical simulation010501 environmental sciencesBiology010502 geochemistry & geophysics01 natural sciencesPollutionCharacterization (materials science)Permeability (earth sciences)Geochemistry and PetrologyVoid (composites)Fluid dynamicsEnvironmental ChemistryPorosityBiological system0105 earth and related environmental sciencesNetwork modelApplied Geochemistry
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Influence of electromagnetic boundary conditions onto the onset of dynamo action in laboratory experiments

2009

We study the onset of dynamo action of the Riga and Karlsruhe experiments with the addition of an external wall, the electro-magnetic properties of which being different from those of the fluid in motion. We consider a wall of different thickness, conductivity and permeability. We also consider the case of a ferro-fluid in motion.

PhysicsFerrofluid[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Mechanics of the fluids [physics.class-ph][SDU.STU.GP]Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph]Fluid Dynamics (physics.flu-dyn)FOS: Physical sciences[PHYS.PHYS.PHYS-GEO-PH]Physics [physics]/Physics [physics]/Geophysics [physics.geo-ph]Physics - Fluid DynamicsConductivity01 natural sciences010305 fluids & plasmas[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph]Physics::GeophysicsGeophysics (physics.geo-ph)Physics - GeophysicsPhysics::Fluid DynamicsClassical mechanicsPermeability (electromagnetism)0103 physical sciencesBoundary value problem[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph]010306 general physicsDynamo
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A semi-3D method of calculating the magnetic field in a conventional sector-focused cyclotron

1991

Abstract A semi-3D method to calculate the median plane magnetic field in a conventional sector-focused cyclotron was developed in order to avoid the need of model magnet studies in the design of the Jyvaskyla K130 cyclotron. The method gives reasonably good results especially at high fields. At low fields where the relative permeability of iron is high the field can be calculated assuming constant magnetic scalar potential on the iron surfaces and solving a three-dimensional Laplace equation. The field calculation methods will be described and the comparison of calculated and measured fields will be given.

PhysicsLaplace's equationNuclear and High Energy PhysicsCondensed matter physicsCyclotronScalar potentialMagnetic fieldComputational physicslaw.inventionMedian planePermeability (electromagnetism)lawMagnetRelative permeabilityInstrumentationNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
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Digital rock physics: Effect of fluid viscosity on effective elastic properties

2011

Abstract This paper is concerned with the effect of pore fluid viscosity on effective elastic properties using digitized rocks. We determine a significant velocity dispersion in wave propagation simulations by the variation of the pore fluid viscosity. Several attenuation regimes are considered which may contribute to this observation. Starting point is a virtual rock physics approach. Numerical simulations of effective transport and effective mechanical properties are applied to statistically representative rock samples. The rock microstructure is imaged by 3D X-ray tomography. Permeability values were estimated through Lattice-Boltzmann flow simulations. The dry rock moduli and the tortuo…

PhysicsPermeability (earth sciences)ViscosityGeophysicsWave propagationAttenuationNewtonian fluidMechanicsWave equationTortuosityPhysics::GeophysicsRock microstructureJournal of Applied Geophysics
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Local-porosity theory for flow in porous media

1992

A recently introduced geometric characterization of porous media based on local-porosity distributions and local-percolation probabilities is used to calculate dc permeabilities for porous media. The disorder in porous media is found to be intimately related to the percolation concept. The geometric characterization is shown to open a possibility for understanding experimentally observed scaling relations between permeability, formation factor, specific internal surface, and porosity. In particular, Kozeny's equation k\ensuremath{\propto}\ensuremath{\varphi}\ifmmode\bar\else\textasciimacron\fi{} $^{\mathit{b}}$ between effective permeability and bulk porosity and the relation k\ensuremath{\…

PhysicsThermodynamicsPorosityRelative permeabilityPorous mediumScalingPhysical Review B
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Modulation instability scenario in negative index materials

2010

We present an investigation of the critical frequency windows permitting modulation instability in negative index materials. The principal motivation for our analysis stems from the impact of the inevitable presence of the effective dispersive magnetic permeability in addition to the effective dielectric permittivity determining the propagation model for ultrashort pulses in negative index materials. We emphasize the influence of nonlinear dispersion terms, arising out of the combinatorial effect of the dispersive permeability with the nonlinear polarization, over the MI phenomena, the outcome of its development achieved by using linear stability analysis. Gain spectrum investigation has be…

Physicsbusiness.industryNonlinear dispersionDirect numerical simulationDielectric permittivityInstabilityAtomic and Molecular Physics and OpticsComputational physicsNonlinear systemOpticsCritical frequencyPermeability (electromagnetism)Linear stability analysisbusinessJournal of Modern Optics
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Equivalent continuum-based upscaling of flow in discrete fracture networks: The fracture-and-pipe model

2021

Abstract. Predicting effective permeabilities of fractured rock masses is a key component of reservoir modelling. This is often realized with the discrete fracture network (DFN) method, where single-phase incompressible fluid flow is modelled in discrete representations of individual fractures in a network. Depending on the overall number of fractures, this can result in significant computational costs. Equivalent continuum models (ECM) provide an alternative approach by subdividing the fracture network into a grid of continuous medium cells, over which hydraulic properties are averaged for fluid flow simulations. While this has the advantage of lower computational costs and the possibility…

Physics::Fluid DynamicsPermeability (earth sciences)DiscretizationFlow (mathematics)Fracture (geology)Fluid dynamicsMechanicsAnisotropyParametrizationGeologyPhysics::GeophysicsPipe flow
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Permeability and effective porosity of porous media

1997

The concept of permeability of porous media is discussed, and a modification of Kozeny’s permeability equation to include the effect of effective porosity is introduced. An analytical expression for the specific surface area of a system constructed of randomly placed identical obstacles with unrestricted overlap is derived, and a lattice-gas cellular automaton method is then used to simulate the dependence on porosity of permeability, tortuosity, and effective porosity for a flow of Newtonian uncompressible fluid in this two-dimensional porous substance. The simulated permeabilities can well be explained by the concept of effective porosity, and the exact form of the specific surface area. …

Physics::Fluid DynamicsPermeability (earth sciences)Materials scienceNewtonian fluidNuclear magnetic resonance in porous mediaPercolation thresholdMechanicsPhysics::Classical PhysicsPorosityPorous mediumEffective porosityTortuosityPhysics::GeophysicsPhysical Review E
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